| Full name: POZ/BTB and AT hook containing zinc finger 1 | Alias Symbol: MAZR|dJ400N23|ZBTB19|ZSG|RIAZ|PATZ | ||
| Type: protein-coding gene | Cytoband: 22q12.2 | ||
| Entrez ID: 23598 | HGNC ID: HGNC:13071 | Ensembl Gene: ENSG00000100105 | OMIM ID: 605165 |
| Drug and gene relationship at DGIdb | |||
Expression of PATZ1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PATZ1 | 23598 | 209431_s_at | 0.4578 | 0.2450 | |
| GSE20347 | PATZ1 | 23598 | 209431_s_at | 0.7548 | 0.0000 | |
| GSE23400 | PATZ1 | 23598 | 209494_s_at | 0.1125 | 0.0510 | |
| GSE26886 | PATZ1 | 23598 | 209431_s_at | 1.7635 | 0.0000 | |
| GSE29001 | PATZ1 | 23598 | 209431_s_at | 0.7568 | 0.0215 | |
| GSE38129 | PATZ1 | 23598 | 209431_s_at | 0.7030 | 0.0002 | |
| GSE45670 | PATZ1 | 23598 | 209431_s_at | 0.0188 | 0.9587 | |
| GSE53622 | PATZ1 | 23598 | 131863 | 0.5770 | 0.0000 | |
| GSE53624 | PATZ1 | 23598 | 131863 | 0.4763 | 0.0000 | |
| GSE63941 | PATZ1 | 23598 | 209431_s_at | 0.8054 | 0.0292 | |
| GSE77861 | PATZ1 | 23598 | 211392_s_at | 0.0407 | 0.8462 | |
| GSE97050 | PATZ1 | 23598 | A_24_P211558 | 0.0857 | 0.7659 | |
| SRP007169 | PATZ1 | 23598 | RNAseq | 1.5811 | 0.0067 | |
| SRP008496 | PATZ1 | 23598 | RNAseq | 1.3726 | 0.0005 | |
| SRP064894 | PATZ1 | 23598 | RNAseq | 0.5910 | 0.0092 | |
| SRP133303 | PATZ1 | 23598 | RNAseq | 0.0941 | 0.7004 | |
| SRP159526 | PATZ1 | 23598 | RNAseq | 1.0422 | 0.0098 | |
| SRP193095 | PATZ1 | 23598 | RNAseq | 0.6045 | 0.0003 | |
| SRP219564 | PATZ1 | 23598 | RNAseq | 0.5344 | 0.0910 | |
| TCGA | PATZ1 | 23598 | RNAseq | -0.0291 | 0.6841 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by PATZ1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PATZ1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PATZ1 | 23598 | 4 | 5 | 21 | |
| GSE20123 | PATZ1 | 23598 | 4 | 4 | 22 | |
| GSE43470 | PATZ1 | 23598 | 4 | 5 | 34 | |
| GSE46452 | PATZ1 | 23598 | 31 | 1 | 27 | |
| GSE47630 | PATZ1 | 23598 | 8 | 5 | 27 | |
| GSE54993 | PATZ1 | 23598 | 3 | 6 | 61 | |
| GSE54994 | PATZ1 | 23598 | 12 | 8 | 33 | |
| GSE60625 | PATZ1 | 23598 | 5 | 0 | 6 | |
| GSE74703 | PATZ1 | 23598 | 4 | 5 | 27 | |
| GSE74704 | PATZ1 | 23598 | 1 | 1 | 18 | |
| TCGA | PATZ1 | 23598 | 27 | 15 | 54 |
Total number of gains: 103; Total number of losses: 55; Total Number of normals: 330.
Somatic mutations of PATZ1:
Generating mutation plots.
Highly correlated genes for PATZ1:
Showing top 20/1247 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PATZ1 | SLC39A3 | 0.826473 | 3 | 0 | 3 |
| PATZ1 | SSBP4 | 0.797249 | 4 | 0 | 4 |
| PATZ1 | POLRMT | 0.785932 | 3 | 0 | 3 |
| PATZ1 | CRTC2 | 0.779247 | 3 | 0 | 3 |
| PATZ1 | MRPL55 | 0.773724 | 3 | 0 | 3 |
| PATZ1 | KRTCAP2 | 0.76912 | 3 | 0 | 3 |
| PATZ1 | DHRSX | 0.759095 | 3 | 0 | 3 |
| PATZ1 | SFT2D3 | 0.754836 | 3 | 0 | 3 |
| PATZ1 | ZNF827 | 0.749941 | 4 | 0 | 4 |
| PATZ1 | SPSB2 | 0.745301 | 3 | 0 | 3 |
| PATZ1 | C12orf65 | 0.731013 | 3 | 0 | 3 |
| PATZ1 | CUEDC2 | 0.728739 | 5 | 0 | 4 |
| PATZ1 | ST6GALNAC2 | 0.727265 | 3 | 0 | 3 |
| PATZ1 | TMEM63B | 0.726033 | 3 | 0 | 3 |
| PATZ1 | RAVER1 | 0.725432 | 4 | 0 | 4 |
| PATZ1 | DEDD | 0.724855 | 3 | 0 | 3 |
| PATZ1 | CCNT1 | 0.724631 | 3 | 0 | 3 |
| PATZ1 | HPCAL1 | 0.723209 | 7 | 0 | 7 |
| PATZ1 | FZD6 | 0.723129 | 4 | 0 | 4 |
| PATZ1 | WDR81 | 0.722188 | 3 | 0 | 3 |
For details and further investigation, click here
