| Full name: nanos C2HC-type zinc finger 3 | Alias Symbol: NANOS1L|NOS3|ZC2HC12C | ||
| Type: protein-coding gene | Cytoband: 19p13.13 | ||
| Entrez ID: 342977 | HGNC ID: HGNC:22048 | Ensembl Gene: ENSG00000187556 | OMIM ID: 608229 |
| Drug and gene relationship at DGIdb | |||
Expression of NANOS3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NANOS3 | 342977 | 240311_at | 0.0042 | 0.9934 | |
| GSE26886 | NANOS3 | 342977 | 240311_at | 0.2956 | 0.0180 | |
| GSE45670 | NANOS3 | 342977 | 240311_at | 0.0630 | 0.6020 | |
| GSE53622 | NANOS3 | 342977 | 49612 | 0.1584 | 0.0121 | |
| GSE53624 | NANOS3 | 342977 | 49612 | 0.0247 | 0.7687 | |
| GSE63941 | NANOS3 | 342977 | 240311_at | 0.0613 | 0.7251 | |
| GSE77861 | NANOS3 | 342977 | 240311_at | -0.1034 | 0.3488 | |
| GSE97050 | NANOS3 | 342977 | A_24_P703830 | -0.0638 | 0.8055 | |
| TCGA | NANOS3 | 342977 | RNAseq | 1.1841 | 0.0117 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NANOS3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NANOS3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NANOS3 | 342977 | 4 | 2 | 24 | |
| GSE20123 | NANOS3 | 342977 | 3 | 1 | 26 | |
| GSE43470 | NANOS3 | 342977 | 2 | 6 | 35 | |
| GSE46452 | NANOS3 | 342977 | 47 | 1 | 11 | |
| GSE47630 | NANOS3 | 342977 | 4 | 7 | 29 | |
| GSE54993 | NANOS3 | 342977 | 15 | 4 | 51 | |
| GSE54994 | NANOS3 | 342977 | 6 | 13 | 34 | |
| GSE60625 | NANOS3 | 342977 | 9 | 0 | 2 | |
| GSE74703 | NANOS3 | 342977 | 2 | 4 | 30 | |
| GSE74704 | NANOS3 | 342977 | 0 | 1 | 19 | |
| TCGA | NANOS3 | 342977 | 21 | 11 | 64 |
Total number of gains: 113; Total number of losses: 50; Total Number of normals: 325.
Somatic mutations of NANOS3:
Generating mutation plots.
Highly correlated genes for NANOS3:
Showing top 20/269 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NANOS3 | PLIN4 | 0.757523 | 3 | 0 | 3 |
| NANOS3 | MEIS3 | 0.741836 | 3 | 0 | 3 |
| NANOS3 | LINC00917 | 0.718329 | 4 | 0 | 4 |
| NANOS3 | C16orf86 | 0.716284 | 5 | 0 | 5 |
| NANOS3 | TNFRSF10C | 0.712745 | 4 | 0 | 4 |
| NANOS3 | GATA6 | 0.712258 | 3 | 0 | 3 |
| NANOS3 | PRDM8 | 0.709777 | 3 | 0 | 3 |
| NANOS3 | DCHS2 | 0.708734 | 3 | 0 | 3 |
| NANOS3 | TRNAU1AP | 0.708082 | 3 | 0 | 3 |
| NANOS3 | CDAN1 | 0.704608 | 3 | 0 | 3 |
| NANOS3 | BSN | 0.699177 | 3 | 0 | 3 |
| NANOS3 | SPEG | 0.689258 | 3 | 0 | 3 |
| NANOS3 | BARHL1 | 0.686715 | 5 | 0 | 5 |
| NANOS3 | REEP2 | 0.682912 | 5 | 0 | 4 |
| NANOS3 | JPH2 | 0.681252 | 3 | 0 | 3 |
| NANOS3 | NINJ1 | 0.677592 | 3 | 0 | 3 |
| NANOS3 | NUTM1 | 0.669939 | 4 | 0 | 4 |
| NANOS3 | NRL | 0.669128 | 4 | 0 | 4 |
| NANOS3 | PARD3B | 0.668765 | 4 | 0 | 3 |
| NANOS3 | TCP11L1 | 0.664822 | 5 | 0 | 4 |
For details and further investigation, click here
