| Full name: proline rich 16 | Alias Symbol: DSC54 | ||
| Type: protein-coding gene | Cytoband: 5q23.1 | ||
| Entrez ID: 51334 | HGNC ID: HGNC:29654 | Ensembl Gene: ENSG00000184838 | OMIM ID: 615931 |
| Drug and gene relationship at DGIdb | |||
Expression of PRR16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRR16 | 51334 | 1554867_a_at | 0.0003 | 0.9995 | |
| GSE20347 | PRR16 | 51334 | 220014_at | 0.2505 | 0.0018 | |
| GSE23400 | PRR16 | 51334 | 220014_at | 0.1339 | 0.0004 | |
| GSE26886 | PRR16 | 51334 | 1554867_a_at | 0.0103 | 0.9242 | |
| GSE29001 | PRR16 | 51334 | 220014_at | 0.9926 | 0.0445 | |
| GSE38129 | PRR16 | 51334 | 220014_at | 0.3592 | 0.1654 | |
| GSE45670 | PRR16 | 51334 | 1554867_a_at | -0.1320 | 0.3564 | |
| GSE53622 | PRR16 | 51334 | 13162 | 1.2741 | 0.0000 | |
| GSE53624 | PRR16 | 51334 | 13162 | 1.5091 | 0.0000 | |
| GSE63941 | PRR16 | 51334 | 220014_at | -3.9493 | 0.0061 | |
| GSE77861 | PRR16 | 51334 | 1554867_a_at | -0.0631 | 0.3719 | |
| GSE97050 | PRR16 | 51334 | A_24_P20746 | 0.8976 | 0.1186 | |
| SRP007169 | PRR16 | 51334 | RNAseq | 1.7145 | 0.1258 | |
| SRP133303 | PRR16 | 51334 | RNAseq | 0.8099 | 0.0002 | |
| SRP159526 | PRR16 | 51334 | RNAseq | 1.9323 | 0.0002 | |
| SRP193095 | PRR16 | 51334 | RNAseq | 1.2477 | 0.0000 | |
| SRP219564 | PRR16 | 51334 | RNAseq | 1.5759 | 0.0116 | |
| TCGA | PRR16 | 51334 | RNAseq | 0.2588 | 0.1857 |
Upregulated datasets: 5; Downregulated datasets: 1.
Survival by PRR16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRR16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRR16 | 51334 | 1 | 13 | 16 | |
| GSE20123 | PRR16 | 51334 | 1 | 13 | 16 | |
| GSE43470 | PRR16 | 51334 | 3 | 8 | 32 | |
| GSE46452 | PRR16 | 51334 | 0 | 27 | 32 | |
| GSE47630 | PRR16 | 51334 | 0 | 21 | 19 | |
| GSE54993 | PRR16 | 51334 | 9 | 1 | 60 | |
| GSE54994 | PRR16 | 51334 | 2 | 14 | 37 | |
| GSE60625 | PRR16 | 51334 | 0 | 0 | 11 | |
| GSE74703 | PRR16 | 51334 | 2 | 6 | 28 | |
| GSE74704 | PRR16 | 51334 | 1 | 7 | 12 | |
| TCGA | PRR16 | 51334 | 2 | 42 | 52 |
Total number of gains: 21; Total number of losses: 152; Total Number of normals: 315.
Somatic mutations of PRR16:
Generating mutation plots.
Highly correlated genes for PRR16:
Showing top 20/724 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRR16 | LRRC8C | 0.784386 | 3 | 0 | 3 |
| PRR16 | FGF7 | 0.772073 | 3 | 0 | 3 |
| PRR16 | RAB34 | 0.755985 | 3 | 0 | 3 |
| PRR16 | FCGR3A | 0.75587 | 3 | 0 | 3 |
| PRR16 | CABLES1 | 0.746334 | 3 | 0 | 3 |
| PRR16 | PPP3CC | 0.732196 | 3 | 0 | 3 |
| PRR16 | ANKRD44 | 0.724036 | 3 | 0 | 3 |
| PRR16 | CERKL | 0.713637 | 3 | 0 | 3 |
| PRR16 | GXYLT2 | 0.712362 | 3 | 0 | 3 |
| PRR16 | KPNA6 | 0.709427 | 3 | 0 | 3 |
| PRR16 | PYCR2 | 0.707846 | 3 | 0 | 3 |
| PRR16 | BOLA3 | 0.694342 | 3 | 0 | 3 |
| PRR16 | UBB | 0.693976 | 3 | 0 | 3 |
| PRR16 | CDK14 | 0.69372 | 8 | 0 | 7 |
| PRR16 | PPP2CB | 0.693249 | 3 | 0 | 3 |
| PRR16 | PDIA5 | 0.690617 | 3 | 0 | 3 |
| PRR16 | DNTTIP1 | 0.688879 | 3 | 0 | 3 |
| PRR16 | TMEM173 | 0.688301 | 4 | 0 | 4 |
| PRR16 | KTI12 | 0.688154 | 3 | 0 | 3 |
| PRR16 | BICC1 | 0.687795 | 10 | 0 | 9 |
For details and further investigation, click here
