| Full name: ring finger protein 135 | Alias Symbol: MGC13061 | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 84282 | HGNC ID: HGNC:21158 | Ensembl Gene: ENSG00000181481 | OMIM ID: 611358 |
| Drug and gene relationship at DGIdb | |||
Expression of RNF135:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF135 | 84282 | 223592_s_at | -0.4498 | 0.2651 | |
| GSE26886 | RNF135 | 84282 | 223592_s_at | 0.2373 | 0.4132 | |
| GSE45670 | RNF135 | 84282 | 223592_s_at | -0.5149 | 0.0027 | |
| GSE53622 | RNF135 | 84282 | 4103 | -0.5573 | 0.0000 | |
| GSE53624 | RNF135 | 84282 | 4103 | -0.5742 | 0.0000 | |
| GSE63941 | RNF135 | 84282 | 223592_s_at | -0.0588 | 0.9143 | |
| GSE77861 | RNF135 | 84282 | 223592_s_at | -0.4988 | 0.1915 | |
| GSE97050 | RNF135 | 84282 | A_23_P252283 | -0.2463 | 0.3069 | |
| SRP007169 | RNF135 | 84282 | RNAseq | -1.7719 | 0.0000 | |
| SRP008496 | RNF135 | 84282 | RNAseq | -1.3606 | 0.0000 | |
| SRP064894 | RNF135 | 84282 | RNAseq | -0.1455 | 0.3464 | |
| SRP133303 | RNF135 | 84282 | RNAseq | -0.2879 | 0.0196 | |
| SRP159526 | RNF135 | 84282 | RNAseq | -0.4840 | 0.0603 | |
| SRP193095 | RNF135 | 84282 | RNAseq | -0.4415 | 0.0000 | |
| SRP219564 | RNF135 | 84282 | RNAseq | -0.4182 | 0.1574 | |
| TCGA | RNF135 | 84282 | RNAseq | 0.0628 | 0.3302 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by RNF135 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF135:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF135 | 84282 | 8 | 2 | 20 | |
| GSE20123 | RNF135 | 84282 | 9 | 2 | 19 | |
| GSE43470 | RNF135 | 84282 | 0 | 1 | 42 | |
| GSE46452 | RNF135 | 84282 | 33 | 1 | 25 | |
| GSE47630 | RNF135 | 84282 | 7 | 1 | 32 | |
| GSE54993 | RNF135 | 84282 | 2 | 3 | 65 | |
| GSE54994 | RNF135 | 84282 | 7 | 6 | 40 | |
| GSE60625 | RNF135 | 84282 | 4 | 0 | 7 | |
| GSE74703 | RNF135 | 84282 | 0 | 1 | 35 | |
| GSE74704 | RNF135 | 84282 | 6 | 2 | 12 | |
| TCGA | RNF135 | 84282 | 19 | 10 | 67 |
Total number of gains: 95; Total number of losses: 29; Total Number of normals: 364.
Somatic mutations of RNF135:
Generating mutation plots.
Highly correlated genes for RNF135:
Showing top 20/976 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF135 | PROSER1 | 0.800111 | 3 | 0 | 3 |
| RNF135 | C1orf56 | 0.795196 | 3 | 0 | 3 |
| RNF135 | N4BP2L2 | 0.79358 | 3 | 0 | 3 |
| RNF135 | GPBP1 | 0.776097 | 3 | 0 | 3 |
| RNF135 | SNX18 | 0.761217 | 3 | 0 | 3 |
| RNF135 | CDC16 | 0.752423 | 3 | 0 | 3 |
| RNF135 | DHX29 | 0.743238 | 4 | 0 | 4 |
| RNF135 | CCNYL1 | 0.738736 | 4 | 0 | 4 |
| RNF135 | CHCHD1 | 0.731667 | 3 | 0 | 3 |
| RNF135 | PDLIM2 | 0.730761 | 3 | 0 | 3 |
| RNF135 | MAU2 | 0.729801 | 6 | 0 | 5 |
| RNF135 | SETMAR | 0.729024 | 3 | 0 | 3 |
| RNF135 | CHP1 | 0.725686 | 4 | 0 | 4 |
| RNF135 | GOLGB1 | 0.725246 | 3 | 0 | 3 |
| RNF135 | ZRANB1 | 0.723165 | 3 | 0 | 3 |
| RNF135 | PPA1 | 0.722923 | 3 | 0 | 3 |
| RNF135 | TSPO | 0.721621 | 5 | 0 | 5 |
| RNF135 | EPB41L4A | 0.719658 | 3 | 0 | 3 |
| RNF135 | CAPNS1 | 0.718184 | 6 | 0 | 6 |
| RNF135 | PLEKHM1 | 0.715658 | 5 | 0 | 4 |
For details and further investigation, click here
