| Full name: angiopoietin like 4 | Alias Symbol: pp1158|PGAR|ARP4|HFARP|FIAF|NL2 | ||
| Type: protein-coding gene | Cytoband: 19p13.2 | ||
| Entrez ID: 51129 | HGNC ID: HGNC:16039 | Ensembl Gene: ENSG00000167772 | OMIM ID: 605910 |
| Drug and gene relationship at DGIdb | |||
ANGPTL4 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa03320 | PPAR signaling pathway |
Expression of ANGPTL4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANGPTL4 | 51129 | 221009_s_at | -0.7293 | 0.2707 | |
| GSE20347 | ANGPTL4 | 51129 | 221009_s_at | -0.0185 | 0.9283 | |
| GSE23400 | ANGPTL4 | 51129 | 221009_s_at | -0.0624 | 0.5160 | |
| GSE26886 | ANGPTL4 | 51129 | 221009_s_at | -0.6309 | 0.2370 | |
| GSE29001 | ANGPTL4 | 51129 | 221009_s_at | -0.3583 | 0.3935 | |
| GSE38129 | ANGPTL4 | 51129 | 221009_s_at | 0.0703 | 0.7227 | |
| GSE45670 | ANGPTL4 | 51129 | 221009_s_at | 0.4102 | 0.2104 | |
| GSE53622 | ANGPTL4 | 51129 | 14247 | -0.2516 | 0.0683 | |
| GSE53624 | ANGPTL4 | 51129 | 14247 | -0.3479 | 0.0018 | |
| GSE63941 | ANGPTL4 | 51129 | 221009_s_at | -0.6138 | 0.0996 | |
| GSE77861 | ANGPTL4 | 51129 | 223333_s_at | 0.2658 | 0.5579 | |
| GSE97050 | ANGPTL4 | 51129 | A_33_P3295358 | 0.2365 | 0.4892 | |
| SRP007169 | ANGPTL4 | 51129 | RNAseq | -0.3611 | 0.4900 | |
| SRP008496 | ANGPTL4 | 51129 | RNAseq | -1.5703 | 0.0001 | |
| SRP064894 | ANGPTL4 | 51129 | RNAseq | 0.4486 | 0.3062 | |
| SRP133303 | ANGPTL4 | 51129 | RNAseq | 0.4898 | 0.2854 | |
| SRP159526 | ANGPTL4 | 51129 | RNAseq | -1.8273 | 0.0001 | |
| SRP193095 | ANGPTL4 | 51129 | RNAseq | -0.2127 | 0.5816 | |
| SRP219564 | ANGPTL4 | 51129 | RNAseq | -0.4749 | 0.4437 | |
| TCGA | ANGPTL4 | 51129 | RNAseq | -0.1368 | 0.4600 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ANGPTL4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANGPTL4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANGPTL4 | 51129 | 4 | 3 | 23 | |
| GSE20123 | ANGPTL4 | 51129 | 3 | 2 | 25 | |
| GSE43470 | ANGPTL4 | 51129 | 2 | 6 | 35 | |
| GSE46452 | ANGPTL4 | 51129 | 47 | 1 | 11 | |
| GSE47630 | ANGPTL4 | 51129 | 5 | 7 | 28 | |
| GSE54993 | ANGPTL4 | 51129 | 16 | 3 | 51 | |
| GSE54994 | ANGPTL4 | 51129 | 6 | 14 | 33 | |
| GSE60625 | ANGPTL4 | 51129 | 9 | 0 | 2 | |
| GSE74703 | ANGPTL4 | 51129 | 2 | 4 | 30 | |
| GSE74704 | ANGPTL4 | 51129 | 0 | 2 | 18 | |
| TCGA | ANGPTL4 | 51129 | 10 | 19 | 67 |
Total number of gains: 104; Total number of losses: 61; Total Number of normals: 323.
Somatic mutations of ANGPTL4:
Generating mutation plots.
Highly correlated genes for ANGPTL4:
Showing top 20/176 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANGPTL4 | STK32B | 0.788187 | 3 | 0 | 3 |
| ANGPTL4 | A1BG | 0.772486 | 3 | 0 | 3 |
| ANGPTL4 | LYSMD3 | 0.771803 | 3 | 0 | 3 |
| ANGPTL4 | EFEMP2 | 0.764081 | 3 | 0 | 3 |
| ANGPTL4 | SEC23A | 0.755104 | 3 | 0 | 3 |
| ANGPTL4 | DHX29 | 0.753661 | 3 | 0 | 3 |
| ANGPTL4 | RASA1 | 0.751381 | 3 | 0 | 3 |
| ANGPTL4 | DOK6 | 0.744262 | 3 | 0 | 3 |
| ANGPTL4 | BAG5 | 0.743496 | 3 | 0 | 3 |
| ANGPTL4 | CLEC11A | 0.735094 | 3 | 0 | 3 |
| ANGPTL4 | SLC2A3 | 0.732551 | 3 | 0 | 3 |
| ANGPTL4 | YLPM1 | 0.726899 | 3 | 0 | 3 |
| ANGPTL4 | CHN1 | 0.720297 | 3 | 0 | 3 |
| ANGPTL4 | AK3 | 0.719818 | 3 | 0 | 3 |
| ANGPTL4 | FOXC2 | 0.716751 | 3 | 0 | 3 |
| ANGPTL4 | PLEKHO2 | 0.715022 | 3 | 0 | 3 |
| ANGPTL4 | MLIP | 0.713125 | 3 | 0 | 3 |
| ANGPTL4 | EPB41L3 | 0.712007 | 3 | 0 | 3 |
| ANGPTL4 | ST3GAL2 | 0.70145 | 3 | 0 | 3 |
| ANGPTL4 | PRKAR1A | 0.699569 | 3 | 0 | 3 |
For details and further investigation, click here
