| Full name: CDC42 effector protein 4 | Alias Symbol: CEP4|KAIA1777|BORG4|MGC3740|MGC17125 | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 23580 | HGNC ID: HGNC:17147 | Ensembl Gene: ENSG00000179604 | OMIM ID: 605468 |
| Drug and gene relationship at DGIdb | |||
Expression of CDC42EP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDC42EP4 | 23580 | 218062_x_at | 0.3610 | 0.4287 | |
| GSE20347 | CDC42EP4 | 23580 | 214721_x_at | 0.5426 | 0.0211 | |
| GSE23400 | CDC42EP4 | 23580 | 218062_x_at | 0.2979 | 0.0010 | |
| GSE26886 | CDC42EP4 | 23580 | 218062_x_at | 1.1023 | 0.0000 | |
| GSE29001 | CDC42EP4 | 23580 | 218062_x_at | 0.5126 | 0.0485 | |
| GSE38129 | CDC42EP4 | 23580 | 218062_x_at | 0.2935 | 0.0677 | |
| GSE45670 | CDC42EP4 | 23580 | 214721_x_at | 0.1818 | 0.5534 | |
| GSE53622 | CDC42EP4 | 23580 | 84081 | 0.1406 | 0.1702 | |
| GSE53624 | CDC42EP4 | 23580 | 84081 | 0.3234 | 0.0128 | |
| GSE63941 | CDC42EP4 | 23580 | 218062_x_at | 0.2917 | 0.5807 | |
| GSE77861 | CDC42EP4 | 23580 | 214721_x_at | 0.9820 | 0.0148 | |
| GSE97050 | CDC42EP4 | 23580 | A_23_P66891 | 0.2131 | 0.6378 | |
| SRP007169 | CDC42EP4 | 23580 | RNAseq | 0.4063 | 0.4070 | |
| SRP008496 | CDC42EP4 | 23580 | RNAseq | 0.0358 | 0.9192 | |
| SRP064894 | CDC42EP4 | 23580 | RNAseq | 0.0589 | 0.7991 | |
| SRP133303 | CDC42EP4 | 23580 | RNAseq | 0.4351 | 0.0832 | |
| SRP159526 | CDC42EP4 | 23580 | RNAseq | 0.2827 | 0.5557 | |
| SRP193095 | CDC42EP4 | 23580 | RNAseq | 0.7710 | 0.0001 | |
| SRP219564 | CDC42EP4 | 23580 | RNAseq | 0.1662 | 0.6282 | |
| TCGA | CDC42EP4 | 23580 | RNAseq | -0.0049 | 0.9361 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CDC42EP4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDC42EP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDC42EP4 | 23580 | 3 | 2 | 25 | |
| GSE20123 | CDC42EP4 | 23580 | 3 | 2 | 25 | |
| GSE43470 | CDC42EP4 | 23580 | 6 | 3 | 34 | |
| GSE46452 | CDC42EP4 | 23580 | 33 | 0 | 26 | |
| GSE47630 | CDC42EP4 | 23580 | 8 | 1 | 31 | |
| GSE54993 | CDC42EP4 | 23580 | 2 | 5 | 63 | |
| GSE54994 | CDC42EP4 | 23580 | 10 | 4 | 39 | |
| GSE60625 | CDC42EP4 | 23580 | 6 | 0 | 5 | |
| GSE74703 | CDC42EP4 | 23580 | 6 | 1 | 29 | |
| GSE74704 | CDC42EP4 | 23580 | 3 | 2 | 15 | |
| TCGA | CDC42EP4 | 23580 | 32 | 10 | 54 |
Total number of gains: 112; Total number of losses: 30; Total Number of normals: 346.
Somatic mutations of CDC42EP4:
Generating mutation plots.
Highly correlated genes for CDC42EP4:
Showing top 20/1089 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDC42EP4 | CERS5 | 0.832278 | 3 | 0 | 3 |
| CDC42EP4 | SLC39A13 | 0.808085 | 4 | 0 | 4 |
| CDC42EP4 | GZF1 | 0.75845 | 3 | 0 | 3 |
| CDC42EP4 | U2AF2 | 0.753581 | 3 | 0 | 3 |
| CDC42EP4 | ZNF362 | 0.752587 | 3 | 0 | 3 |
| CDC42EP4 | THEM4 | 0.749954 | 3 | 0 | 3 |
| CDC42EP4 | DCHS2 | 0.74991 | 3 | 0 | 3 |
| CDC42EP4 | COPRS | 0.749488 | 3 | 0 | 3 |
| CDC42EP4 | PKN3 | 0.747122 | 3 | 0 | 3 |
| CDC42EP4 | ZNF827 | 0.746355 | 4 | 0 | 4 |
| CDC42EP4 | CDKN1C | 0.744463 | 3 | 0 | 3 |
| CDC42EP4 | GRAMD1A | 0.743945 | 4 | 0 | 4 |
| CDC42EP4 | NCKIPSD | 0.743602 | 3 | 0 | 3 |
| CDC42EP4 | UTP20 | 0.740078 | 3 | 0 | 3 |
| CDC42EP4 | NTPCR | 0.739401 | 3 | 0 | 3 |
| CDC42EP4 | DENND5B | 0.736129 | 3 | 0 | 3 |
| CDC42EP4 | TTC7B | 0.735763 | 4 | 0 | 4 |
| CDC42EP4 | MAP3K11 | 0.732695 | 3 | 0 | 3 |
| CDC42EP4 | GLIS2 | 0.728998 | 4 | 0 | 4 |
| CDC42EP4 | ZNF343 | 0.72892 | 3 | 0 | 3 |
For details and further investigation, click here
