| Full name: DExH-box helicase 34 | Alias Symbol: KIAA0134 | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 9704 | HGNC ID: HGNC:16719 | Ensembl Gene: ENSG00000134815 | OMIM ID: 615475 |
| Drug and gene relationship at DGIdb | |||
Expression of DHX34:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DHX34 | 9704 | 214017_s_at | 1.0149 | 0.1162 | |
| GSE20347 | DHX34 | 9704 | 214017_s_at | 0.4456 | 0.0001 | |
| GSE23400 | DHX34 | 9704 | 214017_s_at | 0.2734 | 0.0000 | |
| GSE26886 | DHX34 | 9704 | 214017_s_at | 0.5073 | 0.0005 | |
| GSE29001 | DHX34 | 9704 | 214017_s_at | 0.2075 | 0.2757 | |
| GSE38129 | DHX34 | 9704 | 214017_s_at | 0.5455 | 0.0000 | |
| GSE45670 | DHX34 | 9704 | 214017_s_at | 0.2657 | 0.0194 | |
| GSE53622 | DHX34 | 9704 | 63703 | 0.3413 | 0.0000 | |
| GSE53624 | DHX34 | 9704 | 63703 | 0.6998 | 0.0000 | |
| GSE63941 | DHX34 | 9704 | 214017_s_at | 0.7454 | 0.0301 | |
| GSE77861 | DHX34 | 9704 | 214017_s_at | 0.2415 | 0.0216 | |
| GSE97050 | DHX34 | 9704 | A_33_P3315856 | 0.2013 | 0.2919 | |
| SRP007169 | DHX34 | 9704 | RNAseq | 0.9540 | 0.0430 | |
| SRP008496 | DHX34 | 9704 | RNAseq | 0.7006 | 0.0309 | |
| SRP064894 | DHX34 | 9704 | RNAseq | 0.9367 | 0.0003 | |
| SRP133303 | DHX34 | 9704 | RNAseq | 0.6433 | 0.0022 | |
| SRP159526 | DHX34 | 9704 | RNAseq | 1.0277 | 0.0190 | |
| SRP193095 | DHX34 | 9704 | RNAseq | 0.7896 | 0.0000 | |
| SRP219564 | DHX34 | 9704 | RNAseq | 0.6759 | 0.1385 | |
| TCGA | DHX34 | 9704 | RNAseq | 0.2315 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DHX34 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DHX34:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DHX34 | 9704 | 4 | 4 | 22 | |
| GSE20123 | DHX34 | 9704 | 4 | 3 | 23 | |
| GSE43470 | DHX34 | 9704 | 3 | 10 | 30 | |
| GSE46452 | DHX34 | 9704 | 45 | 1 | 13 | |
| GSE47630 | DHX34 | 9704 | 8 | 7 | 25 | |
| GSE54993 | DHX34 | 9704 | 17 | 4 | 49 | |
| GSE54994 | DHX34 | 9704 | 4 | 14 | 35 | |
| GSE60625 | DHX34 | 9704 | 9 | 0 | 2 | |
| GSE74703 | DHX34 | 9704 | 3 | 7 | 26 | |
| GSE74704 | DHX34 | 9704 | 4 | 1 | 15 | |
| TCGA | DHX34 | 9704 | 14 | 18 | 64 |
Total number of gains: 115; Total number of losses: 69; Total Number of normals: 304.
Somatic mutations of DHX34:
Generating mutation plots.
Highly correlated genes for DHX34:
Showing top 20/522 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DHX34 | CPAMD8 | 0.816674 | 3 | 0 | 3 |
| DHX34 | TIGD7 | 0.774605 | 3 | 0 | 3 |
| DHX34 | ARHGAP21 | 0.737617 | 3 | 0 | 3 |
| DHX34 | STK32C | 0.72563 | 4 | 0 | 4 |
| DHX34 | ZNF524 | 0.715704 | 3 | 0 | 3 |
| DHX34 | CEMP1 | 0.704473 | 4 | 0 | 3 |
| DHX34 | ZDHHC23 | 0.703204 | 4 | 0 | 3 |
| DHX34 | FBRSL1 | 0.698143 | 6 | 0 | 5 |
| DHX34 | KIF21B | 0.697653 | 3 | 0 | 3 |
| DHX34 | TIGD5 | 0.693742 | 6 | 0 | 6 |
| DHX34 | POLL | 0.693564 | 3 | 0 | 3 |
| DHX34 | SOX30 | 0.68929 | 3 | 0 | 3 |
| DHX34 | ING5 | 0.68883 | 3 | 0 | 3 |
| DHX34 | FPR1 | 0.685374 | 3 | 0 | 3 |
| DHX34 | HOXC9 | 0.680862 | 5 | 0 | 5 |
| DHX34 | DNLZ | 0.675983 | 4 | 0 | 3 |
| DHX34 | SLC6A3 | 0.674132 | 4 | 0 | 3 |
| DHX34 | CYP11B1 | 0.670708 | 4 | 0 | 3 |
| DHX34 | TAF5L | 0.668679 | 7 | 0 | 6 |
| DHX34 | TMEM120B | 0.665506 | 5 | 0 | 4 |
For details and further investigation, click here
