| Full name: pentatricopeptide repeat domain 2 | Alias Symbol: FLJ12598 | ||
| Type: protein-coding gene | Cytoband: 5q13.2 | ||
| Entrez ID: 79810 | HGNC ID: HGNC:25734 | Ensembl Gene: ENSG00000049883 | OMIM ID: 615484 |
| Drug and gene relationship at DGIdb | |||
Expression of PTCD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PTCD2 | 79810 | 1555910_at | -0.4177 | 0.5435 | |
| GSE20347 | PTCD2 | 79810 | 219658_at | -0.1058 | 0.4499 | |
| GSE23400 | PTCD2 | 79810 | 219658_at | -0.0378 | 0.4550 | |
| GSE26886 | PTCD2 | 79810 | 1555910_at | -0.2340 | 0.4474 | |
| GSE29001 | PTCD2 | 79810 | 219658_at | 0.1357 | 0.3871 | |
| GSE38129 | PTCD2 | 79810 | 219658_at | -0.1990 | 0.2415 | |
| GSE45670 | PTCD2 | 79810 | 1555910_at | 0.0598 | 0.7540 | |
| GSE53622 | PTCD2 | 79810 | 21356 | -0.4414 | 0.0000 | |
| GSE53624 | PTCD2 | 79810 | 21356 | -0.1861 | 0.0191 | |
| GSE63941 | PTCD2 | 79810 | 1555910_at | -0.2537 | 0.6846 | |
| GSE77861 | PTCD2 | 79810 | 219658_at | 0.0035 | 0.9862 | |
| GSE97050 | PTCD2 | 79810 | A_24_P191847 | 0.0181 | 0.9543 | |
| SRP007169 | PTCD2 | 79810 | RNAseq | -0.0549 | 0.8998 | |
| SRP008496 | PTCD2 | 79810 | RNAseq | 0.2512 | 0.5380 | |
| SRP064894 | PTCD2 | 79810 | RNAseq | 0.0259 | 0.8514 | |
| SRP133303 | PTCD2 | 79810 | RNAseq | 0.0324 | 0.8460 | |
| SRP159526 | PTCD2 | 79810 | RNAseq | -0.0295 | 0.9476 | |
| SRP193095 | PTCD2 | 79810 | RNAseq | -0.2913 | 0.0213 | |
| SRP219564 | PTCD2 | 79810 | RNAseq | -0.3185 | 0.4592 | |
| TCGA | PTCD2 | 79810 | RNAseq | -0.0040 | 0.9570 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PTCD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PTCD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PTCD2 | 79810 | 1 | 13 | 16 | |
| GSE20123 | PTCD2 | 79810 | 1 | 13 | 16 | |
| GSE43470 | PTCD2 | 79810 | 1 | 13 | 29 | |
| GSE46452 | PTCD2 | 79810 | 0 | 28 | 31 | |
| GSE47630 | PTCD2 | 79810 | 1 | 19 | 20 | |
| GSE54993 | PTCD2 | 79810 | 8 | 1 | 61 | |
| GSE54994 | PTCD2 | 79810 | 1 | 19 | 33 | |
| GSE60625 | PTCD2 | 79810 | 0 | 0 | 11 | |
| GSE74703 | PTCD2 | 79810 | 1 | 9 | 26 | |
| GSE74704 | PTCD2 | 79810 | 1 | 6 | 13 | |
| TCGA | PTCD2 | 79810 | 4 | 51 | 41 |
Total number of gains: 19; Total number of losses: 172; Total Number of normals: 297.
Somatic mutations of PTCD2:
Generating mutation plots.
Highly correlated genes for PTCD2:
Showing top 20/225 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PTCD2 | LYSMD3 | 0.800745 | 3 | 0 | 3 |
| PTCD2 | MRPL45 | 0.799863 | 3 | 0 | 3 |
| PTCD2 | PSMD7 | 0.776163 | 3 | 0 | 3 |
| PTCD2 | SEC24B | 0.770326 | 3 | 0 | 3 |
| PTCD2 | HERPUD2 | 0.770301 | 3 | 0 | 3 |
| PTCD2 | TTC8 | 0.757362 | 3 | 0 | 3 |
| PTCD2 | DHX29 | 0.75341 | 4 | 0 | 4 |
| PTCD2 | SLC35E3 | 0.752005 | 3 | 0 | 3 |
| PTCD2 | ZZZ3 | 0.734866 | 3 | 0 | 3 |
| PTCD2 | OSBPL8 | 0.723889 | 3 | 0 | 3 |
| PTCD2 | LANCL1 | 0.718203 | 4 | 0 | 3 |
| PTCD2 | ALDH6A1 | 0.710517 | 3 | 0 | 3 |
| PTCD2 | SCAPER | 0.708694 | 4 | 0 | 3 |
| PTCD2 | CLCC1 | 0.7078 | 3 | 0 | 3 |
| PTCD2 | PHF20 | 0.698604 | 3 | 0 | 3 |
| PTCD2 | CCDC66 | 0.698564 | 3 | 0 | 3 |
| PTCD2 | AGL | 0.698446 | 4 | 0 | 4 |
| PTCD2 | GSTZ1 | 0.694708 | 3 | 0 | 3 |
| PTCD2 | LGALSL | 0.692355 | 3 | 0 | 3 |
| PTCD2 | RUFY3 | 0.689216 | 3 | 0 | 3 |
For details and further investigation, click here
