| Full name: chromosome 11 open reading frame 54 | Alias Symbol: PTD012 | ||
| Type: protein-coding gene | Cytoband: 11q21 | ||
| Entrez ID: 28970 | HGNC ID: HGNC:30204 | Ensembl Gene: ENSG00000182919 | OMIM ID: 615810 |
Expression of C11orf54:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C11orf54 | 28970 | 223268_at | -0.7191 | 0.1498 | |
| GSE26886 | C11orf54 | 28970 | 223268_at | -0.6368 | 0.1154 | |
| GSE45670 | C11orf54 | 28970 | 223268_at | -0.5682 | 0.0309 | |
| GSE53622 | C11orf54 | 28970 | 427 | -0.4643 | 0.0000 | |
| GSE53624 | C11orf54 | 28970 | 25193 | -0.5635 | 0.0000 | |
| GSE63941 | C11orf54 | 28970 | 229851_s_at | 0.4218 | 0.4149 | |
| GSE77861 | C11orf54 | 28970 | 1559623_at | -0.0982 | 0.1968 | |
| GSE97050 | C11orf54 | 28970 | A_23_P202750 | 0.1496 | 0.6594 | |
| SRP007169 | C11orf54 | 28970 | RNAseq | -0.3602 | 0.4568 | |
| SRP008496 | C11orf54 | 28970 | RNAseq | -0.5031 | 0.0778 | |
| SRP064894 | C11orf54 | 28970 | RNAseq | -0.5404 | 0.0115 | |
| SRP133303 | C11orf54 | 28970 | RNAseq | -0.6212 | 0.0004 | |
| SRP159526 | C11orf54 | 28970 | RNAseq | -0.4970 | 0.1468 | |
| SRP193095 | C11orf54 | 28970 | RNAseq | -1.1668 | 0.0000 | |
| SRP219564 | C11orf54 | 28970 | RNAseq | -0.6106 | 0.0304 | |
| TCGA | C11orf54 | 28970 | RNAseq | -0.4905 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by C11orf54 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C11orf54:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C11orf54 | 28970 | 3 | 10 | 17 | |
| GSE20123 | C11orf54 | 28970 | 3 | 10 | 17 | |
| GSE43470 | C11orf54 | 28970 | 2 | 5 | 36 | |
| GSE46452 | C11orf54 | 28970 | 5 | 24 | 30 | |
| GSE47630 | C11orf54 | 28970 | 2 | 19 | 19 | |
| GSE54993 | C11orf54 | 28970 | 8 | 2 | 60 | |
| GSE54994 | C11orf54 | 28970 | 5 | 19 | 29 | |
| GSE60625 | C11orf54 | 28970 | 0 | 3 | 8 | |
| GSE74703 | C11orf54 | 28970 | 1 | 4 | 31 | |
| GSE74704 | C11orf54 | 28970 | 3 | 6 | 11 | |
| TCGA | C11orf54 | 28970 | 11 | 42 | 43 |
Total number of gains: 43; Total number of losses: 144; Total Number of normals: 301.
Somatic mutations of C11orf54:
Generating mutation plots.
Highly correlated genes for C11orf54:
Showing top 20/524 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C11orf54 | SNX14 | 0.835151 | 3 | 0 | 3 |
| C11orf54 | WDR20 | 0.829967 | 3 | 0 | 3 |
| C11orf54 | DHX29 | 0.750156 | 4 | 0 | 4 |
| C11orf54 | SPTLC3 | 0.749531 | 3 | 0 | 3 |
| C11orf54 | TRIP4 | 0.748199 | 3 | 0 | 3 |
| C11orf54 | BDP1 | 0.736711 | 4 | 0 | 4 |
| C11orf54 | MRFAP1L1 | 0.735337 | 3 | 0 | 3 |
| C11orf54 | VPS29 | 0.732988 | 4 | 0 | 4 |
| C11orf54 | MTX3 | 0.72969 | 3 | 0 | 3 |
| C11orf54 | TMEM19 | 0.72527 | 4 | 0 | 4 |
| C11orf54 | SLC22A15 | 0.720229 | 4 | 0 | 3 |
| C11orf54 | UBE4A | 0.719802 | 3 | 0 | 3 |
| C11orf54 | SNX19 | 0.714965 | 3 | 0 | 3 |
| C11orf54 | SGMS2 | 0.710447 | 3 | 0 | 3 |
| C11orf54 | COPG2 | 0.708586 | 3 | 0 | 3 |
| C11orf54 | COPS6 | 0.705319 | 3 | 0 | 3 |
| C11orf54 | ITPRIP | 0.702954 | 3 | 0 | 3 |
| C11orf54 | COMMD10 | 0.702629 | 4 | 0 | 3 |
| C11orf54 | ATG2B | 0.701279 | 4 | 0 | 3 |
| C11orf54 | MEGF9 | 0.696102 | 4 | 0 | 4 |
For details and further investigation, click here
