| Full name: DExH-box helicase 29 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q11.2 | ||
| Entrez ID: 54505 | HGNC ID: HGNC:15815 | Ensembl Gene: ENSG00000067248 | OMIM ID: 612720 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DHX29:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DHX29 | 54505 | 212648_at | -0.4712 | 0.3912 | |
| GSE20347 | DHX29 | 54505 | 212648_at | -0.7739 | 0.0000 | |
| GSE23400 | DHX29 | 54505 | 212648_at | -0.2606 | 0.0057 | |
| GSE26886 | DHX29 | 54505 | 212648_at | -0.8183 | 0.0026 | |
| GSE29001 | DHX29 | 54505 | 212648_at | -0.4541 | 0.0386 | |
| GSE38129 | DHX29 | 54505 | 212648_at | -0.4977 | 0.0003 | |
| GSE45670 | DHX29 | 54505 | 212648_at | -0.3079 | 0.0336 | |
| GSE53622 | DHX29 | 54505 | 102219 | -0.6119 | 0.0000 | |
| GSE53624 | DHX29 | 54505 | 102219 | -0.4662 | 0.0000 | |
| GSE63941 | DHX29 | 54505 | 212648_at | -1.5488 | 0.0032 | |
| GSE77861 | DHX29 | 54505 | 212648_at | -0.5490 | 0.0822 | |
| GSE97050 | DHX29 | 54505 | A_23_P81463 | -0.0738 | 0.7144 | |
| SRP007169 | DHX29 | 54505 | RNAseq | -1.3266 | 0.0001 | |
| SRP008496 | DHX29 | 54505 | RNAseq | -1.2763 | 0.0000 | |
| SRP064894 | DHX29 | 54505 | RNAseq | -0.6929 | 0.0000 | |
| SRP133303 | DHX29 | 54505 | RNAseq | -0.2187 | 0.1222 | |
| SRP159526 | DHX29 | 54505 | RNAseq | -0.2008 | 0.5905 | |
| SRP193095 | DHX29 | 54505 | RNAseq | -0.4543 | 0.0001 | |
| SRP219564 | DHX29 | 54505 | RNAseq | -0.4213 | 0.0924 | |
| TCGA | DHX29 | 54505 | RNAseq | -0.0969 | 0.0447 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by DHX29 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DHX29:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DHX29 | 54505 | 1 | 13 | 16 | |
| GSE20123 | DHX29 | 54505 | 1 | 13 | 16 | |
| GSE43470 | DHX29 | 54505 | 1 | 12 | 30 | |
| GSE46452 | DHX29 | 54505 | 1 | 27 | 31 | |
| GSE47630 | DHX29 | 54505 | 2 | 16 | 22 | |
| GSE54993 | DHX29 | 54505 | 8 | 1 | 61 | |
| GSE54994 | DHX29 | 54505 | 3 | 20 | 30 | |
| GSE60625 | DHX29 | 54505 | 0 | 0 | 11 | |
| GSE74703 | DHX29 | 54505 | 1 | 9 | 26 | |
| GSE74704 | DHX29 | 54505 | 1 | 6 | 13 | |
| TCGA | DHX29 | 54505 | 8 | 46 | 42 |
Total number of gains: 27; Total number of losses: 163; Total Number of normals: 298.
Somatic mutations of DHX29:
Generating mutation plots.
Highly correlated genes for DHX29:
Showing top 20/1211 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DHX29 | ATG2B | 0.785528 | 4 | 0 | 4 |
| DHX29 | DPY19L3 | 0.776994 | 3 | 0 | 3 |
| DHX29 | ZNF585A | 0.770463 | 3 | 0 | 3 |
| DHX29 | IMPACT | 0.764583 | 3 | 0 | 3 |
| DHX29 | ANGPTL4 | 0.753661 | 3 | 0 | 3 |
| DHX29 | PTCD2 | 0.75341 | 4 | 0 | 4 |
| DHX29 | KDM5D | 0.75254 | 3 | 0 | 3 |
| DHX29 | C11orf54 | 0.750156 | 4 | 0 | 4 |
| DHX29 | RNF135 | 0.743238 | 4 | 0 | 4 |
| DHX29 | SYNRG | 0.741553 | 3 | 0 | 3 |
| DHX29 | MRPS36 | 0.740507 | 7 | 0 | 7 |
| DHX29 | CCNYL1 | 0.735293 | 5 | 0 | 5 |
| DHX29 | FNIP1 | 0.731759 | 4 | 0 | 3 |
| DHX29 | SLC25A43 | 0.727964 | 5 | 0 | 5 |
| DHX29 | IPMK | 0.727461 | 4 | 0 | 4 |
| DHX29 | CHRNB1 | 0.722153 | 3 | 0 | 3 |
| DHX29 | SNX18 | 0.718716 | 4 | 0 | 4 |
| DHX29 | FAM174A | 0.718465 | 9 | 0 | 9 |
| DHX29 | ZCCHC9 | 0.715973 | 6 | 0 | 5 |
| DHX29 | APC | 0.712393 | 9 | 0 | 8 |
For details and further investigation, click here
