| Full name: kallikrein related peptidase 14 | Alias Symbol: KLK-L6 | ||
| Type: protein-coding gene | Cytoband: 19q13.41 | ||
| Entrez ID: 43847 | HGNC ID: HGNC:6362 | Ensembl Gene: ENSG00000129437 | OMIM ID: 606135 |
| Drug and gene relationship at DGIdb | |||
Expression of KLK14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLK14 | 43847 | 220573_at | 0.2564 | 0.5495 | |
| GSE20347 | KLK14 | 43847 | 220573_at | 0.0585 | 0.7822 | |
| GSE23400 | KLK14 | 43847 | 220573_at | 0.0962 | 0.1291 | |
| GSE26886 | KLK14 | 43847 | 220573_at | 0.3490 | 0.0046 | |
| GSE29001 | KLK14 | 43847 | 220573_at | -0.0530 | 0.7797 | |
| GSE38129 | KLK14 | 43847 | 220573_at | -0.0347 | 0.8032 | |
| GSE45670 | KLK14 | 43847 | 220573_at | -0.0094 | 0.9361 | |
| GSE53622 | KLK14 | 43847 | 93728 | 1.3904 | 0.0000 | |
| GSE53624 | KLK14 | 43847 | 93728 | 0.9524 | 0.0000 | |
| GSE63941 | KLK14 | 43847 | 220573_at | 0.1234 | 0.5390 | |
| GSE77861 | KLK14 | 43847 | 220573_at | -0.1655 | 0.3058 | |
| GSE97050 | KLK14 | 43847 | A_33_P3417640 | 1.3015 | 0.2926 | |
| SRP133303 | KLK14 | 43847 | RNAseq | -0.1233 | 0.6937 | |
| SRP159526 | KLK14 | 43847 | RNAseq | 0.9064 | 0.1195 | |
| SRP219564 | KLK14 | 43847 | RNAseq | -0.5143 | 0.2656 | |
| TCGA | KLK14 | 43847 | RNAseq | 0.7490 | 0.1714 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by KLK14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLK14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLK14 | 43847 | 3 | 4 | 23 | |
| GSE20123 | KLK14 | 43847 | 3 | 3 | 24 | |
| GSE43470 | KLK14 | 43847 | 4 | 11 | 28 | |
| GSE46452 | KLK14 | 43847 | 45 | 1 | 13 | |
| GSE47630 | KLK14 | 43847 | 9 | 6 | 25 | |
| GSE54993 | KLK14 | 43847 | 17 | 4 | 49 | |
| GSE54994 | KLK14 | 43847 | 4 | 14 | 35 | |
| GSE60625 | KLK14 | 43847 | 9 | 0 | 2 | |
| GSE74703 | KLK14 | 43847 | 4 | 7 | 25 | |
| GSE74704 | KLK14 | 43847 | 3 | 1 | 16 | |
| TCGA | KLK14 | 43847 | 14 | 19 | 63 |
Total number of gains: 115; Total number of losses: 70; Total Number of normals: 303.
Somatic mutations of KLK14:
Generating mutation plots.
Highly correlated genes for KLK14:
Showing top 20/441 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLK14 | VGF | 0.790552 | 3 | 0 | 3 |
| KLK14 | CCDC106 | 0.778877 | 3 | 0 | 3 |
| KLK14 | FRS3 | 0.772967 | 3 | 0 | 3 |
| KLK14 | TM4SF5 | 0.760757 | 3 | 0 | 3 |
| KLK14 | ZIC1 | 0.754517 | 3 | 0 | 3 |
| KLK14 | SCN2A | 0.728197 | 3 | 0 | 3 |
| KLK14 | AGER | 0.72651 | 3 | 0 | 3 |
| KLK14 | PHOX2A | 0.720801 | 3 | 0 | 3 |
| KLK14 | ZP2 | 0.718223 | 3 | 0 | 3 |
| KLK14 | PSD | 0.71658 | 3 | 0 | 3 |
| KLK14 | PASD1 | 0.715187 | 3 | 0 | 3 |
| KLK14 | PRSS50 | 0.712431 | 3 | 0 | 3 |
| KLK14 | CHSY3 | 0.711242 | 3 | 0 | 3 |
| KLK14 | CITED1 | 0.709111 | 3 | 0 | 3 |
| KLK14 | HPCA | 0.707296 | 3 | 0 | 3 |
| KLK14 | GRM2 | 0.703267 | 4 | 0 | 4 |
| KLK14 | TFEB | 0.702944 | 3 | 0 | 3 |
| KLK14 | CHI3L2 | 0.69871 | 3 | 0 | 3 |
| KLK14 | CDC25C | 0.697338 | 3 | 0 | 3 |
| KLK14 | RHAG | 0.696905 | 4 | 0 | 3 |
For details and further investigation, click here
