| Full name: cytohesin 2 | Alias Symbol: CTS18.1|Sec7p-L|ARNO|Sec7p-like|cytohesin-2 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 9266 | HGNC ID: HGNC:9502 | Ensembl Gene: ENSG00000105443 | OMIM ID: 602488 |
| Drug and gene relationship at DGIdb | |||
CYTH2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04072 | Phospholipase D signaling pathway |
Expression of CYTH2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYTH2 | 9266 | 209158_s_at | -0.1667 | 0.7020 | |
| GSE20347 | CYTH2 | 9266 | 209158_s_at | -0.6137 | 0.0000 | |
| GSE23400 | CYTH2 | 9266 | 209158_s_at | -0.3619 | 0.0000 | |
| GSE26886 | CYTH2 | 9266 | 209158_s_at | -0.3229 | 0.1303 | |
| GSE29001 | CYTH2 | 9266 | 209158_s_at | -0.4365 | 0.1113 | |
| GSE38129 | CYTH2 | 9266 | 209158_s_at | -0.3515 | 0.0023 | |
| GSE45670 | CYTH2 | 9266 | 209158_s_at | -0.3054 | 0.0090 | |
| GSE63941 | CYTH2 | 9266 | 209158_s_at | -0.2709 | 0.6637 | |
| GSE77861 | CYTH2 | 9266 | 209158_s_at | -0.2455 | 0.1821 | |
| GSE97050 | CYTH2 | 9266 | A_23_P119377 | -0.0822 | 0.6965 | |
| SRP007169 | CYTH2 | 9266 | RNAseq | -0.0110 | 0.9813 | |
| SRP008496 | CYTH2 | 9266 | RNAseq | 0.1676 | 0.5757 | |
| SRP064894 | CYTH2 | 9266 | RNAseq | 0.2200 | 0.3539 | |
| SRP133303 | CYTH2 | 9266 | RNAseq | 0.0181 | 0.9276 | |
| SRP159526 | CYTH2 | 9266 | RNAseq | -0.0297 | 0.8717 | |
| SRP193095 | CYTH2 | 9266 | RNAseq | -0.1599 | 0.3046 | |
| SRP219564 | CYTH2 | 9266 | RNAseq | -0.1537 | 0.5951 | |
| TCGA | CYTH2 | 9266 | RNAseq | -0.0560 | 0.2667 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CYTH2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CYTH2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYTH2 | 9266 | 4 | 4 | 22 | |
| GSE20123 | CYTH2 | 9266 | 4 | 3 | 23 | |
| GSE43470 | CYTH2 | 9266 | 4 | 11 | 28 | |
| GSE46452 | CYTH2 | 9266 | 45 | 1 | 13 | |
| GSE47630 | CYTH2 | 9266 | 9 | 6 | 25 | |
| GSE54993 | CYTH2 | 9266 | 17 | 4 | 49 | |
| GSE54994 | CYTH2 | 9266 | 4 | 14 | 35 | |
| GSE60625 | CYTH2 | 9266 | 9 | 0 | 2 | |
| GSE74703 | CYTH2 | 9266 | 4 | 7 | 25 | |
| GSE74704 | CYTH2 | 9266 | 4 | 1 | 15 | |
| TCGA | CYTH2 | 9266 | 14 | 18 | 64 |
Total number of gains: 118; Total number of losses: 69; Total Number of normals: 301.
Somatic mutations of CYTH2:
Generating mutation plots.
Highly correlated genes for CYTH2:
Showing top 20/580 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYTH2 | ZNF33A | 0.816716 | 3 | 0 | 3 |
| CYTH2 | TMCO4 | 0.794232 | 3 | 0 | 3 |
| CYTH2 | LCOR | 0.777623 | 3 | 0 | 3 |
| CYTH2 | GGA3 | 0.776112 | 3 | 0 | 3 |
| CYTH2 | C2orf76 | 0.767196 | 3 | 0 | 3 |
| CYTH2 | CLYBL | 0.757737 | 3 | 0 | 3 |
| CYTH2 | SLC25A27 | 0.747953 | 3 | 0 | 3 |
| CYTH2 | TRIM56 | 0.745544 | 3 | 0 | 3 |
| CYTH2 | ZNF776 | 0.742954 | 3 | 0 | 3 |
| CYTH2 | ZNF529 | 0.741611 | 3 | 0 | 3 |
| CYTH2 | HSDL2 | 0.733769 | 3 | 0 | 3 |
| CYTH2 | ZNF70 | 0.727977 | 3 | 0 | 3 |
| CYTH2 | KIAA2026 | 0.72057 | 3 | 0 | 3 |
| CYTH2 | MLLT1 | 0.71579 | 3 | 0 | 3 |
| CYTH2 | BCLAF1 | 0.71497 | 3 | 0 | 3 |
| CYTH2 | C5orf51 | 0.713373 | 3 | 0 | 3 |
| CYTH2 | ZNF383 | 0.712676 | 4 | 0 | 4 |
| CYTH2 | ARHGAP35 | 0.711944 | 4 | 0 | 3 |
| CYTH2 | VRK3 | 0.708462 | 4 | 0 | 3 |
| CYTH2 | ZSCAN16 | 0.706678 | 3 | 0 | 3 |
For details and further investigation, click here
