| Full name: zinc finger protein 70 | Alias Symbol: Cos17|MGC48959 | ||
| Type: protein-coding gene | Cytoband: 22q11.23 | ||
| Entrez ID: 7621 | HGNC ID: HGNC:13140 | Ensembl Gene: ENSG00000187792 | OMIM ID: 194544 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF70:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF70 | 7621 | 1554578_at | -0.0002 | 0.9994 | |
| GSE26886 | ZNF70 | 7621 | 1554578_at | -0.0347 | 0.8006 | |
| GSE45670 | ZNF70 | 7621 | 1554578_at | 0.0132 | 0.8857 | |
| GSE53622 | ZNF70 | 7621 | 159904 | 0.1832 | 0.0891 | |
| GSE53624 | ZNF70 | 7621 | 159904 | 0.2490 | 0.1128 | |
| GSE63941 | ZNF70 | 7621 | 1554578_at | -0.0577 | 0.6713 | |
| GSE77861 | ZNF70 | 7621 | 1554578_at | -0.2017 | 0.0251 | |
| GSE97050 | ZNF70 | 7621 | A_24_P941625 | -0.1455 | 0.5017 | |
| SRP007169 | ZNF70 | 7621 | RNAseq | 1.5400 | 0.0016 | |
| SRP008496 | ZNF70 | 7621 | RNAseq | 1.4657 | 0.0007 | |
| SRP064894 | ZNF70 | 7621 | RNAseq | 0.5315 | 0.0023 | |
| SRP133303 | ZNF70 | 7621 | RNAseq | 0.0894 | 0.5888 | |
| SRP159526 | ZNF70 | 7621 | RNAseq | 0.9307 | 0.0003 | |
| SRP193095 | ZNF70 | 7621 | RNAseq | 0.4545 | 0.0006 | |
| SRP219564 | ZNF70 | 7621 | RNAseq | 0.6074 | 0.0995 | |
| TCGA | ZNF70 | 7621 | RNAseq | -0.1848 | 0.0170 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ZNF70 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF70:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF70 | 7621 | 5 | 7 | 18 | |
| GSE20123 | ZNF70 | 7621 | 5 | 6 | 19 | |
| GSE43470 | ZNF70 | 7621 | 3 | 6 | 34 | |
| GSE46452 | ZNF70 | 7621 | 32 | 1 | 26 | |
| GSE47630 | ZNF70 | 7621 | 8 | 5 | 27 | |
| GSE54993 | ZNF70 | 7621 | 3 | 6 | 61 | |
| GSE54994 | ZNF70 | 7621 | 11 | 7 | 35 | |
| GSE60625 | ZNF70 | 7621 | 5 | 0 | 6 | |
| GSE74703 | ZNF70 | 7621 | 3 | 5 | 28 | |
| GSE74704 | ZNF70 | 7621 | 2 | 3 | 15 | |
| TCGA | ZNF70 | 7621 | 26 | 15 | 55 |
Total number of gains: 103; Total number of losses: 61; Total Number of normals: 324.
Somatic mutations of ZNF70:
Generating mutation plots.
Highly correlated genes for ZNF70:
Showing top 20/183 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF70 | PI4K2A | 0.795175 | 3 | 0 | 3 |
| ZNF70 | MPP5 | 0.785626 | 3 | 0 | 3 |
| ZNF70 | DAAM1 | 0.772364 | 3 | 0 | 3 |
| ZNF70 | ZNF436 | 0.768858 | 3 | 0 | 3 |
| ZNF70 | RB1 | 0.765202 | 3 | 0 | 3 |
| ZNF70 | PRKAR2A | 0.752481 | 3 | 0 | 3 |
| ZNF70 | DOK4 | 0.750244 | 3 | 0 | 3 |
| ZNF70 | TMEM19 | 0.744416 | 3 | 0 | 3 |
| ZNF70 | LARS2 | 0.742931 | 3 | 0 | 3 |
| ZNF70 | AHCYL2 | 0.739213 | 3 | 0 | 3 |
| ZNF70 | MORC3 | 0.734182 | 3 | 0 | 3 |
| ZNF70 | CPT2 | 0.733709 | 3 | 0 | 3 |
| ZNF70 | ERI2 | 0.732738 | 3 | 0 | 3 |
| ZNF70 | XPO4 | 0.732504 | 3 | 0 | 3 |
| ZNF70 | ACBD5 | 0.731957 | 3 | 0 | 3 |
| ZNF70 | ZNF627 | 0.731702 | 3 | 0 | 3 |
| ZNF70 | ABI1 | 0.729662 | 3 | 0 | 3 |
| ZNF70 | RAB3D | 0.729568 | 3 | 0 | 3 |
| ZNF70 | CYTH2 | 0.727977 | 3 | 0 | 3 |
| ZNF70 | EIF4E | 0.725372 | 3 | 0 | 3 |
For details and further investigation, click here
