| Full name: NADPH oxidase organizer 1 | Alias Symbol: P41NOXA|P41NOXB|P41NOXC|SH3PXD5|SNX28 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 124056 | HGNC ID: HGNC:19404 | Ensembl Gene: ENSG00000196408 | OMIM ID: 611256 |
| Drug and gene relationship at DGIdb | |||
Expression of NOXO1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOXO1 | 124056 | 235329_at | 0.0863 | 0.8953 | |
| GSE26886 | NOXO1 | 124056 | 235329_at | 0.1163 | 0.2919 | |
| GSE45670 | NOXO1 | 124056 | 235329_at | -0.1735 | 0.1664 | |
| GSE63941 | NOXO1 | 124056 | 235329_at | 0.3292 | 0.2120 | |
| GSE77861 | NOXO1 | 124056 | 235329_at | -0.2299 | 0.1799 | |
| GSE97050 | NOXO1 | 124056 | A_33_P3333800 | -0.1080 | 0.6026 | |
| TCGA | NOXO1 | 124056 | RNAseq | 0.5943 | 0.0830 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NOXO1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NOXO1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOXO1 | 124056 | 5 | 5 | 20 | |
| GSE20123 | NOXO1 | 124056 | 5 | 4 | 21 | |
| GSE43470 | NOXO1 | 124056 | 4 | 7 | 32 | |
| GSE46452 | NOXO1 | 124056 | 38 | 1 | 20 | |
| GSE47630 | NOXO1 | 124056 | 13 | 6 | 21 | |
| GSE54993 | NOXO1 | 124056 | 3 | 5 | 62 | |
| GSE54994 | NOXO1 | 124056 | 5 | 9 | 39 | |
| GSE60625 | NOXO1 | 124056 | 4 | 0 | 7 | |
| GSE74703 | NOXO1 | 124056 | 4 | 5 | 27 | |
| GSE74704 | NOXO1 | 124056 | 3 | 2 | 15 | |
| TCGA | NOXO1 | 124056 | 19 | 14 | 63 |
Total number of gains: 103; Total number of losses: 58; Total Number of normals: 327.
Somatic mutations of NOXO1:
Generating mutation plots.
Highly correlated genes for NOXO1:
Showing top 20/258 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOXO1 | FMN2 | 0.788275 | 3 | 0 | 3 |
| NOXO1 | ALG12 | 0.734214 | 3 | 0 | 3 |
| NOXO1 | MYCN | 0.733212 | 3 | 0 | 3 |
| NOXO1 | HSPA4 | 0.733114 | 3 | 0 | 3 |
| NOXO1 | ESR2 | 0.72892 | 3 | 0 | 3 |
| NOXO1 | DCTN2 | 0.728472 | 3 | 0 | 3 |
| NOXO1 | PLD6 | 0.725658 | 3 | 0 | 3 |
| NOXO1 | EGLN2 | 0.707536 | 4 | 0 | 4 |
| NOXO1 | DHX32 | 0.701704 | 3 | 0 | 3 |
| NOXO1 | ARPC5L | 0.69877 | 3 | 0 | 3 |
| NOXO1 | CAMKK1 | 0.696029 | 3 | 0 | 3 |
| NOXO1 | ANO8 | 0.695763 | 3 | 0 | 3 |
| NOXO1 | ZBTB8OS | 0.69382 | 3 | 0 | 3 |
| NOXO1 | CALY | 0.692962 | 3 | 0 | 3 |
| NOXO1 | CINP | 0.692457 | 3 | 0 | 3 |
| NOXO1 | SLC46A2 | 0.688987 | 3 | 0 | 3 |
| NOXO1 | GPR37L1 | 0.684042 | 3 | 0 | 3 |
| NOXO1 | S1PR5 | 0.683533 | 3 | 0 | 3 |
| NOXO1 | HLA-DQB2 | 0.683054 | 3 | 0 | 3 |
| NOXO1 | AMER3 | 0.682848 | 3 | 0 | 3 |
For details and further investigation, click here
