| Full name: LDL receptor related protein 5 like | Alias Symbol: DKFZp434O0213 | ||
| Type: protein-coding gene | Cytoband: 22q11.23 | ||
| Entrez ID: 91355 | HGNC ID: HGNC:25323 | Ensembl Gene: ENSG00000100068 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRP5L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRP5L | 91355 | 214873_at | 0.3853 | 0.3877 | |
| GSE20347 | LRP5L | 91355 | 214873_at | 0.2110 | 0.0221 | |
| GSE23400 | LRP5L | 91355 | 214873_at | 0.0817 | 0.0001 | |
| GSE26886 | LRP5L | 91355 | 214873_at | 1.1026 | 0.0000 | |
| GSE29001 | LRP5L | 91355 | 214873_at | 0.2701 | 0.1386 | |
| GSE38129 | LRP5L | 91355 | 214873_at | 0.2416 | 0.0027 | |
| GSE45670 | LRP5L | 91355 | 214873_at | 0.0255 | 0.8941 | |
| GSE53622 | LRP5L | 91355 | 171974 | 0.3531 | 0.0014 | |
| GSE53624 | LRP5L | 91355 | 171974 | 0.2984 | 0.0003 | |
| GSE63941 | LRP5L | 91355 | 214873_at | 0.1292 | 0.6719 | |
| GSE77861 | LRP5L | 91355 | 214873_at | 0.0828 | 0.3755 | |
| GSE97050 | LRP5L | 91355 | A_33_P3326545 | -0.0782 | 0.8638 | |
| SRP007169 | LRP5L | 91355 | RNAseq | 0.9983 | 0.2373 | |
| SRP064894 | LRP5L | 91355 | RNAseq | 0.5729 | 0.0323 | |
| SRP133303 | LRP5L | 91355 | RNAseq | -0.0814 | 0.8044 | |
| SRP193095 | LRP5L | 91355 | RNAseq | 0.7905 | 0.0001 | |
| SRP219564 | LRP5L | 91355 | RNAseq | 0.8219 | 0.0203 | |
| TCGA | LRP5L | 91355 | RNAseq | -0.1144 | 0.2430 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by LRP5L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRP5L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRP5L | 91355 | 4 | 6 | 20 | |
| GSE20123 | LRP5L | 91355 | 4 | 5 | 21 | |
| GSE43470 | LRP5L | 91355 | 3 | 5 | 35 | |
| GSE46452 | LRP5L | 91355 | 31 | 1 | 27 | |
| GSE47630 | LRP5L | 91355 | 8 | 5 | 27 | |
| GSE54993 | LRP5L | 91355 | 3 | 6 | 61 | |
| GSE54994 | LRP5L | 91355 | 11 | 7 | 35 | |
| GSE60625 | LRP5L | 91355 | 5 | 0 | 6 | |
| GSE74703 | LRP5L | 91355 | 3 | 4 | 29 | |
| GSE74704 | LRP5L | 91355 | 1 | 3 | 16 | |
| TCGA | LRP5L | 91355 | 26 | 14 | 56 |
Total number of gains: 99; Total number of losses: 56; Total Number of normals: 333.
Somatic mutations of LRP5L:
Generating mutation plots.
Highly correlated genes for LRP5L:
Showing top 20/641 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRP5L | FIP1L1 | 0.792169 | 3 | 0 | 3 |
| LRP5L | FOXJ2 | 0.781761 | 3 | 0 | 3 |
| LRP5L | CAMKK1 | 0.78041 | 3 | 0 | 3 |
| LRP5L | PIGX | 0.772716 | 3 | 0 | 3 |
| LRP5L | WBP11 | 0.771764 | 3 | 0 | 3 |
| LRP5L | TOP1MT | 0.763923 | 3 | 0 | 3 |
| LRP5L | FXR2 | 0.759879 | 3 | 0 | 3 |
| LRP5L | DDX55 | 0.755475 | 3 | 0 | 3 |
| LRP5L | SPSB2 | 0.75271 | 3 | 0 | 3 |
| LRP5L | UHRF1BP1 | 0.750304 | 3 | 0 | 3 |
| LRP5L | CWC22 | 0.7471 | 3 | 0 | 3 |
| LRP5L | CHIC1 | 0.74699 | 3 | 0 | 3 |
| LRP5L | MED30 | 0.746975 | 3 | 0 | 3 |
| LRP5L | DBN1 | 0.745324 | 4 | 0 | 4 |
| LRP5L | IMMP1L | 0.74443 | 3 | 0 | 3 |
| LRP5L | VEZT | 0.744006 | 3 | 0 | 3 |
| LRP5L | DHX37 | 0.736475 | 3 | 0 | 3 |
| LRP5L | TBC1D8 | 0.735545 | 3 | 0 | 3 |
| LRP5L | ACBD6 | 0.734179 | 4 | 0 | 3 |
| LRP5L | TMEM63B | 0.733362 | 3 | 0 | 3 |
For details and further investigation, click here
