| Full name: inverted formin, FH2 and WH2 domain containing | Alias Symbol: MGC13251 | ||
| Type: protein-coding gene | Cytoband: 14q32.33 | ||
| Entrez ID: 64423 | HGNC ID: HGNC:23791 | Ensembl Gene: ENSG00000203485 | OMIM ID: 610982 |
| Drug and gene relationship at DGIdb | |||
Expression of INF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | INF2 | 64423 | 218144_s_at | 0.2357 | 0.4736 | |
| GSE20347 | INF2 | 64423 | 218144_s_at | 0.0487 | 0.6607 | |
| GSE23400 | INF2 | 64423 | 218144_s_at | -0.0479 | 0.4039 | |
| GSE26886 | INF2 | 64423 | 218144_s_at | 0.2662 | 0.0275 | |
| GSE29001 | INF2 | 64423 | 218144_s_at | 0.1964 | 0.5213 | |
| GSE38129 | INF2 | 64423 | 218144_s_at | 0.0347 | 0.7399 | |
| GSE45670 | INF2 | 64423 | 218144_s_at | 0.1236 | 0.2614 | |
| GSE53622 | INF2 | 64423 | 75297 | 0.4641 | 0.0000 | |
| GSE53624 | INF2 | 64423 | 26743 | -1.1992 | 0.0000 | |
| GSE63941 | INF2 | 64423 | 218144_s_at | 0.2342 | 0.3100 | |
| GSE77861 | INF2 | 64423 | 218144_s_at | 0.0101 | 0.9688 | |
| GSE97050 | INF2 | 64423 | A_23_P394836 | -1.3309 | 0.1189 | |
| SRP007169 | INF2 | 64423 | RNAseq | 0.3453 | 0.4911 | |
| SRP008496 | INF2 | 64423 | RNAseq | 0.1302 | 0.6591 | |
| SRP064894 | INF2 | 64423 | RNAseq | 0.6513 | 0.0000 | |
| SRP133303 | INF2 | 64423 | RNAseq | 0.2808 | 0.0095 | |
| SRP159526 | INF2 | 64423 | RNAseq | 0.6044 | 0.0626 | |
| SRP193095 | INF2 | 64423 | RNAseq | 0.3350 | 0.0918 | |
| SRP219564 | INF2 | 64423 | RNAseq | 0.6077 | 0.0936 | |
| TCGA | INF2 | 64423 | RNAseq | -0.1095 | 0.0737 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by INF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of INF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | INF2 | 64423 | 11 | 3 | 16 | |
| GSE20123 | INF2 | 64423 | 10 | 2 | 18 | |
| GSE43470 | INF2 | 64423 | 6 | 4 | 33 | |
| GSE46452 | INF2 | 64423 | 19 | 4 | 36 | |
| GSE47630 | INF2 | 64423 | 10 | 8 | 22 | |
| GSE54993 | INF2 | 64423 | 4 | 10 | 56 | |
| GSE54994 | INF2 | 64423 | 20 | 4 | 29 | |
| GSE60625 | INF2 | 64423 | 0 | 2 | 9 | |
| GSE74703 | INF2 | 64423 | 5 | 3 | 28 | |
| GSE74704 | INF2 | 64423 | 5 | 2 | 13 | |
| TCGA | INF2 | 64423 | 32 | 18 | 46 |
Total number of gains: 122; Total number of losses: 60; Total Number of normals: 306.
Somatic mutations of INF2:
Generating mutation plots.
Highly correlated genes for INF2:
Showing top 20/200 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| INF2 | EYS | 0.796367 | 3 | 0 | 3 |
| INF2 | NKAIN4 | 0.766035 | 3 | 0 | 3 |
| INF2 | DFFB | 0.734623 | 3 | 0 | 3 |
| INF2 | ISLR2 | 0.723815 | 3 | 0 | 3 |
| INF2 | CNTN6 | 0.721564 | 3 | 0 | 3 |
| INF2 | MEGF8 | 0.711004 | 3 | 0 | 3 |
| INF2 | SHISA8 | 0.709919 | 3 | 0 | 3 |
| INF2 | CDH23 | 0.706513 | 3 | 0 | 3 |
| INF2 | PEX11G | 0.705793 | 3 | 0 | 3 |
| INF2 | RGP1 | 0.699206 | 3 | 0 | 3 |
| INF2 | JSRP1 | 0.698881 | 3 | 0 | 3 |
| INF2 | HMGB4 | 0.694861 | 3 | 0 | 3 |
| INF2 | CDH4 | 0.680239 | 4 | 0 | 3 |
| INF2 | CD70 | 0.680165 | 5 | 0 | 5 |
| INF2 | KRTAP4-1 | 0.673895 | 4 | 0 | 3 |
| INF2 | REM2 | 0.672188 | 3 | 0 | 3 |
| INF2 | TNFRSF25 | 0.670731 | 5 | 0 | 5 |
| INF2 | FBXO15 | 0.670566 | 3 | 0 | 3 |
| INF2 | ZFPM1 | 0.670063 | 3 | 0 | 3 |
| INF2 | GRIN1 | 0.668344 | 4 | 0 | 3 |
For details and further investigation, click here
