| Full name: impact RWD domain protein | Alias Symbol: RWDD5 | ||
| Type: protein-coding gene | Cytoband: 18q11.2 | ||
| Entrez ID: 55364 | HGNC ID: HGNC:20387 | Ensembl Gene: ENSG00000154059 | OMIM ID: 615319 |
| Drug and gene relationship at DGIdb | |||
Expression of IMPACT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IMPACT | 55364 | 222698_s_at | -0.3630 | 0.3410 | |
| GSE20347 | IMPACT | 55364 | 218637_at | 0.0233 | 0.9253 | |
| GSE23400 | IMPACT | 55364 | 218637_at | 0.2485 | 0.0008 | |
| GSE26886 | IMPACT | 55364 | 222698_s_at | -0.9748 | 0.0005 | |
| GSE29001 | IMPACT | 55364 | 218637_at | 0.3149 | 0.5173 | |
| GSE38129 | IMPACT | 55364 | 218637_at | 0.1667 | 0.2702 | |
| GSE45670 | IMPACT | 55364 | 218637_at | -0.1273 | 0.6139 | |
| GSE53622 | IMPACT | 55364 | 68962 | 0.0710 | 0.4139 | |
| GSE53624 | IMPACT | 55364 | 68962 | 0.1944 | 0.0155 | |
| GSE63941 | IMPACT | 55364 | 222698_s_at | -0.1935 | 0.7665 | |
| GSE77861 | IMPACT | 55364 | 222698_s_at | 0.3936 | 0.2716 | |
| GSE97050 | IMPACT | 55364 | A_24_P108291 | -0.2417 | 0.3185 | |
| SRP007169 | IMPACT | 55364 | RNAseq | 0.7813 | 0.0325 | |
| SRP008496 | IMPACT | 55364 | RNAseq | 0.6327 | 0.0065 | |
| SRP064894 | IMPACT | 55364 | RNAseq | -0.1130 | 0.5846 | |
| SRP133303 | IMPACT | 55364 | RNAseq | 0.2015 | 0.2687 | |
| SRP159526 | IMPACT | 55364 | RNAseq | 0.3208 | 0.2415 | |
| SRP193095 | IMPACT | 55364 | RNAseq | -0.1904 | 0.1145 | |
| SRP219564 | IMPACT | 55364 | RNAseq | 0.0855 | 0.7305 | |
| TCGA | IMPACT | 55364 | RNAseq | 0.0362 | 0.5584 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IMPACT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IMPACT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IMPACT | 55364 | 4 | 5 | 21 | |
| GSE20123 | IMPACT | 55364 | 3 | 5 | 22 | |
| GSE43470 | IMPACT | 55364 | 1 | 1 | 41 | |
| GSE46452 | IMPACT | 55364 | 3 | 24 | 32 | |
| GSE47630 | IMPACT | 55364 | 7 | 18 | 15 | |
| GSE54993 | IMPACT | 55364 | 7 | 1 | 62 | |
| GSE54994 | IMPACT | 55364 | 2 | 14 | 37 | |
| GSE60625 | IMPACT | 55364 | 0 | 4 | 7 | |
| GSE74703 | IMPACT | 55364 | 1 | 1 | 34 | |
| GSE74704 | IMPACT | 55364 | 2 | 4 | 14 | |
| TCGA | IMPACT | 55364 | 15 | 30 | 51 |
Total number of gains: 45; Total number of losses: 107; Total Number of normals: 336.
Somatic mutations of IMPACT:
Generating mutation plots.
Highly correlated genes for IMPACT:
Showing top 20/655 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IMPACT | CPT2 | 0.859448 | 3 | 0 | 3 |
| IMPACT | CBLL1 | 0.831273 | 3 | 0 | 3 |
| IMPACT | TJP1 | 0.830981 | 3 | 0 | 3 |
| IMPACT | RREB1 | 0.828303 | 3 | 0 | 3 |
| IMPACT | LYSMD3 | 0.825121 | 3 | 0 | 3 |
| IMPACT | USP6NL | 0.824605 | 3 | 0 | 3 |
| IMPACT | VPS4B | 0.820838 | 3 | 0 | 3 |
| IMPACT | EEA1 | 0.818385 | 3 | 0 | 3 |
| IMPACT | BRK1 | 0.816511 | 3 | 0 | 3 |
| IMPACT | EMP2 | 0.811875 | 3 | 0 | 3 |
| IMPACT | MTPN | 0.811783 | 3 | 0 | 3 |
| IMPACT | SCOC | 0.811359 | 3 | 0 | 3 |
| IMPACT | RNF141 | 0.81018 | 3 | 0 | 3 |
| IMPACT | CCNG2 | 0.808597 | 3 | 0 | 3 |
| IMPACT | STXBP5 | 0.806052 | 3 | 0 | 3 |
| IMPACT | THAP2 | 0.804578 | 3 | 0 | 3 |
| IMPACT | CHMP5 | 0.804192 | 3 | 0 | 3 |
| IMPACT | LRRFIP2 | 0.79917 | 3 | 0 | 3 |
| IMPACT | PKN2 | 0.791257 | 3 | 0 | 3 |
| IMPACT | SPAG16 | 0.789684 | 3 | 0 | 3 |
For details and further investigation, click here
