| Full name: gametogenetin binding protein 2 | Alias Symbol: ZFP403|LZK1|FLJ22561|FLJ21230|DIF-3|DIF3 | ||
| Type: protein-coding gene | Cytoband: 17q12 | ||
| Entrez ID: 79893 | HGNC ID: HGNC:19357 | Ensembl Gene: ENSG00000278311 | OMIM ID: 612275 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of GGNBP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GGNBP2 | 79893 | 218079_s_at | 0.1820 | 0.3821 | |
| GSE20347 | GGNBP2 | 79893 | 218079_s_at | 0.1304 | 0.2688 | |
| GSE23400 | GGNBP2 | 79893 | 218079_s_at | 0.2706 | 0.0000 | |
| GSE26886 | GGNBP2 | 79893 | 218079_s_at | -0.0786 | 0.7224 | |
| GSE29001 | GGNBP2 | 79893 | 218079_s_at | 0.1081 | 0.5462 | |
| GSE38129 | GGNBP2 | 79893 | 218079_s_at | 0.1121 | 0.1503 | |
| GSE45670 | GGNBP2 | 79893 | 218079_s_at | -0.0614 | 0.6035 | |
| GSE53622 | GGNBP2 | 79893 | 77695 | -0.1584 | 0.0100 | |
| GSE53624 | GGNBP2 | 79893 | 77695 | -0.1235 | 0.0813 | |
| GSE63941 | GGNBP2 | 79893 | 218079_s_at | -0.8553 | 0.0066 | |
| GSE77861 | GGNBP2 | 79893 | 218079_s_at | 0.5495 | 0.0015 | |
| GSE97050 | GGNBP2 | 79893 | A_23_P38408 | -0.3630 | 0.1892 | |
| SRP007169 | GGNBP2 | 79893 | RNAseq | 0.1408 | 0.6932 | |
| SRP008496 | GGNBP2 | 79893 | RNAseq | 0.3463 | 0.1245 | |
| SRP064894 | GGNBP2 | 79893 | RNAseq | -0.0105 | 0.9337 | |
| SRP133303 | GGNBP2 | 79893 | RNAseq | -0.0294 | 0.8002 | |
| SRP159526 | GGNBP2 | 79893 | RNAseq | -0.0423 | 0.8381 | |
| SRP193095 | GGNBP2 | 79893 | RNAseq | -0.0780 | 0.1867 | |
| SRP219564 | GGNBP2 | 79893 | RNAseq | -0.1732 | 0.3775 | |
| TCGA | GGNBP2 | 79893 | RNAseq | -0.0386 | 0.3980 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GGNBP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GGNBP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GGNBP2 | 79893 | 5 | 1 | 24 | |
| GSE20123 | GGNBP2 | 79893 | 5 | 1 | 24 | |
| GSE43470 | GGNBP2 | 79893 | 1 | 2 | 40 | |
| GSE46452 | GGNBP2 | 79893 | 34 | 0 | 25 | |
| GSE47630 | GGNBP2 | 79893 | 8 | 1 | 31 | |
| GSE54993 | GGNBP2 | 79893 | 3 | 3 | 64 | |
| GSE54994 | GGNBP2 | 79893 | 8 | 6 | 39 | |
| GSE60625 | GGNBP2 | 79893 | 4 | 0 | 7 | |
| GSE74703 | GGNBP2 | 79893 | 1 | 1 | 34 | |
| GSE74704 | GGNBP2 | 79893 | 3 | 1 | 16 | |
| TCGA | GGNBP2 | 79893 | 20 | 9 | 67 |
Total number of gains: 92; Total number of losses: 25; Total Number of normals: 371.
Somatic mutations of GGNBP2:
Generating mutation plots.
Highly correlated genes for GGNBP2:
Showing top 20/403 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GGNBP2 | SLC41A1 | 0.80488 | 3 | 0 | 3 |
| GGNBP2 | YWHAG | 0.7978 | 3 | 0 | 3 |
| GGNBP2 | CERS5 | 0.786075 | 3 | 0 | 3 |
| GGNBP2 | EIF5A2 | 0.773931 | 3 | 0 | 3 |
| GGNBP2 | TRIM59 | 0.763592 | 3 | 0 | 3 |
| GGNBP2 | ZNF518B | 0.758752 | 3 | 0 | 3 |
| GGNBP2 | TMEM138 | 0.758668 | 3 | 0 | 3 |
| GGNBP2 | ZNF317 | 0.755567 | 3 | 0 | 3 |
| GGNBP2 | ABL2 | 0.741546 | 4 | 0 | 4 |
| GGNBP2 | AMMECR1L | 0.73915 | 4 | 0 | 4 |
| GGNBP2 | SSR3 | 0.731871 | 3 | 0 | 3 |
| GGNBP2 | SF1 | 0.727711 | 4 | 0 | 3 |
| GGNBP2 | KDSR | 0.727576 | 3 | 0 | 3 |
| GGNBP2 | TWSG1 | 0.727559 | 3 | 0 | 3 |
| GGNBP2 | DBN1 | 0.726746 | 3 | 0 | 3 |
| GGNBP2 | PXN | 0.718133 | 3 | 0 | 3 |
| GGNBP2 | QSOX2 | 0.714708 | 3 | 0 | 3 |
| GGNBP2 | CIR1 | 0.713007 | 3 | 0 | 3 |
| GGNBP2 | FEZ2 | 0.712442 | 3 | 0 | 3 |
| GGNBP2 | CASK | 0.711831 | 3 | 0 | 3 |
For details and further investigation, click here
