| Full name: sorting nexin 27 | Alias Symbol: MY014|KIAA0488|MGC20471 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 81609 | HGNC ID: HGNC:20073 | Ensembl Gene: ENSG00000143376 | OMIM ID: 611541 |
| Drug and gene relationship at DGIdb | |||
Expression of SNX27:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNX27 | 81609 | 221006_s_at | -0.1459 | 0.8488 | |
| GSE20347 | SNX27 | 81609 | 221006_s_at | 0.2702 | 0.0344 | |
| GSE23400 | SNX27 | 81609 | 221006_s_at | -0.1069 | 0.1068 | |
| GSE26886 | SNX27 | 81609 | 221498_at | 0.8447 | 0.0000 | |
| GSE29001 | SNX27 | 81609 | 221498_at | 0.5622 | 0.0215 | |
| GSE38129 | SNX27 | 81609 | 221006_s_at | -0.0047 | 0.9888 | |
| GSE45670 | SNX27 | 81609 | 221498_at | 0.0643 | 0.7256 | |
| GSE53622 | SNX27 | 81609 | 48005 | 0.3347 | 0.0000 | |
| GSE53624 | SNX27 | 81609 | 48005 | 0.5005 | 0.0000 | |
| GSE63941 | SNX27 | 81609 | 221498_at | 0.0691 | 0.8676 | |
| GSE77861 | SNX27 | 81609 | 221006_s_at | 0.3615 | 0.1526 | |
| GSE97050 | SNX27 | 81609 | A_23_P201238 | -0.0374 | 0.9350 | |
| SRP007169 | SNX27 | 81609 | RNAseq | 1.0756 | 0.0007 | |
| SRP008496 | SNX27 | 81609 | RNAseq | 1.0243 | 0.0000 | |
| SRP064894 | SNX27 | 81609 | RNAseq | 0.2404 | 0.1198 | |
| SRP133303 | SNX27 | 81609 | RNAseq | 0.3302 | 0.0165 | |
| SRP159526 | SNX27 | 81609 | RNAseq | 0.6242 | 0.0172 | |
| SRP193095 | SNX27 | 81609 | RNAseq | 0.4058 | 0.0000 | |
| SRP219564 | SNX27 | 81609 | RNAseq | -0.0196 | 0.9535 | |
| TCGA | SNX27 | 81609 | RNAseq | -0.0330 | 0.4872 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SNX27 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNX27:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNX27 | 81609 | 15 | 0 | 15 | |
| GSE20123 | SNX27 | 81609 | 15 | 0 | 15 | |
| GSE43470 | SNX27 | 81609 | 8 | 2 | 33 | |
| GSE46452 | SNX27 | 81609 | 2 | 1 | 56 | |
| GSE47630 | SNX27 | 81609 | 14 | 0 | 26 | |
| GSE54993 | SNX27 | 81609 | 0 | 4 | 66 | |
| GSE54994 | SNX27 | 81609 | 15 | 0 | 38 | |
| GSE60625 | SNX27 | 81609 | 0 | 0 | 11 | |
| GSE74703 | SNX27 | 81609 | 7 | 1 | 28 | |
| GSE74704 | SNX27 | 81609 | 7 | 0 | 13 | |
| TCGA | SNX27 | 81609 | 38 | 2 | 56 |
Total number of gains: 121; Total number of losses: 10; Total Number of normals: 357.
Somatic mutations of SNX27:
Generating mutation plots.
Highly correlated genes for SNX27:
Showing top 20/814 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNX27 | ZNF704 | 0.810228 | 3 | 0 | 3 |
| SNX27 | DDX56 | 0.772175 | 3 | 0 | 3 |
| SNX27 | GAS6 | 0.754297 | 3 | 0 | 3 |
| SNX27 | RAD21 | 0.75183 | 3 | 0 | 3 |
| SNX27 | FAM53C | 0.7451 | 3 | 0 | 3 |
| SNX27 | WDR81 | 0.730955 | 4 | 0 | 4 |
| SNX27 | LIX1L | 0.728473 | 3 | 0 | 3 |
| SNX27 | DHRSX | 0.726892 | 3 | 0 | 3 |
| SNX27 | MCL1 | 0.72606 | 3 | 0 | 3 |
| SNX27 | PIK3R1 | 0.714841 | 3 | 0 | 3 |
| SNX27 | TTC7B | 0.711023 | 6 | 0 | 5 |
| SNX27 | SENP6 | 0.710919 | 3 | 0 | 3 |
| SNX27 | CTBP2 | 0.708195 | 4 | 0 | 4 |
| SNX27 | GNG10 | 0.707524 | 3 | 0 | 3 |
| SNX27 | ZBED1 | 0.706888 | 3 | 0 | 3 |
| SNX27 | ZNF627 | 0.706159 | 3 | 0 | 3 |
| SNX27 | TMEM205 | 0.703398 | 3 | 0 | 3 |
| SNX27 | POLR1B | 0.702835 | 5 | 0 | 4 |
| SNX27 | BSN | 0.701157 | 3 | 0 | 3 |
| SNX27 | FRMD3 | 0.700923 | 3 | 0 | 3 |
For details and further investigation, click here
