| Full name: DEAH-box helicase 32 (putative) | Alias Symbol: FLJ10889|FLJ10694|DHLP1 | ||
| Type: protein-coding gene | Cytoband: 10q26.2 | ||
| Entrez ID: 55760 | HGNC ID: HGNC:16717 | Ensembl Gene: ENSG00000089876 | OMIM ID: 607960 |
| Drug and gene relationship at DGIdb | |||
Expression of DHX32:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DHX32 | 55760 | 218198_at | -0.3720 | 0.4729 | |
| GSE20347 | DHX32 | 55760 | 218198_at | -0.4446 | 0.0001 | |
| GSE23400 | DHX32 | 55760 | 218198_at | -0.3336 | 0.0000 | |
| GSE26886 | DHX32 | 55760 | 218198_at | -0.6729 | 0.0000 | |
| GSE29001 | DHX32 | 55760 | 218198_at | -0.8863 | 0.0025 | |
| GSE38129 | DHX32 | 55760 | 218198_at | -0.3838 | 0.0041 | |
| GSE45670 | DHX32 | 55760 | 218198_at | -0.3240 | 0.0448 | |
| GSE53622 | DHX32 | 55760 | 101594 | -0.5172 | 0.0000 | |
| GSE53624 | DHX32 | 55760 | 9284 | -0.9541 | 0.0000 | |
| GSE63941 | DHX32 | 55760 | 218198_at | 0.1034 | 0.7605 | |
| GSE77861 | DHX32 | 55760 | 218198_at | -0.2585 | 0.1352 | |
| GSE97050 | DHX32 | 55760 | A_23_P47004 | -0.3402 | 0.5076 | |
| SRP007169 | DHX32 | 55760 | RNAseq | -1.3043 | 0.0032 | |
| SRP008496 | DHX32 | 55760 | RNAseq | -1.2198 | 0.0000 | |
| SRP064894 | DHX32 | 55760 | RNAseq | -1.1832 | 0.0000 | |
| SRP133303 | DHX32 | 55760 | RNAseq | -0.4472 | 0.0150 | |
| SRP159526 | DHX32 | 55760 | RNAseq | -0.6717 | 0.0897 | |
| SRP193095 | DHX32 | 55760 | RNAseq | -0.7850 | 0.0000 | |
| SRP219564 | DHX32 | 55760 | RNAseq | -0.7692 | 0.0688 | |
| TCGA | DHX32 | 55760 | RNAseq | -0.1637 | 0.0019 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by DHX32 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DHX32:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DHX32 | 55760 | 2 | 6 | 22 | |
| GSE20123 | DHX32 | 55760 | 2 | 6 | 22 | |
| GSE43470 | DHX32 | 55760 | 0 | 10 | 33 | |
| GSE46452 | DHX32 | 55760 | 0 | 11 | 48 | |
| GSE47630 | DHX32 | 55760 | 2 | 14 | 24 | |
| GSE54993 | DHX32 | 55760 | 9 | 1 | 60 | |
| GSE54994 | DHX32 | 55760 | 1 | 9 | 43 | |
| GSE60625 | DHX32 | 55760 | 0 | 0 | 11 | |
| GSE74703 | DHX32 | 55760 | 0 | 6 | 30 | |
| GSE74704 | DHX32 | 55760 | 2 | 2 | 16 | |
| TCGA | DHX32 | 55760 | 7 | 27 | 62 |
Total number of gains: 25; Total number of losses: 92; Total Number of normals: 371.
Somatic mutations of DHX32:
Generating mutation plots.
Highly correlated genes for DHX32:
Showing top 20/1453 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DHX32 | TMEM167B | 0.788156 | 3 | 0 | 3 |
| DHX32 | TPD52L2 | 0.781505 | 3 | 0 | 3 |
| DHX32 | ANO8 | 0.756254 | 4 | 0 | 4 |
| DHX32 | CCDC85C | 0.74893 | 3 | 0 | 3 |
| DHX32 | TOM1 | 0.745238 | 10 | 0 | 9 |
| DHX32 | PDIK1L | 0.743935 | 3 | 0 | 3 |
| DHX32 | MYOF | 0.742418 | 3 | 0 | 3 |
| DHX32 | PLEKHM1 | 0.742199 | 10 | 0 | 10 |
| DHX32 | CCNYL1 | 0.736153 | 5 | 0 | 4 |
| DHX32 | SH3GL1 | 0.734995 | 10 | 0 | 10 |
| DHX32 | RAB11A | 0.731731 | 11 | 0 | 10 |
| DHX32 | BLOC1S2 | 0.731008 | 6 | 0 | 5 |
| DHX32 | S100A16 | 0.73083 | 5 | 0 | 5 |
| DHX32 | EVPL | 0.728026 | 9 | 0 | 9 |
| DHX32 | GRPEL2 | 0.727987 | 7 | 0 | 7 |
| DHX32 | PAIP2 | 0.725736 | 3 | 0 | 3 |
| DHX32 | TRAPPC6B | 0.725168 | 3 | 0 | 3 |
| DHX32 | SLC25A51 | 0.717102 | 3 | 0 | 3 |
| DHX32 | CCDC25 | 0.713607 | 3 | 0 | 3 |
| DHX32 | SLC46A2 | 0.71279 | 7 | 0 | 7 |
For details and further investigation, click here
