| Full name: cylicin 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q31.1 | ||
| Entrez ID: 1539 | HGNC ID: HGNC:2583 | Ensembl Gene: ENSG00000155833 | OMIM ID: 604035 |
| Drug and gene relationship at DGIdb | |||
Expression of CYLC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYLC2 | 1539 | 207780_at | -0.0149 | 0.9541 | |
| GSE20347 | CYLC2 | 1539 | 207780_at | 0.0364 | 0.5738 | |
| GSE23400 | CYLC2 | 1539 | 207780_at | -0.0371 | 0.1039 | |
| GSE26886 | CYLC2 | 1539 | 207780_at | -0.0474 | 0.6275 | |
| GSE29001 | CYLC2 | 1539 | 207780_at | 0.0099 | 0.9312 | |
| GSE38129 | CYLC2 | 1539 | 207780_at | 0.0131 | 0.8412 | |
| GSE45670 | CYLC2 | 1539 | 207780_at | -0.0128 | 0.8780 | |
| GSE53622 | CYLC2 | 1539 | 67831 | -0.0872 | 0.6047 | |
| GSE53624 | CYLC2 | 1539 | 67831 | 0.3036 | 0.0038 | |
| GSE63941 | CYLC2 | 1539 | 207780_at | -0.1396 | 0.2118 | |
| GSE77861 | CYLC2 | 1539 | 207780_at | 0.0100 | 0.9283 | |
| TCGA | CYLC2 | 1539 | RNAseq | 1.1557 | 0.6784 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CYLC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYLC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYLC2 | 1539 | 4 | 10 | 16 | |
| GSE20123 | CYLC2 | 1539 | 5 | 9 | 16 | |
| GSE43470 | CYLC2 | 1539 | 6 | 3 | 34 | |
| GSE46452 | CYLC2 | 1539 | 6 | 13 | 40 | |
| GSE47630 | CYLC2 | 1539 | 1 | 17 | 22 | |
| GSE54993 | CYLC2 | 1539 | 3 | 3 | 64 | |
| GSE54994 | CYLC2 | 1539 | 9 | 11 | 33 | |
| GSE60625 | CYLC2 | 1539 | 0 | 0 | 11 | |
| GSE74703 | CYLC2 | 1539 | 5 | 3 | 28 | |
| GSE74704 | CYLC2 | 1539 | 2 | 6 | 12 | |
| TCGA | CYLC2 | 1539 | 27 | 21 | 48 |
Total number of gains: 68; Total number of losses: 96; Total Number of normals: 324.
Somatic mutations of CYLC2:
Generating mutation plots.
Highly correlated genes for CYLC2:
Showing top 20/252 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYLC2 | KIF5A | 0.669202 | 4 | 0 | 4 |
| CYLC2 | UBE2D4 | 0.664193 | 3 | 0 | 3 |
| CYLC2 | LINC00216 | 0.661702 | 4 | 0 | 4 |
| CYLC2 | NEUROD2 | 0.656858 | 4 | 0 | 4 |
| CYLC2 | PPM1E | 0.653942 | 3 | 0 | 3 |
| CYLC2 | FOLH1 | 0.653405 | 5 | 0 | 5 |
| CYLC2 | SLC6A12 | 0.649802 | 4 | 0 | 4 |
| CYLC2 | ATG10 | 0.645496 | 4 | 0 | 4 |
| CYLC2 | SCN11A | 0.643462 | 4 | 0 | 4 |
| CYLC2 | NCR2 | 0.641925 | 4 | 0 | 4 |
| CYLC2 | CCR9 | 0.638956 | 4 | 0 | 4 |
| CYLC2 | CCDC30 | 0.633414 | 4 | 0 | 3 |
| CYLC2 | DNAJA4 | 0.63248 | 4 | 0 | 4 |
| CYLC2 | GUCA2B | 0.630372 | 4 | 0 | 3 |
| CYLC2 | IFT122 | 0.629311 | 3 | 0 | 3 |
| CYLC2 | SNTG1 | 0.623103 | 4 | 0 | 4 |
| CYLC2 | WRNIP1 | 0.62288 | 4 | 0 | 4 |
| CYLC2 | GRM3 | 0.622829 | 3 | 0 | 3 |
| CYLC2 | KHDRBS2 | 0.621741 | 4 | 0 | 4 |
| CYLC2 | MCF2 | 0.619683 | 3 | 0 | 3 |
For details and further investigation, click here
