| Full name: WD repeat domain 62 | Alias Symbol: DKFZP434J046|FLJ33298 | ||
| Type: protein-coding gene | Cytoband: 19q13.12 | ||
| Entrez ID: 284403 | HGNC ID: HGNC:24502 | Ensembl Gene: ENSG00000075702 | OMIM ID: 613583 |
| Drug and gene relationship at DGIdb | |||
Expression of WDR62:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR62 | 284403 | 215218_s_at | 0.3742 | 0.0659 | |
| GSE20347 | WDR62 | 284403 | 215218_s_at | 0.1691 | 0.0494 | |
| GSE23400 | WDR62 | 284403 | 215218_s_at | 0.2883 | 0.0000 | |
| GSE26886 | WDR62 | 284403 | 215218_s_at | 0.4782 | 0.0001 | |
| GSE29001 | WDR62 | 284403 | 215218_s_at | 0.1519 | 0.3540 | |
| GSE38129 | WDR62 | 284403 | 215218_s_at | 0.2543 | 0.0016 | |
| GSE45670 | WDR62 | 284403 | 215218_s_at | 0.1949 | 0.0492 | |
| GSE63941 | WDR62 | 284403 | 215218_s_at | 0.4267 | 0.0178 | |
| GSE77861 | WDR62 | 284403 | 215218_s_at | 0.1103 | 0.5277 | |
| GSE97050 | WDR62 | 284403 | A_33_P3254606 | 0.3519 | 0.2909 | |
| SRP007169 | WDR62 | 284403 | RNAseq | 3.8279 | 0.0000 | |
| SRP064894 | WDR62 | 284403 | RNAseq | 1.8885 | 0.0000 | |
| SRP133303 | WDR62 | 284403 | RNAseq | 1.6065 | 0.0000 | |
| SRP159526 | WDR62 | 284403 | RNAseq | 2.2684 | 0.0000 | |
| SRP193095 | WDR62 | 284403 | RNAseq | 1.4577 | 0.0000 | |
| SRP219564 | WDR62 | 284403 | RNAseq | 1.8162 | 0.0024 | |
| TCGA | WDR62 | 284403 | RNAseq | 1.2206 | 0.0000 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by WDR62 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of WDR62:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR62 | 284403 | 8 | 4 | 18 | |
| GSE20123 | WDR62 | 284403 | 8 | 3 | 19 | |
| GSE43470 | WDR62 | 284403 | 3 | 7 | 33 | |
| GSE46452 | WDR62 | 284403 | 48 | 1 | 10 | |
| GSE47630 | WDR62 | 284403 | 9 | 5 | 26 | |
| GSE54993 | WDR62 | 284403 | 17 | 3 | 50 | |
| GSE54994 | WDR62 | 284403 | 6 | 9 | 38 | |
| GSE60625 | WDR62 | 284403 | 9 | 0 | 2 | |
| GSE74703 | WDR62 | 284403 | 3 | 4 | 29 | |
| GSE74704 | WDR62 | 284403 | 7 | 1 | 12 | |
| TCGA | WDR62 | 284403 | 22 | 10 | 64 |
Total number of gains: 140; Total number of losses: 47; Total Number of normals: 301.
Somatic mutations of WDR62:
Generating mutation plots.
Highly correlated genes for WDR62:
Showing top 20/606 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR62 | SLC16A10 | 0.729087 | 3 | 0 | 3 |
| WDR62 | RIMS4 | 0.724656 | 3 | 0 | 3 |
| WDR62 | CPT1C | 0.712934 | 3 | 0 | 3 |
| WDR62 | CD276 | 0.708281 | 3 | 0 | 3 |
| WDR62 | UBTD1 | 0.694266 | 3 | 0 | 3 |
| WDR62 | POLE4 | 0.694038 | 3 | 0 | 3 |
| WDR62 | MAPK4 | 0.689989 | 3 | 0 | 3 |
| WDR62 | SIPA1L3 | 0.684314 | 9 | 0 | 7 |
| WDR62 | FMNL3 | 0.68303 | 3 | 0 | 3 |
| WDR62 | ADAMTS2 | 0.677524 | 4 | 0 | 3 |
| WDR62 | MUC13 | 0.670179 | 3 | 0 | 3 |
| WDR62 | HAGLROS | 0.665413 | 3 | 0 | 3 |
| WDR62 | SSTR3 | 0.664532 | 5 | 0 | 5 |
| WDR62 | DHX37 | 0.661621 | 4 | 0 | 3 |
| WDR62 | NLE1 | 0.660592 | 3 | 0 | 3 |
| WDR62 | GINS2 | 0.658688 | 6 | 0 | 5 |
| WDR62 | DDN | 0.655444 | 4 | 0 | 4 |
| WDR62 | FBN3 | 0.653987 | 3 | 0 | 3 |
| WDR62 | APOBEC3B | 0.652202 | 4 | 0 | 4 |
| WDR62 | NOX1 | 0.649525 | 4 | 0 | 4 |
For details and further investigation, click here
