| Full name: interferon alpha 1 | Alias Symbol: IFNA@|IFL|IFN|IFN-ALPHA|IFNA13|IFN-alphaD | ||
| Type: protein-coding gene | Cytoband: 9p21.3 | ||
| Entrez ID: 3439 | HGNC ID: HGNC:5417 | Ensembl Gene: ENSG00000197919 | OMIM ID: 147660 |
| Related drugs: DITIOCARB, IMIQUIMOD, RONTALIZUMAB... [more] | |||
Screen Evidence:
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IFNA1 involved pathways:
Expression of IFNA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFNA1 | 3439 | 208375_at | 0.0581 | 0.7452 | |
| GSE20347 | IFNA1 | 3439 | 208375_at | -0.0219 | 0.6890 | |
| GSE23400 | IFNA1 | 3439 | 208375_at | -0.0956 | 0.0001 | |
| GSE26886 | IFNA1 | 3439 | 208375_at | 0.0417 | 0.6633 | |
| GSE29001 | IFNA1 | 3439 | 208375_at | -0.1489 | 0.2060 | |
| GSE38129 | IFNA1 | 3439 | 208375_at | -0.0552 | 0.2377 | |
| GSE45670 | IFNA1 | 3439 | 208375_at | 0.1471 | 0.0068 | |
| GSE63941 | IFNA1 | 3439 | 208375_at | -0.0272 | 0.8639 | |
| GSE77861 | IFNA1 | 3439 | 208375_at | -0.0364 | 0.6783 | |
| TCGA | IFNA1 | 3439 | RNAseq | 0.7121 | 0.5493 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IFNA1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of IFNA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFNA1 | 3439 | 2 | 17 | 11 | |
| GSE20123 | IFNA1 | 3439 | 2 | 17 | 11 | |
| GSE43470 | IFNA1 | 3439 | 3 | 13 | 27 | |
| GSE46452 | IFNA1 | 3439 | 2 | 24 | 33 | |
| GSE47630 | IFNA1 | 3439 | 3 | 27 | 10 | |
| GSE54993 | IFNA1 | 3439 | 7 | 2 | 61 | |
| GSE54994 | IFNA1 | 3439 | 8 | 17 | 28 | |
| GSE60625 | IFNA1 | 3439 | 3 | 0 | 8 | |
| GSE74703 | IFNA1 | 3439 | 3 | 10 | 23 | |
| GSE74704 | IFNA1 | 3439 | 0 | 13 | 7 | |
| TCGA | IFNA1 | 3439 | 11 | 53 | 32 |
Total number of gains: 44; Total number of losses: 193; Total Number of normals: 251.
Somatic mutations of IFNA1:
Generating mutation plots.
Highly correlated genes for IFNA1:
Showing top 20/117 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFNA1 | IFNA16 | 0.65865 | 3 | 0 | 3 |
| IFNA1 | DPYSL4 | 0.646595 | 3 | 0 | 3 |
| IFNA1 | C8B | 0.644938 | 3 | 0 | 3 |
| IFNA1 | ART1 | 0.64328 | 3 | 0 | 3 |
| IFNA1 | ATP2B3 | 0.642043 | 4 | 0 | 3 |
| IFNA1 | TUBB4A | 0.638852 | 3 | 0 | 3 |
| IFNA1 | LTK | 0.638104 | 3 | 0 | 3 |
| IFNA1 | DDN | 0.637167 | 4 | 0 | 3 |
| IFNA1 | GBX2 | 0.620931 | 3 | 0 | 3 |
| IFNA1 | MCHR1 | 0.620899 | 3 | 0 | 3 |
| IFNA1 | OVGP1 | 0.618973 | 4 | 0 | 3 |
| IFNA1 | CRHR2 | 0.617245 | 3 | 0 | 3 |
| IFNA1 | NR1H4 | 0.612691 | 3 | 0 | 3 |
| IFNA1 | RRS1-AS1 | 0.610162 | 3 | 0 | 3 |
| IFNA1 | GRK6 | 0.609214 | 4 | 0 | 4 |
| IFNA1 | GPR31 | 0.604022 | 3 | 0 | 3 |
| IFNA1 | GRIP2 | 0.600846 | 3 | 0 | 3 |
| IFNA1 | TRIM10 | 0.599355 | 3 | 0 | 3 |
| IFNA1 | E2F4 | 0.598229 | 3 | 0 | 3 |
| IFNA1 | C8A | 0.589942 | 4 | 0 | 3 |
For details and further investigation, click here
