| Full name: mitochondrial ribosomal protein L17 | Alias Symbol: RPML26|MRP-L26 | ||
| Type: protein-coding gene | Cytoband: 11p15.5-p15.4 | ||
| Entrez ID: 63875 | HGNC ID: HGNC:14053 | Ensembl Gene: ENSG00000158042 | OMIM ID: 611830 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MRPL17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL17 | 63875 | 222216_s_at | 0.3416 | 0.1038 | |
| GSE20347 | MRPL17 | 63875 | 222216_s_at | 0.2891 | 0.0987 | |
| GSE23400 | MRPL17 | 63875 | 222216_s_at | 0.5750 | 0.0000 | |
| GSE26886 | MRPL17 | 63875 | 222216_s_at | 0.4713 | 0.0116 | |
| GSE29001 | MRPL17 | 63875 | 222216_s_at | 0.3916 | 0.3402 | |
| GSE38129 | MRPL17 | 63875 | 222216_s_at | 0.4460 | 0.0002 | |
| GSE45670 | MRPL17 | 63875 | 222216_s_at | 0.4667 | 0.0008 | |
| GSE53622 | MRPL17 | 63875 | 50431 | 0.6638 | 0.0000 | |
| GSE53624 | MRPL17 | 63875 | 50431 | 0.6444 | 0.0000 | |
| GSE63941 | MRPL17 | 63875 | 222216_s_at | 0.4257 | 0.3554 | |
| GSE77861 | MRPL17 | 63875 | 222216_s_at | 0.2938 | 0.2463 | |
| GSE97050 | MRPL17 | 63875 | A_23_P87257 | 0.6221 | 0.0995 | |
| SRP007169 | MRPL17 | 63875 | RNAseq | 0.4757 | 0.2392 | |
| SRP008496 | MRPL17 | 63875 | RNAseq | 0.6317 | 0.0063 | |
| SRP064894 | MRPL17 | 63875 | RNAseq | 0.6569 | 0.0074 | |
| SRP133303 | MRPL17 | 63875 | RNAseq | 0.4033 | 0.0031 | |
| SRP159526 | MRPL17 | 63875 | RNAseq | 0.0356 | 0.9073 | |
| SRP193095 | MRPL17 | 63875 | RNAseq | -0.0695 | 0.6074 | |
| SRP219564 | MRPL17 | 63875 | RNAseq | 0.4847 | 0.1152 | |
| TCGA | MRPL17 | 63875 | RNAseq | 0.1706 | 0.0045 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPL17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPL17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL17 | 63875 | 1 | 11 | 18 | |
| GSE20123 | MRPL17 | 63875 | 1 | 11 | 18 | |
| GSE43470 | MRPL17 | 63875 | 1 | 8 | 34 | |
| GSE46452 | MRPL17 | 63875 | 7 | 8 | 44 | |
| GSE47630 | MRPL17 | 63875 | 2 | 12 | 26 | |
| GSE54993 | MRPL17 | 63875 | 3 | 1 | 66 | |
| GSE54994 | MRPL17 | 63875 | 2 | 12 | 39 | |
| GSE60625 | MRPL17 | 63875 | 0 | 0 | 11 | |
| GSE74703 | MRPL17 | 63875 | 1 | 6 | 29 | |
| GSE74704 | MRPL17 | 63875 | 0 | 8 | 12 | |
| TCGA | MRPL17 | 63875 | 9 | 38 | 49 |
Total number of gains: 27; Total number of losses: 115; Total Number of normals: 346.
Somatic mutations of MRPL17:
Generating mutation plots.
Highly correlated genes for MRPL17:
Showing top 20/1692 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL17 | MZT1 | 0.774119 | 3 | 0 | 3 |
| MRPL17 | RNF4 | 0.759374 | 3 | 0 | 3 |
| MRPL17 | PRELID1 | 0.746047 | 3 | 0 | 3 |
| MRPL17 | CENPBD1 | 0.745142 | 3 | 0 | 3 |
| MRPL17 | NACC1 | 0.743661 | 3 | 0 | 3 |
| MRPL17 | GPR153 | 0.741968 | 4 | 0 | 4 |
| MRPL17 | PSMG3 | 0.734583 | 7 | 0 | 6 |
| MRPL17 | EBNA1BP2 | 0.733915 | 3 | 0 | 3 |
| MRPL17 | KTI12 | 0.73114 | 3 | 0 | 3 |
| MRPL17 | SCNM1 | 0.72894 | 3 | 0 | 3 |
| MRPL17 | AGTRAP | 0.72156 | 3 | 0 | 3 |
| MRPL17 | TMEM189 | 0.719098 | 3 | 0 | 3 |
| MRPL17 | CD44 | 0.715499 | 3 | 0 | 3 |
| MRPL17 | ZNF707 | 0.710998 | 3 | 0 | 3 |
| MRPL17 | EXOSC4 | 0.710911 | 11 | 0 | 9 |
| MRPL17 | PMS2 | 0.71026 | 3 | 0 | 3 |
| MRPL17 | CCM2 | 0.707298 | 7 | 0 | 7 |
| MRPL17 | DHRS13 | 0.704512 | 3 | 0 | 3 |
| MRPL17 | MRPL14 | 0.701216 | 7 | 0 | 6 |
| MRPL17 | ZNF584 | 0.700865 | 3 | 0 | 3 |
For details and further investigation, click here
