| Full name: protein phosphatase 2 regulatory subunit B'beta | Alias Symbol: FLJ35411|B56B|PR61B|B56beta | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 5526 | HGNC ID: HGNC:9310 | Ensembl Gene: ENSG00000068971 | OMIM ID: 601644 |
| Drug and gene relationship at DGIdb | |||
PPP2R5B involved pathways:
Expression of PPP2R5B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP2R5B | 5526 | 204611_s_at | 0.2979 | 0.4242 | |
| GSE20347 | PPP2R5B | 5526 | 204611_s_at | 0.2286 | 0.0169 | |
| GSE23400 | PPP2R5B | 5526 | 204611_s_at | 0.1246 | 0.0036 | |
| GSE26886 | PPP2R5B | 5526 | 204611_s_at | 0.8484 | 0.0000 | |
| GSE29001 | PPP2R5B | 5526 | 204611_s_at | 0.0152 | 0.9617 | |
| GSE38129 | PPP2R5B | 5526 | 204611_s_at | 0.0298 | 0.8122 | |
| GSE45670 | PPP2R5B | 5526 | 204611_s_at | 0.4000 | 0.0012 | |
| GSE53622 | PPP2R5B | 5526 | 16722 | 0.5534 | 0.0000 | |
| GSE53624 | PPP2R5B | 5526 | 109090 | 0.6199 | 0.0000 | |
| GSE63941 | PPP2R5B | 5526 | 204611_s_at | 0.0071 | 0.9862 | |
| GSE77861 | PPP2R5B | 5526 | 204611_s_at | 0.3369 | 0.0518 | |
| GSE97050 | PPP2R5B | 5526 | A_33_P3318237 | 0.3333 | 0.2152 | |
| SRP007169 | PPP2R5B | 5526 | RNAseq | 1.9657 | 0.0079 | |
| SRP008496 | PPP2R5B | 5526 | RNAseq | 1.2487 | 0.0112 | |
| SRP064894 | PPP2R5B | 5526 | RNAseq | 0.6136 | 0.0000 | |
| SRP133303 | PPP2R5B | 5526 | RNAseq | 0.6642 | 0.0022 | |
| SRP159526 | PPP2R5B | 5526 | RNAseq | 0.5696 | 0.0024 | |
| SRP193095 | PPP2R5B | 5526 | RNAseq | 1.0240 | 0.0000 | |
| SRP219564 | PPP2R5B | 5526 | RNAseq | -0.0727 | 0.8698 | |
| TCGA | PPP2R5B | 5526 | RNAseq | -0.0750 | 0.2892 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by PPP2R5B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPP2R5B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP2R5B | 5526 | 7 | 6 | 17 | |
| GSE20123 | PPP2R5B | 5526 | 7 | 6 | 17 | |
| GSE43470 | PPP2R5B | 5526 | 1 | 3 | 39 | |
| GSE46452 | PPP2R5B | 5526 | 10 | 4 | 45 | |
| GSE47630 | PPP2R5B | 5526 | 5 | 6 | 29 | |
| GSE54993 | PPP2R5B | 5526 | 3 | 0 | 67 | |
| GSE54994 | PPP2R5B | 5526 | 6 | 5 | 42 | |
| GSE60625 | PPP2R5B | 5526 | 0 | 3 | 8 | |
| GSE74703 | PPP2R5B | 5526 | 1 | 1 | 34 | |
| GSE74704 | PPP2R5B | 5526 | 5 | 4 | 11 | |
| TCGA | PPP2R5B | 5526 | 23 | 7 | 66 |
Total number of gains: 68; Total number of losses: 45; Total Number of normals: 375.
Somatic mutations of PPP2R5B:
Generating mutation plots.
Highly correlated genes for PPP2R5B:
Showing top 20/892 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP2R5B | RILPL1 | 0.774429 | 3 | 0 | 3 |
| PPP2R5B | GPRC5C | 0.723427 | 3 | 0 | 3 |
| PPP2R5B | RHBDF2 | 0.716022 | 4 | 0 | 4 |
| PPP2R5B | SMG6 | 0.714808 | 3 | 0 | 3 |
| PPP2R5B | TGFB1I1 | 0.712639 | 3 | 0 | 3 |
| PPP2R5B | TRAF7 | 0.70758 | 3 | 0 | 3 |
| PPP2R5B | FZR1 | 0.702037 | 3 | 0 | 3 |
| PPP2R5B | FRS3 | 0.70182 | 3 | 0 | 3 |
| PPP2R5B | NGF | 0.696905 | 5 | 0 | 4 |
| PPP2R5B | INO80B | 0.69442 | 4 | 0 | 3 |
| PPP2R5B | POLD1 | 0.686628 | 3 | 0 | 3 |
| PPP2R5B | AGAP2-AS1 | 0.682681 | 4 | 0 | 4 |
| PPP2R5B | TSPYL2 | 0.682222 | 5 | 0 | 3 |
| PPP2R5B | B3GNT9 | 0.679819 | 6 | 0 | 5 |
| PPP2R5B | SPEF1 | 0.679585 | 3 | 0 | 3 |
| PPP2R5B | CABP4 | 0.672907 | 3 | 0 | 3 |
| PPP2R5B | FABP2 | 0.662569 | 3 | 0 | 3 |
| PPP2R5B | STC2 | 0.659134 | 7 | 0 | 5 |
| PPP2R5B | MRPL14 | 0.656522 | 3 | 0 | 3 |
| PPP2R5B | RAB1B | 0.656516 | 3 | 0 | 3 |
For details and further investigation, click here
