| Full name: pellino E3 ubiquitin protein ligase family member 3 | Alias Symbol: MGC35521 | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 246330 | HGNC ID: HGNC:30010 | Ensembl Gene: ENSG00000174516 | OMIM ID: 609827 |
| Drug and gene relationship at DGIdb | |||
Expression of PELI3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PELI3 | 246330 | 235431_s_at | 0.2938 | 0.6174 | |
| GSE26886 | PELI3 | 246330 | 235431_s_at | 0.7754 | 0.0002 | |
| GSE45670 | PELI3 | 246330 | 235431_s_at | -0.0605 | 0.6011 | |
| GSE53622 | PELI3 | 246330 | 4033 | 0.0896 | 0.3132 | |
| GSE53624 | PELI3 | 246330 | 4033 | 0.3739 | 0.0000 | |
| GSE63941 | PELI3 | 246330 | 235431_s_at | -0.2339 | 0.5284 | |
| GSE77861 | PELI3 | 246330 | 235431_s_at | 0.1620 | 0.3131 | |
| GSE97050 | PELI3 | 246330 | A_23_P104692 | -0.3386 | 0.2909 | |
| SRP007169 | PELI3 | 246330 | RNAseq | -0.3511 | 0.4629 | |
| SRP008496 | PELI3 | 246330 | RNAseq | 0.1114 | 0.7564 | |
| SRP064894 | PELI3 | 246330 | RNAseq | 0.0423 | 0.8836 | |
| SRP133303 | PELI3 | 246330 | RNAseq | 0.1539 | 0.5086 | |
| SRP159526 | PELI3 | 246330 | RNAseq | 0.6408 | 0.0019 | |
| SRP193095 | PELI3 | 246330 | RNAseq | 0.4621 | 0.0002 | |
| SRP219564 | PELI3 | 246330 | RNAseq | -0.3057 | 0.5201 | |
| TCGA | PELI3 | 246330 | RNAseq | 0.0148 | 0.8366 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PELI3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PELI3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PELI3 | 246330 | 9 | 4 | 17 | |
| GSE20123 | PELI3 | 246330 | 9 | 4 | 17 | |
| GSE43470 | PELI3 | 246330 | 6 | 1 | 36 | |
| GSE46452 | PELI3 | 246330 | 12 | 3 | 44 | |
| GSE47630 | PELI3 | 246330 | 9 | 4 | 27 | |
| GSE54993 | PELI3 | 246330 | 3 | 0 | 67 | |
| GSE54994 | PELI3 | 246330 | 9 | 5 | 39 | |
| GSE60625 | PELI3 | 246330 | 0 | 3 | 8 | |
| GSE74703 | PELI3 | 246330 | 4 | 0 | 32 | |
| GSE74704 | PELI3 | 246330 | 7 | 2 | 11 | |
| TCGA | PELI3 | 246330 | 26 | 6 | 64 |
Total number of gains: 94; Total number of losses: 32; Total Number of normals: 362.
Somatic mutations of PELI3:
Generating mutation plots.
Highly correlated genes for PELI3:
Showing top 20/176 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PELI3 | ECSIT | 0.762995 | 3 | 0 | 3 |
| PELI3 | RPP25 | 0.709936 | 3 | 0 | 3 |
| PELI3 | SMPX | 0.707362 | 3 | 0 | 3 |
| PELI3 | FOXJ1 | 0.690413 | 3 | 0 | 3 |
| PELI3 | BBX | 0.687913 | 3 | 0 | 3 |
| PELI3 | NPY | 0.687736 | 3 | 0 | 3 |
| PELI3 | RAD23A | 0.68237 | 3 | 0 | 3 |
| PELI3 | CUEDC2 | 0.676107 | 4 | 0 | 4 |
| PELI3 | MRPS26 | 0.674807 | 3 | 0 | 3 |
| PELI3 | HSD11B1L | 0.673981 | 3 | 0 | 3 |
| PELI3 | GPX4 | 0.67227 | 3 | 0 | 3 |
| PELI3 | DPM3 | 0.660913 | 3 | 0 | 3 |
| PELI3 | YBX1 | 0.660493 | 3 | 0 | 3 |
| PELI3 | UST | 0.660087 | 3 | 0 | 3 |
| PELI3 | CEBPD | 0.650384 | 3 | 0 | 3 |
| PELI3 | TMEM150A | 0.648731 | 3 | 0 | 3 |
| PELI3 | ZNF428 | 0.64844 | 5 | 0 | 4 |
| PELI3 | ZNF358 | 0.647861 | 3 | 0 | 3 |
| PELI3 | TRPM2 | 0.644366 | 3 | 0 | 3 |
| PELI3 | MRPL24 | 0.641885 | 3 | 0 | 3 |
For details and further investigation, click here
