| Full name: ubiquitin conjugating enzyme E2 D4 (putative) | Alias Symbol: HBUCE1 | ||
| Type: protein-coding gene | Cytoband: 7p13 | ||
| Entrez ID: 51619 | HGNC ID: HGNC:21647 | Ensembl Gene: ENSG00000078967 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of UBE2D4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2D4 | 51619 | 51774_s_at | -0.0772 | 0.8353 | |
| GSE20347 | UBE2D4 | 51619 | 51774_s_at | 0.2383 | 0.0341 | |
| GSE23400 | UBE2D4 | 51619 | 58900_at | -0.1057 | 0.0014 | |
| GSE26886 | UBE2D4 | 51619 | 51774_s_at | 0.5552 | 0.0032 | |
| GSE29001 | UBE2D4 | 51619 | 58900_at | -0.1539 | 0.3904 | |
| GSE38129 | UBE2D4 | 51619 | 51774_s_at | -0.0330 | 0.7943 | |
| GSE45670 | UBE2D4 | 51619 | 58900_at | -0.0663 | 0.5477 | |
| GSE53622 | UBE2D4 | 51619 | 59608 | -0.1946 | 0.0205 | |
| GSE53624 | UBE2D4 | 51619 | 59608 | -0.0648 | 0.3374 | |
| GSE63941 | UBE2D4 | 51619 | 58900_at | -0.0189 | 0.9527 | |
| GSE77861 | UBE2D4 | 51619 | 58900_at | -0.0950 | 0.3750 | |
| GSE97050 | UBE2D4 | 51619 | A_23_P374767 | -0.1745 | 0.6043 | |
| SRP007169 | UBE2D4 | 51619 | RNAseq | 0.0749 | 0.8771 | |
| SRP008496 | UBE2D4 | 51619 | RNAseq | 0.6783 | 0.0473 | |
| SRP064894 | UBE2D4 | 51619 | RNAseq | 0.0260 | 0.9144 | |
| SRP133303 | UBE2D4 | 51619 | RNAseq | -0.3771 | 0.0001 | |
| SRP159526 | UBE2D4 | 51619 | RNAseq | -0.0624 | 0.7631 | |
| SRP193095 | UBE2D4 | 51619 | RNAseq | -0.1326 | 0.3786 | |
| SRP219564 | UBE2D4 | 51619 | RNAseq | -0.5875 | 0.1867 | |
| TCGA | UBE2D4 | 51619 | RNAseq | -0.1840 | 0.0136 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by UBE2D4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2D4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2D4 | 51619 | 14 | 0 | 16 | |
| GSE20123 | UBE2D4 | 51619 | 13 | 0 | 17 | |
| GSE43470 | UBE2D4 | 51619 | 4 | 0 | 39 | |
| GSE46452 | UBE2D4 | 51619 | 11 | 1 | 47 | |
| GSE47630 | UBE2D4 | 51619 | 8 | 1 | 31 | |
| GSE54993 | UBE2D4 | 51619 | 0 | 8 | 62 | |
| GSE54994 | UBE2D4 | 51619 | 18 | 4 | 31 | |
| GSE60625 | UBE2D4 | 51619 | 0 | 0 | 11 | |
| GSE74703 | UBE2D4 | 51619 | 4 | 0 | 32 | |
| GSE74704 | UBE2D4 | 51619 | 7 | 0 | 13 | |
| TCGA | UBE2D4 | 51619 | 50 | 7 | 39 |
Total number of gains: 129; Total number of losses: 21; Total Number of normals: 338.
Somatic mutations of UBE2D4:
Generating mutation plots.
Highly correlated genes for UBE2D4:
Showing top 20/951 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2D4 | EEPD1 | 0.776933 | 3 | 0 | 3 |
| UBE2D4 | CEACAM4 | 0.770682 | 3 | 0 | 3 |
| UBE2D4 | CAV3 | 0.765287 | 3 | 0 | 3 |
| UBE2D4 | SLC39A13 | 0.760534 | 3 | 0 | 3 |
| UBE2D4 | CER1 | 0.753371 | 3 | 0 | 3 |
| UBE2D4 | IFNA17 | 0.742684 | 4 | 0 | 4 |
| UBE2D4 | USP2 | 0.741804 | 4 | 0 | 4 |
| UBE2D4 | LUZP4 | 0.739715 | 4 | 0 | 4 |
| UBE2D4 | NUDT4 | 0.735531 | 3 | 0 | 3 |
| UBE2D4 | CNTF | 0.733299 | 4 | 0 | 4 |
| UBE2D4 | CDH15 | 0.729069 | 3 | 0 | 3 |
| UBE2D4 | C8A | 0.725055 | 3 | 0 | 3 |
| UBE2D4 | ANO5 | 0.723614 | 3 | 0 | 3 |
| UBE2D4 | KIF5A | 0.723298 | 5 | 0 | 4 |
| UBE2D4 | GABRR2 | 0.719809 | 4 | 0 | 4 |
| UBE2D4 | GP1BA | 0.719242 | 3 | 0 | 3 |
| UBE2D4 | LINC00474 | 0.717126 | 3 | 0 | 3 |
| UBE2D4 | IQUB | 0.71628 | 3 | 0 | 3 |
| UBE2D4 | ADAM22 | 0.712148 | 5 | 0 | 4 |
| UBE2D4 | DENND6B | 0.70961 | 3 | 0 | 3 |
For details and further investigation, click here
