| Full name: dynein axonemal heavy chain 11 | Alias Symbol: Dnahc11|DPL11|CILD7|DNAHC11|DNAHBL|DNHBL | ||
| Type: protein-coding gene | Cytoband: 7p15.3 | ||
| Entrez ID: 8701 | HGNC ID: HGNC:2942 | Ensembl Gene: ENSG00000105877 | OMIM ID: 603339 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAH11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAH11 | 8701 | 1553159_at | 0.1048 | 0.6978 | |
| GSE26886 | DNAH11 | 8701 | 1553159_at | 0.0889 | 0.4544 | |
| GSE45670 | DNAH11 | 8701 | 1553159_at | 0.0635 | 0.4855 | |
| GSE63941 | DNAH11 | 8701 | 1553159_at | 0.4362 | 0.1854 | |
| GSE77861 | DNAH11 | 8701 | 1553159_at | -0.0478 | 0.6553 | |
| GSE97050 | DNAH11 | 8701 | A_32_P19806 | 0.0211 | 0.9652 | |
| SRP007169 | DNAH11 | 8701 | RNAseq | 0.2867 | 0.7518 | |
| SRP133303 | DNAH11 | 8701 | RNAseq | 0.5073 | 0.1465 | |
| SRP159526 | DNAH11 | 8701 | RNAseq | -0.0269 | 0.9622 | |
| SRP193095 | DNAH11 | 8701 | RNAseq | -0.2085 | 0.5249 | |
| SRP219564 | DNAH11 | 8701 | RNAseq | -1.6014 | 0.0006 | |
| TCGA | DNAH11 | 8701 | RNAseq | 0.2716 | 0.5520 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DNAH11 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of DNAH11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAH11 | 8701 | 17 | 1 | 12 | |
| GSE20123 | DNAH11 | 8701 | 17 | 1 | 12 | |
| GSE43470 | DNAH11 | 8701 | 4 | 0 | 39 | |
| GSE46452 | DNAH11 | 8701 | 10 | 2 | 47 | |
| GSE47630 | DNAH11 | 8701 | 9 | 1 | 30 | |
| GSE54993 | DNAH11 | 8701 | 0 | 6 | 64 | |
| GSE54994 | DNAH11 | 8701 | 20 | 2 | 31 | |
| GSE60625 | DNAH11 | 8701 | 0 | 0 | 11 | |
| GSE74703 | DNAH11 | 8701 | 4 | 0 | 32 | |
| GSE74704 | DNAH11 | 8701 | 11 | 1 | 8 | |
| TCGA | DNAH11 | 8701 | 57 | 4 | 35 |
Total number of gains: 149; Total number of losses: 18; Total Number of normals: 321.
Somatic mutations of DNAH11:
Generating mutation plots.
Highly correlated genes for DNAH11:
Showing top 20/190 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAH11 | MAPRE3 | 0.795177 | 3 | 0 | 3 |
| DNAH11 | HDAC11 | 0.769582 | 3 | 0 | 3 |
| DNAH11 | PROX1 | 0.767561 | 3 | 0 | 3 |
| DNAH11 | FN3K | 0.760207 | 3 | 0 | 3 |
| DNAH11 | RGS3 | 0.753446 | 3 | 0 | 3 |
| DNAH11 | CATSPER1 | 0.75113 | 3 | 0 | 3 |
| DNAH11 | RARA | 0.750253 | 3 | 0 | 3 |
| DNAH11 | SERPINA5 | 0.73688 | 3 | 0 | 3 |
| DNAH11 | POLN | 0.733089 | 3 | 0 | 3 |
| DNAH11 | TMEM145 | 0.7301 | 3 | 0 | 3 |
| DNAH11 | RHOH | 0.725719 | 3 | 0 | 3 |
| DNAH11 | APBA1 | 0.723579 | 3 | 0 | 3 |
| DNAH11 | VWA1 | 0.721266 | 3 | 0 | 3 |
| DNAH11 | CD36 | 0.716697 | 3 | 0 | 3 |
| DNAH11 | ZNF683 | 0.71657 | 3 | 0 | 3 |
| DNAH11 | TEAD2 | 0.71538 | 3 | 0 | 3 |
| DNAH11 | GRIN3A | 0.714255 | 3 | 0 | 3 |
| DNAH11 | MAPK11 | 0.710446 | 3 | 0 | 3 |
| DNAH11 | MAST2 | 0.710344 | 3 | 0 | 3 |
| DNAH11 | PLEKHG2 | 0.703837 | 3 | 0 | 3 |
For details and further investigation, click here
