| Full name: autophagy related 2B | Alias Symbol: FLJ10242 | ||
| Type: protein-coding gene | Cytoband: 14q32.2 | ||
| Entrez ID: 55102 | HGNC ID: HGNC:20187 | Ensembl Gene: ENSG00000066739 | OMIM ID: 616226 |
| Drug and gene relationship at DGIdb | |||
Expression of ATG2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATG2B | 55102 | 226684_at | -0.1395 | 0.7986 | |
| GSE20347 | ATG2B | 55102 | 219164_s_at | -0.0087 | 0.9789 | |
| GSE23400 | ATG2B | 55102 | 219164_s_at | 0.1877 | 0.0016 | |
| GSE26886 | ATG2B | 55102 | 226684_at | -0.3852 | 0.1238 | |
| GSE29001 | ATG2B | 55102 | 219164_s_at | 0.1667 | 0.5572 | |
| GSE38129 | ATG2B | 55102 | 219164_s_at | 0.0939 | 0.6117 | |
| GSE45670 | ATG2B | 55102 | 226684_at | -0.3841 | 0.0012 | |
| GSE53622 | ATG2B | 55102 | 3258 | -0.0976 | 0.2064 | |
| GSE53624 | ATG2B | 55102 | 3258 | -0.1907 | 0.1283 | |
| GSE63941 | ATG2B | 55102 | 226684_at | -0.3471 | 0.5158 | |
| GSE77861 | ATG2B | 55102 | 226684_at | -0.3108 | 0.3351 | |
| GSE97050 | ATG2B | 55102 | A_33_P3342160 | -0.0460 | 0.8999 | |
| SRP007169 | ATG2B | 55102 | RNAseq | 0.3452 | 0.3808 | |
| SRP008496 | ATG2B | 55102 | RNAseq | 0.3733 | 0.1112 | |
| SRP064894 | ATG2B | 55102 | RNAseq | -0.3461 | 0.2027 | |
| SRP133303 | ATG2B | 55102 | RNAseq | 0.0520 | 0.7287 | |
| SRP159526 | ATG2B | 55102 | RNAseq | -0.2438 | 0.2986 | |
| SRP193095 | ATG2B | 55102 | RNAseq | -0.1740 | 0.0598 | |
| SRP219564 | ATG2B | 55102 | RNAseq | -0.0898 | 0.7672 | |
| TCGA | ATG2B | 55102 | RNAseq | -0.1538 | 0.0020 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ATG2B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATG2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATG2B | 55102 | 10 | 4 | 16 | |
| GSE20123 | ATG2B | 55102 | 10 | 3 | 17 | |
| GSE43470 | ATG2B | 55102 | 8 | 3 | 32 | |
| GSE46452 | ATG2B | 55102 | 17 | 3 | 39 | |
| GSE47630 | ATG2B | 55102 | 11 | 8 | 21 | |
| GSE54993 | ATG2B | 55102 | 3 | 8 | 59 | |
| GSE54994 | ATG2B | 55102 | 21 | 4 | 28 | |
| GSE60625 | ATG2B | 55102 | 0 | 2 | 9 | |
| GSE74703 | ATG2B | 55102 | 6 | 3 | 27 | |
| GSE74704 | ATG2B | 55102 | 6 | 3 | 11 | |
| TCGA | ATG2B | 55102 | 30 | 19 | 47 |
Total number of gains: 122; Total number of losses: 60; Total Number of normals: 306.
Somatic mutations of ATG2B:
Generating mutation plots.
Highly correlated genes for ATG2B:
Showing top 20/434 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATG2B | RNF144B | 0.843822 | 3 | 0 | 3 |
| ATG2B | DHX29 | 0.785528 | 4 | 0 | 4 |
| ATG2B | RRAGA | 0.778247 | 3 | 0 | 3 |
| ATG2B | DENND4C | 0.777711 | 3 | 0 | 3 |
| ATG2B | PPWD1 | 0.769276 | 3 | 0 | 3 |
| ATG2B | CASP4 | 0.762181 | 3 | 0 | 3 |
| ATG2B | THAP2 | 0.760715 | 3 | 0 | 3 |
| ATG2B | CUL4B | 0.753774 | 3 | 0 | 3 |
| ATG2B | TMEM126A | 0.752903 | 3 | 0 | 3 |
| ATG2B | WDR41 | 0.752077 | 3 | 0 | 3 |
| ATG2B | SPIN4 | 0.751221 | 3 | 0 | 3 |
| ATG2B | FAM126A | 0.750151 | 3 | 0 | 3 |
| ATG2B | CMTM4 | 0.748728 | 3 | 0 | 3 |
| ATG2B | RASA2 | 0.745965 | 3 | 0 | 3 |
| ATG2B | RASA1 | 0.742315 | 4 | 0 | 4 |
| ATG2B | COMMD8 | 0.741699 | 3 | 0 | 3 |
| ATG2B | C1orf50 | 0.739477 | 3 | 0 | 3 |
| ATG2B | ZFYVE16 | 0.73277 | 5 | 0 | 5 |
| ATG2B | TRMT1L | 0.731024 | 3 | 0 | 3 |
| ATG2B | ARL10 | 0.727533 | 3 | 0 | 3 |
For details and further investigation, click here
