| Full name: trafficking protein particle complex 6B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q21.1 | ||
| Entrez ID: 122553 | HGNC ID: HGNC:23066 | Ensembl Gene: ENSG00000182400 | OMIM ID: 610397 |
| Drug and gene relationship at DGIdb | |||
Expression of TRAPPC6B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRAPPC6B | 122553 | 225537_at | 0.0411 | 0.9740 | |
| GSE26886 | TRAPPC6B | 122553 | 225537_at | -1.0374 | 0.0006 | |
| GSE45670 | TRAPPC6B | 122553 | 225537_at | 0.0091 | 0.9551 | |
| GSE53622 | TRAPPC6B | 122553 | 59256 | -0.1389 | 0.0208 | |
| GSE53624 | TRAPPC6B | 122553 | 59256 | -0.2161 | 0.0002 | |
| GSE63941 | TRAPPC6B | 122553 | 225537_at | -0.2006 | 0.6964 | |
| GSE77861 | TRAPPC6B | 122553 | 225537_at | -0.2466 | 0.6259 | |
| GSE97050 | TRAPPC6B | 122553 | A_24_P942132 | 0.3208 | 0.3051 | |
| SRP007169 | TRAPPC6B | 122553 | RNAseq | -0.3421 | 0.3588 | |
| SRP008496 | TRAPPC6B | 122553 | RNAseq | -0.2379 | 0.3149 | |
| SRP064894 | TRAPPC6B | 122553 | RNAseq | 0.1515 | 0.3215 | |
| SRP133303 | TRAPPC6B | 122553 | RNAseq | 0.7989 | 0.0389 | |
| SRP159526 | TRAPPC6B | 122553 | RNAseq | -0.4402 | 0.0495 | |
| SRP193095 | TRAPPC6B | 122553 | RNAseq | -0.2839 | 0.0164 | |
| SRP219564 | TRAPPC6B | 122553 | RNAseq | -0.0993 | 0.6893 | |
| TCGA | TRAPPC6B | 122553 | RNAseq | 0.0021 | 0.9685 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TRAPPC6B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRAPPC6B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRAPPC6B | 122553 | 9 | 5 | 16 | |
| GSE20123 | TRAPPC6B | 122553 | 9 | 5 | 16 | |
| GSE43470 | TRAPPC6B | 122553 | 9 | 3 | 31 | |
| GSE46452 | TRAPPC6B | 122553 | 18 | 2 | 39 | |
| GSE47630 | TRAPPC6B | 122553 | 11 | 10 | 19 | |
| GSE54993 | TRAPPC6B | 122553 | 3 | 9 | 58 | |
| GSE54994 | TRAPPC6B | 122553 | 19 | 5 | 29 | |
| GSE60625 | TRAPPC6B | 122553 | 0 | 2 | 9 | |
| GSE74703 | TRAPPC6B | 122553 | 8 | 3 | 25 | |
| GSE74704 | TRAPPC6B | 122553 | 4 | 3 | 13 | |
| TCGA | TRAPPC6B | 122553 | 35 | 13 | 48 |
Total number of gains: 125; Total number of losses: 60; Total Number of normals: 303.
Somatic mutations of TRAPPC6B:
Generating mutation plots.
Highly correlated genes for TRAPPC6B:
Showing top 20/331 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRAPPC6B | PSMG2 | 0.820871 | 3 | 0 | 3 |
| TRAPPC6B | RRAGC | 0.819318 | 3 | 0 | 3 |
| TRAPPC6B | MED8 | 0.804822 | 3 | 0 | 3 |
| TRAPPC6B | CHMP5 | 0.802565 | 3 | 0 | 3 |
| TRAPPC6B | ZNF268 | 0.800255 | 3 | 0 | 3 |
| TRAPPC6B | SPIN4 | 0.794372 | 3 | 0 | 3 |
| TRAPPC6B | ZSCAN29 | 0.793331 | 3 | 0 | 3 |
| TRAPPC6B | BTRC | 0.7842 | 3 | 0 | 3 |
| TRAPPC6B | MRPL35 | 0.78322 | 3 | 0 | 3 |
| TRAPPC6B | C2orf76 | 0.780317 | 3 | 0 | 3 |
| TRAPPC6B | LZIC | 0.779985 | 3 | 0 | 3 |
| TRAPPC6B | RAB18 | 0.779534 | 3 | 0 | 3 |
| TRAPPC6B | JAK1 | 0.779097 | 3 | 0 | 3 |
| TRAPPC6B | PFKFB2 | 0.776327 | 3 | 0 | 3 |
| TRAPPC6B | LYSMD3 | 0.768919 | 3 | 0 | 3 |
| TRAPPC6B | SPCS2 | 0.766135 | 3 | 0 | 3 |
| TRAPPC6B | BCS1L | 0.765549 | 3 | 0 | 3 |
| TRAPPC6B | TMEM126A | 0.765141 | 3 | 0 | 3 |
| TRAPPC6B | RNF144B | 0.76491 | 4 | 0 | 4 |
| TRAPPC6B | AGGF1 | 0.763899 | 3 | 0 | 3 |
For details and further investigation, click here
