| Full name: elongator acetyltransferase complex subunit 2 | Alias Symbol: FLJ10879|StIP | ||
| Type: protein-coding gene | Cytoband: 18q12.2 | ||
| Entrez ID: 55250 | HGNC ID: HGNC:18248 | Ensembl Gene: ENSG00000134759 | OMIM ID: 616054 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ELP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ELP2 | 55250 | 231713_s_at | 0.2459 | 0.4646 | |
| GSE26886 | ELP2 | 55250 | 231713_s_at | 0.3845 | 0.0564 | |
| GSE45670 | ELP2 | 55250 | 231713_s_at | 0.0858 | 0.5999 | |
| GSE53622 | ELP2 | 55250 | 129 | -0.0485 | 0.4317 | |
| GSE53624 | ELP2 | 55250 | 129 | 0.3467 | 0.0000 | |
| GSE63941 | ELP2 | 55250 | 231713_s_at | -0.3637 | 0.5146 | |
| GSE77861 | ELP2 | 55250 | 231713_s_at | 0.1967 | 0.3031 | |
| GSE97050 | ELP2 | 55250 | A_23_P78438 | -0.1436 | 0.4603 | |
| SRP007169 | ELP2 | 55250 | RNAseq | 0.4179 | 0.2310 | |
| SRP008496 | ELP2 | 55250 | RNAseq | 0.6579 | 0.0373 | |
| SRP064894 | ELP2 | 55250 | RNAseq | 0.2349 | 0.0265 | |
| SRP133303 | ELP2 | 55250 | RNAseq | 0.1384 | 0.2347 | |
| SRP159526 | ELP2 | 55250 | RNAseq | 0.0802 | 0.7356 | |
| SRP193095 | ELP2 | 55250 | RNAseq | 0.1827 | 0.0547 | |
| SRP219564 | ELP2 | 55250 | RNAseq | 0.0570 | 0.8370 | |
| TCGA | ELP2 | 55250 | RNAseq | -0.0447 | 0.4568 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ELP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ELP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELP2 | 55250 | 2 | 5 | 23 | |
| GSE20123 | ELP2 | 55250 | 2 | 5 | 23 | |
| GSE43470 | ELP2 | 55250 | 0 | 3 | 40 | |
| GSE46452 | ELP2 | 55250 | 1 | 25 | 33 | |
| GSE47630 | ELP2 | 55250 | 5 | 20 | 15 | |
| GSE54993 | ELP2 | 55250 | 8 | 1 | 61 | |
| GSE54994 | ELP2 | 55250 | 1 | 16 | 36 | |
| GSE60625 | ELP2 | 55250 | 0 | 4 | 7 | |
| GSE74703 | ELP2 | 55250 | 0 | 3 | 33 | |
| GSE74704 | ELP2 | 55250 | 1 | 4 | 15 | |
| TCGA | ELP2 | 55250 | 16 | 40 | 40 |
Total number of gains: 36; Total number of losses: 126; Total Number of normals: 326.
Somatic mutations of ELP2:
Generating mutation plots.
Highly correlated genes for ELP2:
Showing top 20/262 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELP2 | ZMYM3 | 0.810293 | 3 | 0 | 3 |
| ELP2 | RCN1 | 0.771969 | 3 | 0 | 3 |
| ELP2 | MRPL9 | 0.762098 | 3 | 0 | 3 |
| ELP2 | DDX56 | 0.740015 | 3 | 0 | 3 |
| ELP2 | CHST3 | 0.739664 | 3 | 0 | 3 |
| ELP2 | CUL7 | 0.735222 | 3 | 0 | 3 |
| ELP2 | TNS3 | 0.731933 | 3 | 0 | 3 |
| ELP2 | NEK6 | 0.731686 | 3 | 0 | 3 |
| ELP2 | SCMH1 | 0.729787 | 3 | 0 | 3 |
| ELP2 | GZF1 | 0.728594 | 3 | 0 | 3 |
| ELP2 | COG2 | 0.727753 | 3 | 0 | 3 |
| ELP2 | THAP11 | 0.72567 | 3 | 0 | 3 |
| ELP2 | CRLS1 | 0.722311 | 4 | 0 | 4 |
| ELP2 | OAF | 0.720552 | 3 | 0 | 3 |
| ELP2 | PLCB2 | 0.718144 | 3 | 0 | 3 |
| ELP2 | THOC5 | 0.717738 | 3 | 0 | 3 |
| ELP2 | TBCC | 0.709499 | 3 | 0 | 3 |
| ELP2 | EEFSEC | 0.703216 | 3 | 0 | 3 |
| ELP2 | TTC4 | 0.697729 | 3 | 0 | 3 |
| ELP2 | ZNF419 | 0.697023 | 3 | 0 | 3 |
For details and further investigation, click here
