| Full name: DEAD-box helicase 56 | Alias Symbol: NOH61 | ||
| Type: protein-coding gene | Cytoband: 7p13 | ||
| Entrez ID: 54606 | HGNC ID: HGNC:18193 | Ensembl Gene: ENSG00000136271 | OMIM ID: 608023 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DDX56:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DDX56 | 54606 | 217754_at | 0.6877 | 0.0934 | |
| GSE20347 | DDX56 | 54606 | 217754_at | 0.4623 | 0.0006 | |
| GSE23400 | DDX56 | 54606 | 217754_at | 0.4700 | 0.0000 | |
| GSE26886 | DDX56 | 54606 | 217754_at | 0.8634 | 0.0000 | |
| GSE29001 | DDX56 | 54606 | 217754_at | 0.3750 | 0.0211 | |
| GSE38129 | DDX56 | 54606 | 217754_at | 0.6479 | 0.0000 | |
| GSE45670 | DDX56 | 54606 | 217754_at | 0.4524 | 0.0006 | |
| GSE53622 | DDX56 | 54606 | 7547 | 0.5627 | 0.0000 | |
| GSE53624 | DDX56 | 54606 | 7814 | 0.7819 | 0.0000 | |
| GSE63941 | DDX56 | 54606 | 217754_at | 1.4007 | 0.0020 | |
| GSE77861 | DDX56 | 54606 | 217754_at | 0.3614 | 0.0652 | |
| GSE97050 | DDX56 | 54606 | A_33_P3372844 | 0.3643 | 0.2684 | |
| SRP007169 | DDX56 | 54606 | RNAseq | 0.8470 | 0.0833 | |
| SRP008496 | DDX56 | 54606 | RNAseq | 1.1606 | 0.0042 | |
| SRP064894 | DDX56 | 54606 | RNAseq | 0.5617 | 0.0017 | |
| SRP133303 | DDX56 | 54606 | RNAseq | 0.3446 | 0.0278 | |
| SRP159526 | DDX56 | 54606 | RNAseq | 0.4055 | 0.1266 | |
| SRP193095 | DDX56 | 54606 | RNAseq | 0.4013 | 0.0003 | |
| SRP219564 | DDX56 | 54606 | RNAseq | 0.2274 | 0.4066 | |
| TCGA | DDX56 | 54606 | RNAseq | 0.1545 | 0.0031 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by DDX56 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DDX56:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DDX56 | 54606 | 13 | 0 | 17 | |
| GSE20123 | DDX56 | 54606 | 13 | 0 | 17 | |
| GSE43470 | DDX56 | 54606 | 4 | 0 | 39 | |
| GSE46452 | DDX56 | 54606 | 11 | 1 | 47 | |
| GSE47630 | DDX56 | 54606 | 8 | 1 | 31 | |
| GSE54993 | DDX56 | 54606 | 0 | 8 | 62 | |
| GSE54994 | DDX56 | 54606 | 16 | 3 | 34 | |
| GSE60625 | DDX56 | 54606 | 0 | 0 | 11 | |
| GSE74703 | DDX56 | 54606 | 4 | 0 | 32 | |
| GSE74704 | DDX56 | 54606 | 7 | 0 | 13 | |
| TCGA | DDX56 | 54606 | 50 | 7 | 39 |
Total number of gains: 126; Total number of losses: 20; Total Number of normals: 342.
Somatic mutations of DDX56:
Generating mutation plots.
Highly correlated genes for DDX56:
Showing top 20/1924 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DDX56 | PMS2 | 0.787504 | 3 | 0 | 3 |
| DDX56 | SLC39A3 | 0.786603 | 3 | 0 | 3 |
| DDX56 | EBNA1BP2 | 0.773834 | 3 | 0 | 3 |
| DDX56 | SNX27 | 0.772175 | 3 | 0 | 3 |
| DDX56 | NEK3 | 0.766063 | 3 | 0 | 3 |
| DDX56 | GTF2H3 | 0.764563 | 3 | 0 | 3 |
| DDX56 | SCNM1 | 0.751281 | 3 | 0 | 3 |
| DDX56 | ZNF32 | 0.750443 | 3 | 0 | 3 |
| DDX56 | TOP1MT | 0.749869 | 7 | 0 | 7 |
| DDX56 | EIF2AK1 | 0.746559 | 10 | 0 | 10 |
| DDX56 | RILPL1 | 0.741818 | 3 | 0 | 3 |
| DDX56 | ELP2 | 0.740015 | 3 | 0 | 3 |
| DDX56 | KRTCAP2 | 0.737358 | 5 | 0 | 4 |
| DDX56 | ZNF707 | 0.736776 | 3 | 0 | 3 |
| DDX56 | YWHAG | 0.736535 | 5 | 0 | 5 |
| DDX56 | DDX39A | 0.735702 | 12 | 0 | 12 |
| DDX56 | MRPS5 | 0.735186 | 4 | 0 | 3 |
| DDX56 | FKBP2 | 0.731633 | 3 | 0 | 3 |
| DDX56 | KLHL13 | 0.730717 | 3 | 0 | 3 |
| DDX56 | CAD | 0.729659 | 12 | 0 | 12 |
For details and further investigation, click here
