| Full name: chromosome 2 open reading frame 76 | Alias Symbol: MGC104437|LOC130355|AIM29 | ||
| Type: protein-coding gene | Cytoband: 2q14.2 | ||
| Entrez ID: 130355 | HGNC ID: HGNC:27017 | Ensembl Gene: ENSG00000186132 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C2orf76:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C2orf76 | 130355 | 227840_at | 0.1875 | 0.7819 | |
| GSE26886 | C2orf76 | 130355 | 227840_at | -0.0102 | 0.9778 | |
| GSE45670 | C2orf76 | 130355 | 227840_at | -0.1400 | 0.4281 | |
| GSE53622 | C2orf76 | 130355 | 3215 | -0.1220 | 0.3274 | |
| GSE53624 | C2orf76 | 130355 | 3215 | -0.2283 | 0.0016 | |
| GSE63941 | C2orf76 | 130355 | 227840_at | -0.5229 | 0.4733 | |
| GSE77861 | C2orf76 | 130355 | 227840_at | -0.3166 | 0.1695 | |
| GSE97050 | C2orf76 | 130355 | A_23_P39542 | -0.0070 | 0.9841 | |
| SRP007169 | C2orf76 | 130355 | RNAseq | -0.6320 | 0.2310 | |
| SRP008496 | C2orf76 | 130355 | RNAseq | -0.5747 | 0.1051 | |
| SRP064894 | C2orf76 | 130355 | RNAseq | -0.2549 | 0.2203 | |
| SRP133303 | C2orf76 | 130355 | RNAseq | -0.2150 | 0.2488 | |
| SRP159526 | C2orf76 | 130355 | RNAseq | 0.1131 | 0.6796 | |
| SRP193095 | C2orf76 | 130355 | RNAseq | -0.2626 | 0.1809 | |
| SRP219564 | C2orf76 | 130355 | RNAseq | -0.7440 | 0.0645 | |
| TCGA | C2orf76 | 130355 | RNAseq | 0.0856 | 0.4986 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C2orf76 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C2orf76:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C2orf76 | 130355 | 6 | 1 | 23 | |
| GSE20123 | C2orf76 | 130355 | 6 | 1 | 23 | |
| GSE43470 | C2orf76 | 130355 | 3 | 1 | 39 | |
| GSE46452 | C2orf76 | 130355 | 1 | 4 | 54 | |
| GSE47630 | C2orf76 | 130355 | 6 | 0 | 34 | |
| GSE54993 | C2orf76 | 130355 | 0 | 6 | 64 | |
| GSE54994 | C2orf76 | 130355 | 11 | 0 | 42 | |
| GSE60625 | C2orf76 | 130355 | 0 | 3 | 8 | |
| GSE74703 | C2orf76 | 130355 | 3 | 1 | 32 | |
| GSE74704 | C2orf76 | 130355 | 3 | 1 | 16 | |
| TCGA | C2orf76 | 130355 | 32 | 6 | 58 |
Total number of gains: 71; Total number of losses: 24; Total Number of normals: 393.
Somatic mutations of C2orf76:
Generating mutation plots.
Highly correlated genes for C2orf76:
Showing top 20/187 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C2orf76 | ZNF268 | 0.799695 | 3 | 0 | 3 |
| C2orf76 | PSEN1 | 0.799347 | 3 | 0 | 3 |
| C2orf76 | TBC1D22B | 0.795166 | 3 | 0 | 3 |
| C2orf76 | ZNF274 | 0.781636 | 4 | 0 | 4 |
| C2orf76 | TRAPPC6B | 0.780317 | 3 | 0 | 3 |
| C2orf76 | PPM1A | 0.769839 | 3 | 0 | 3 |
| C2orf76 | BRWD1 | 0.769034 | 3 | 0 | 3 |
| C2orf76 | CYTH2 | 0.767196 | 3 | 0 | 3 |
| C2orf76 | STYX | 0.76525 | 3 | 0 | 3 |
| C2orf76 | HECTD3 | 0.760859 | 3 | 0 | 3 |
| C2orf76 | SCFD1 | 0.756764 | 3 | 0 | 3 |
| C2orf76 | PCGF6 | 0.755957 | 3 | 0 | 3 |
| C2orf76 | ZNF140 | 0.752844 | 3 | 0 | 3 |
| C2orf76 | LRP11 | 0.751604 | 3 | 0 | 3 |
| C2orf76 | ATP6V1G1 | 0.750165 | 3 | 0 | 3 |
| C2orf76 | FBXO8 | 0.750086 | 3 | 0 | 3 |
| C2orf76 | TMEM115 | 0.745383 | 3 | 0 | 3 |
| C2orf76 | HERC4 | 0.744563 | 4 | 0 | 4 |
| C2orf76 | BTBD7 | 0.741315 | 3 | 0 | 3 |
| C2orf76 | MED23 | 0.740888 | 3 | 0 | 3 |
For details and further investigation, click here
