| Full name: inositol polyphosphate multikinase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10q21.1 | ||
| Entrez ID: 253430 | HGNC ID: HGNC:20739 | Ensembl Gene: ENSG00000151151 | OMIM ID: 609851 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of IPMK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IPMK | 253430 | 238739_at | -0.0636 | 0.9129 | |
| GSE26886 | IPMK | 253430 | 238739_at | -0.6688 | 0.0035 | |
| GSE45670 | IPMK | 253430 | 238739_at | -0.3491 | 0.0175 | |
| GSE53622 | IPMK | 253430 | 35391 | -0.3232 | 0.0154 | |
| GSE53624 | IPMK | 253430 | 35391 | -0.2718 | 0.0120 | |
| GSE63941 | IPMK | 253430 | 238739_at | -0.2411 | 0.6255 | |
| GSE77861 | IPMK | 253430 | 238739_at | -0.3266 | 0.1281 | |
| GSE97050 | IPMK | 253430 | A_23_P380371 | 0.5856 | 0.2575 | |
| SRP007169 | IPMK | 253430 | RNAseq | -0.9511 | 0.0637 | |
| SRP008496 | IPMK | 253430 | RNAseq | -1.1920 | 0.0004 | |
| SRP064894 | IPMK | 253430 | RNAseq | -0.7960 | 0.0372 | |
| SRP133303 | IPMK | 253430 | RNAseq | -0.3137 | 0.1573 | |
| SRP159526 | IPMK | 253430 | RNAseq | 0.5942 | 0.3590 | |
| SRP193095 | IPMK | 253430 | RNAseq | 0.1596 | 0.5615 | |
| SRP219564 | IPMK | 253430 | RNAseq | -0.0240 | 0.9730 | |
| TCGA | IPMK | 253430 | RNAseq | 0.0531 | 0.6293 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by IPMK expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IPMK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IPMK | 253430 | 2 | 6 | 22 | |
| GSE20123 | IPMK | 253430 | 2 | 6 | 22 | |
| GSE43470 | IPMK | 253430 | 2 | 5 | 36 | |
| GSE46452 | IPMK | 253430 | 0 | 12 | 47 | |
| GSE47630 | IPMK | 253430 | 4 | 12 | 24 | |
| GSE54993 | IPMK | 253430 | 9 | 0 | 61 | |
| GSE54994 | IPMK | 253430 | 3 | 10 | 40 | |
| GSE60625 | IPMK | 253430 | 0 | 0 | 11 | |
| GSE74703 | IPMK | 253430 | 2 | 3 | 31 | |
| GSE74704 | IPMK | 253430 | 1 | 4 | 15 | |
| TCGA | IPMK | 253430 | 10 | 23 | 63 |
Total number of gains: 35; Total number of losses: 81; Total Number of normals: 372.
Somatic mutations of IPMK:
Generating mutation plots.
Highly correlated genes for IPMK:
Showing top 20/774 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IPMK | RNFT1 | 0.821426 | 3 | 0 | 3 |
| IPMK | SPIN4 | 0.807225 | 3 | 0 | 3 |
| IPMK | MAP4K5 | 0.804253 | 3 | 0 | 3 |
| IPMK | MTIF2 | 0.789729 | 3 | 0 | 3 |
| IPMK | ZCCHC10 | 0.777772 | 4 | 0 | 4 |
| IPMK | FBXW7 | 0.752414 | 3 | 0 | 3 |
| IPMK | COMMD8 | 0.750623 | 4 | 0 | 4 |
| IPMK | ZNF92 | 0.749429 | 3 | 0 | 3 |
| IPMK | ACBD3 | 0.733641 | 4 | 0 | 4 |
| IPMK | PSMC6 | 0.730068 | 3 | 0 | 3 |
| IPMK | LRRC40 | 0.729278 | 3 | 0 | 3 |
| IPMK | DHX29 | 0.727461 | 4 | 0 | 4 |
| IPMK | WDFY1 | 0.727341 | 3 | 0 | 3 |
| IPMK | THUMPD3 | 0.727156 | 4 | 0 | 4 |
| IPMK | ACSL3 | 0.724721 | 4 | 0 | 4 |
| IPMK | KCMF1 | 0.724183 | 4 | 0 | 4 |
| IPMK | ZMYM2 | 0.722998 | 4 | 0 | 3 |
| IPMK | ALG13 | 0.72206 | 3 | 0 | 3 |
| IPMK | SNAP29 | 0.721355 | 3 | 0 | 3 |
| IPMK | MRPL35 | 0.721138 | 3 | 0 | 3 |
For details and further investigation, click here
