| Full name: transmembrane and coiled-coil domains 4 | Alias Symbol: DKFZp686C23231 | ||
| Type: protein-coding gene | Cytoband: 1p36.13 | ||
| Entrez ID: 255104 | HGNC ID: HGNC:27393 | Ensembl Gene: ENSG00000162542 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMCO4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMCO4 | 255104 | 227007_at | 0.0206 | 0.9796 | |
| GSE26886 | TMCO4 | 255104 | 227007_at | -0.6508 | 0.0429 | |
| GSE45670 | TMCO4 | 255104 | 227007_at | -0.1807 | 0.4843 | |
| GSE53622 | TMCO4 | 255104 | 85630 | -0.3985 | 0.0001 | |
| GSE53624 | TMCO4 | 255104 | 85630 | -0.6638 | 0.0000 | |
| GSE63941 | TMCO4 | 255104 | 227007_at | -0.0875 | 0.8801 | |
| GSE77861 | TMCO4 | 255104 | 227007_at | -0.6101 | 0.0028 | |
| GSE97050 | TMCO4 | 255104 | A_23_P158277 | -0.1364 | 0.5313 | |
| SRP007169 | TMCO4 | 255104 | RNAseq | -3.0893 | 0.0000 | |
| SRP008496 | TMCO4 | 255104 | RNAseq | -1.9724 | 0.0000 | |
| SRP064894 | TMCO4 | 255104 | RNAseq | -0.7531 | 0.0010 | |
| SRP133303 | TMCO4 | 255104 | RNAseq | -0.5497 | 0.0096 | |
| SRP159526 | TMCO4 | 255104 | RNAseq | -1.0541 | 0.0039 | |
| SRP193095 | TMCO4 | 255104 | RNAseq | -0.6133 | 0.0003 | |
| SRP219564 | TMCO4 | 255104 | RNAseq | -0.3226 | 0.2294 | |
| TCGA | TMCO4 | 255104 | RNAseq | -0.2477 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by TMCO4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMCO4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMCO4 | 255104 | 0 | 5 | 25 | |
| GSE20123 | TMCO4 | 255104 | 0 | 4 | 26 | |
| GSE43470 | TMCO4 | 255104 | 0 | 8 | 35 | |
| GSE46452 | TMCO4 | 255104 | 5 | 1 | 53 | |
| GSE47630 | TMCO4 | 255104 | 8 | 3 | 29 | |
| GSE54993 | TMCO4 | 255104 | 3 | 1 | 66 | |
| GSE54994 | TMCO4 | 255104 | 11 | 4 | 38 | |
| GSE60625 | TMCO4 | 255104 | 0 | 0 | 11 | |
| GSE74703 | TMCO4 | 255104 | 0 | 5 | 31 | |
| GSE74704 | TMCO4 | 255104 | 0 | 0 | 20 | |
| TCGA | TMCO4 | 255104 | 10 | 22 | 64 |
Total number of gains: 37; Total number of losses: 53; Total Number of normals: 398.
Somatic mutations of TMCO4:
Generating mutation plots.
Highly correlated genes for TMCO4:
Showing top 20/918 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMCO4 | LCOR | 0.833135 | 3 | 0 | 3 |
| TMCO4 | PPP1R11 | 0.808918 | 3 | 0 | 3 |
| TMCO4 | ZNF506 | 0.796699 | 4 | 0 | 4 |
| TMCO4 | CYTH2 | 0.794232 | 3 | 0 | 3 |
| TMCO4 | ZSCAN12 | 0.789951 | 3 | 0 | 3 |
| TMCO4 | ZNF432 | 0.789795 | 3 | 0 | 3 |
| TMCO4 | PACRGL | 0.787001 | 3 | 0 | 3 |
| TMCO4 | LRRC41 | 0.784692 | 3 | 0 | 3 |
| TMCO4 | TOPORS | 0.783764 | 3 | 0 | 3 |
| TMCO4 | EPB41 | 0.779505 | 4 | 0 | 4 |
| TMCO4 | C5orf51 | 0.778946 | 3 | 0 | 3 |
| TMCO4 | GPBP1 | 0.777617 | 3 | 0 | 3 |
| TMCO4 | GCDH | 0.777022 | 3 | 0 | 3 |
| TMCO4 | HEMK1 | 0.77182 | 3 | 0 | 3 |
| TMCO4 | TBC1D20 | 0.765446 | 3 | 0 | 3 |
| TMCO4 | HDHD2 | 0.763843 | 4 | 0 | 4 |
| TMCO4 | EPB41L4A | 0.752542 | 3 | 0 | 3 |
| TMCO4 | ZNF606 | 0.750865 | 3 | 0 | 3 |
| TMCO4 | ZNF717 | 0.749103 | 4 | 0 | 4 |
| TMCO4 | FBXL3 | 0.744811 | 3 | 0 | 3 |
For details and further investigation, click here
