| Full name: potassium voltage-gated channel subfamily A member 6 | Alias Symbol: Kv1.6|HBK2|PPP1R96 | ||
| Type: protein-coding gene | Cytoband: 12p13.32 | ||
| Entrez ID: 3742 | HGNC ID: HGNC:6225 | Ensembl Gene: ENSG00000151079 | OMIM ID: 176257 |
| Drug and gene relationship at DGIdb | |||
Expression of KCNA6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KCNA6 | 3742 | 1553347_s_at | 0.1350 | 0.5775 | |
| GSE26886 | KCNA6 | 3742 | 1553347_s_at | -0.2000 | 0.1033 | |
| GSE45670 | KCNA6 | 3742 | 1553347_s_at | 0.0234 | 0.8416 | |
| GSE63941 | KCNA6 | 3742 | 1553347_s_at | -0.0584 | 0.7713 | |
| GSE77861 | KCNA6 | 3742 | 1553347_s_at | -0.1624 | 0.0769 | |
| GSE97050 | KCNA6 | A_19_P00810465 | -0.1510 | 0.6801 | ||
| TCGA | KCNA6 | 3742 | RNAseq | -1.2370 | 0.0141 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by KCNA6 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of KCNA6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KCNA6 | 3742 | 6 | 4 | 20 | |
| GSE20123 | KCNA6 | 3742 | 6 | 4 | 20 | |
| GSE43470 | KCNA6 | 3742 | 9 | 3 | 31 | |
| GSE46452 | KCNA6 | 3742 | 10 | 1 | 48 | |
| GSE47630 | KCNA6 | 3742 | 12 | 2 | 26 | |
| GSE54993 | KCNA6 | 3742 | 1 | 10 | 59 | |
| GSE54994 | KCNA6 | 3742 | 10 | 2 | 41 | |
| GSE60625 | KCNA6 | 3742 | 0 | 1 | 10 | |
| GSE74703 | KCNA6 | 3742 | 8 | 2 | 26 | |
| GSE74704 | KCNA6 | 3742 | 4 | 2 | 14 | |
| TCGA | KCNA6 | 3742 | 40 | 6 | 50 |
Total number of gains: 106; Total number of losses: 37; Total Number of normals: 345.
Somatic mutations of KCNA6:
Generating mutation plots.
Highly correlated genes for KCNA6:
Showing top 20/61 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KCNA6 | THPO | 0.770419 | 3 | 0 | 3 |
| KCNA6 | LHFPL5 | 0.720952 | 3 | 0 | 3 |
| KCNA6 | SLC12A3 | 0.716001 | 3 | 0 | 3 |
| KCNA6 | DAO | 0.708166 | 3 | 0 | 3 |
| KCNA6 | FFAR1 | 0.707693 | 3 | 0 | 3 |
| KCNA6 | CALML6 | 0.705986 | 3 | 0 | 3 |
| KCNA6 | OR10H1 | 0.702988 | 4 | 0 | 3 |
| KCNA6 | HHIP | 0.702575 | 3 | 0 | 3 |
| KCNA6 | WFIKKN2 | 0.696719 | 3 | 0 | 3 |
| KCNA6 | OR2C3 | 0.691255 | 3 | 0 | 3 |
| KCNA6 | CCL25 | 0.690359 | 3 | 0 | 3 |
| KCNA6 | SUN5 | 0.684151 | 5 | 0 | 4 |
| KCNA6 | ZNF705G | 0.678335 | 3 | 0 | 3 |
| KCNA6 | C1QTNF6 | 0.677601 | 3 | 0 | 3 |
| KCNA6 | ADAMTS7 | 0.67283 | 3 | 0 | 3 |
| KCNA6 | CD300LG | 0.669248 | 4 | 0 | 4 |
| KCNA6 | UROC1 | 0.66487 | 3 | 0 | 3 |
| KCNA6 | CCDC157 | 0.662838 | 3 | 0 | 3 |
| KCNA6 | SHOX2 | 0.660288 | 3 | 0 | 3 |
| KCNA6 | CCDC62 | 0.653022 | 3 | 0 | 3 |
For details and further investigation, click here
