MRPS36

 

Full name: mitochondrial ribosomal protein S36 Alias Symbol: DC47|MRP-S36
Type: protein-coding gene Cytoband: 5q13.2
Entrez ID: 92259 HGNC ID: HGNC:16631 Ensembl Gene: ENSG00000134056 OMIM ID: 611996
Drug and gene relationship at DGIdb

 

Expression of MRPS36:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MRPS36 92259 224302_s_at -0.7968 0.0610
GSE26886 MRPS36 92259 224302_s_at -0.4171 0.0123
GSE45670 MRPS36 92259 224302_s_at -0.5171 0.0014
GSE53622 MRPS36 92259 10463 -0.9013 0.0000
GSE53624 MRPS36 92259 10463 -0.8135 0.0000
GSE63941 MRPS36 92259 224302_s_at 0.2414 0.4892
GSE77861 MRPS36 92259 224302_s_at -0.9670 0.0016
GSE97050 MRPS36 92259 A_23_P29575 -0.2620 0.2366
SRP007169 MRPS36 92259 RNAseq -1.5804 0.0001
SRP008496 MRPS36 92259 RNAseq -1.5882 0.0000
SRP064894 MRPS36 92259 RNAseq -0.7959 0.0005
SRP133303 MRPS36 92259 RNAseq -0.4747 0.0071
SRP159526 MRPS36 92259 RNAseq -0.8634 0.0456
SRP193095 MRPS36 92259 RNAseq -1.3298 0.0000
SRP219564 MRPS36 92259 RNAseq -1.2370 0.0000
TCGA MRPS36 92259 RNAseq -0.2683 0.0000

Upregulated datasets: 0; Downregulated datasets: 4.  


 

Survival by MRPS36 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of MRPS36:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MRPS36 92259 1 13 16
GSE20123 MRPS36 92259 1 13 16
GSE43470 MRPS36 92259 1 12 30
GSE46452 MRPS36 92259 0 28 31
GSE47630 MRPS36 92259 2 17 21
GSE54993 MRPS36 92259 8 1 61
GSE54994 MRPS36 92259 1 21 31
GSE60625 MRPS36 92259 0 0 11
GSE74703 MRPS36 92259 1 9 26
GSE74704 MRPS36 92259 1 6 13
TCGA MRPS36 92259 4 51 41

Total number of gains: 20; Total number of losses: 171; Total Number of normals: 297.  


 

Somatic mutations of MRPS36:

 

Generating mutation plots.

 

Highly correlated genes for MRPS36:

 

Showing top 20/1604 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MRPS36LRRFIP20.802751707
MRPS36RAB5A0.78722707
MRPS36CAB39L0.785575707
MRPS36FAM174A0.784012707
MRPS36DMXL10.783491807
MRPS36BLOC1S10.783342504
MRPS36EMC30.783241606
MRPS36CPEB30.779999606
MRPS36SREK1IP10.774199606
MRPS36KAT2B0.773687707
MRPS36PAIP2B0.773632606
MRPS36ANO100.772493606
MRPS36TRIP100.76979606
MRPS36UBE4B0.76829303
MRPS36MKRN20.767124505
MRPS36HSD17B40.760744707
MRPS36IK0.758608807
MRPS36DOCK90.758053707
MRPS36UBL30.7572606
MRPS36GOLGA40.756129505

For details and further investigation, click here