| Full name: mitochondrial ribosomal protein S5 | Alias Symbol: MRP-S5|S5mt | ||
| Type: protein-coding gene | Cytoband: 2q11.1 | ||
| Entrez ID: 64969 | HGNC ID: HGNC:14498 | Ensembl Gene: ENSG00000144029 | OMIM ID: 611972 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MRPS5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPS5 | 64969 | 224333_s_at | 0.3959 | 0.1684 | |
| GSE26886 | MRPS5 | 64969 | 224333_s_at | 0.0359 | 0.8752 | |
| GSE45670 | MRPS5 | 64969 | 224333_s_at | 0.2768 | 0.1111 | |
| GSE53622 | MRPS5 | 64969 | 2874 | 0.1197 | 0.3672 | |
| GSE53624 | MRPS5 | 64969 | 2874 | 0.1922 | 0.0008 | |
| GSE63941 | MRPS5 | 64969 | 224333_s_at | 0.4614 | 0.1980 | |
| GSE77861 | MRPS5 | 64969 | 224333_s_at | 0.3556 | 0.0340 | |
| GSE97050 | MRPS5 | 64969 | A_23_P28538 | 0.0900 | 0.7579 | |
| SRP007169 | MRPS5 | 64969 | RNAseq | -0.0129 | 0.9676 | |
| SRP008496 | MRPS5 | 64969 | RNAseq | -0.1829 | 0.3999 | |
| SRP064894 | MRPS5 | 64969 | RNAseq | 0.4074 | 0.0382 | |
| SRP133303 | MRPS5 | 64969 | RNAseq | 0.2218 | 0.0553 | |
| SRP159526 | MRPS5 | 64969 | RNAseq | 0.2312 | 0.3371 | |
| SRP193095 | MRPS5 | 64969 | RNAseq | -0.0359 | 0.7379 | |
| SRP219564 | MRPS5 | 64969 | RNAseq | 0.0200 | 0.9507 | |
| TCGA | MRPS5 | 64969 | RNAseq | 0.0828 | 0.1123 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPS5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPS5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPS5 | 64969 | 8 | 1 | 21 | |
| GSE20123 | MRPS5 | 64969 | 8 | 1 | 21 | |
| GSE43470 | MRPS5 | 64969 | 3 | 2 | 38 | |
| GSE46452 | MRPS5 | 64969 | 2 | 3 | 54 | |
| GSE47630 | MRPS5 | 64969 | 7 | 0 | 33 | |
| GSE54993 | MRPS5 | 64969 | 0 | 6 | 64 | |
| GSE54994 | MRPS5 | 64969 | 11 | 0 | 42 | |
| GSE60625 | MRPS5 | 64969 | 0 | 3 | 8 | |
| GSE74703 | MRPS5 | 64969 | 3 | 1 | 32 | |
| GSE74704 | MRPS5 | 64969 | 5 | 0 | 15 | |
| TCGA | MRPS5 | 64969 | 35 | 4 | 57 |
Total number of gains: 82; Total number of losses: 21; Total Number of normals: 385.
Somatic mutations of MRPS5:
Generating mutation plots.
Highly correlated genes for MRPS5:
Showing top 20/855 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPS5 | THOC1 | 0.812964 | 3 | 0 | 3 |
| MRPS5 | CD3EAP | 0.80796 | 3 | 0 | 3 |
| MRPS5 | TMEM135 | 0.80038 | 3 | 0 | 3 |
| MRPS5 | TXNRD1 | 0.793906 | 3 | 0 | 3 |
| MRPS5 | NSMAF | 0.791359 | 3 | 0 | 3 |
| MRPS5 | MOB3C | 0.782636 | 3 | 0 | 3 |
| MRPS5 | UAP1L1 | 0.779613 | 3 | 0 | 3 |
| MRPS5 | U2SURP | 0.778804 | 4 | 0 | 4 |
| MRPS5 | USP14 | 0.776439 | 3 | 0 | 3 |
| MRPS5 | NOL10 | 0.769266 | 4 | 0 | 3 |
| MRPS5 | GPR153 | 0.768958 | 3 | 0 | 3 |
| MRPS5 | DDX27 | 0.766873 | 4 | 0 | 4 |
| MRPS5 | PXN | 0.765876 | 3 | 0 | 3 |
| MRPS5 | ITPR3 | 0.760412 | 3 | 0 | 3 |
| MRPS5 | KLHL13 | 0.758666 | 3 | 0 | 3 |
| MRPS5 | GPATCH2 | 0.746794 | 3 | 0 | 3 |
| MRPS5 | BTG3 | 0.743577 | 3 | 0 | 3 |
| MRPS5 | MNAT1 | 0.741694 | 4 | 0 | 3 |
| MRPS5 | MSTO1 | 0.741412 | 3 | 0 | 3 |
| MRPS5 | KTN1 | 0.739918 | 3 | 0 | 3 |
For details and further investigation, click here
