| Full name: TATA-box binding protein associated factor 5 like | Alias Symbol: PAF65B | ||
| Type: protein-coding gene | Cytoband: 1q42.13 | ||
| Entrez ID: 27097 | HGNC ID: HGNC:17304 | Ensembl Gene: ENSG00000135801 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TAF5L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAF5L | 27097 | 213654_at | 0.6013 | 0.0431 | |
| GSE20347 | TAF5L | 27097 | 213654_at | 0.3798 | 0.0000 | |
| GSE23400 | TAF5L | 27097 | 213654_at | 0.1599 | 0.0000 | |
| GSE26886 | TAF5L | 27097 | 213654_at | 0.4352 | 0.0053 | |
| GSE29001 | TAF5L | 27097 | 213654_at | 0.2860 | 0.0718 | |
| GSE38129 | TAF5L | 27097 | 213654_at | 0.3654 | 0.0000 | |
| GSE45670 | TAF5L | 27097 | 213654_at | 0.2903 | 0.0045 | |
| GSE53622 | TAF5L | 27097 | 152615 | -0.2332 | 0.0137 | |
| GSE53624 | TAF5L | 27097 | 152615 | -0.1410 | 0.1836 | |
| GSE63941 | TAF5L | 27097 | 213654_at | 1.0141 | 0.0005 | |
| GSE77861 | TAF5L | 27097 | 213654_at | 0.3376 | 0.0051 | |
| GSE97050 | TAF5L | 27097 | A_23_P35309 | 0.1387 | 0.5086 | |
| SRP007169 | TAF5L | 27097 | RNAseq | 0.3687 | 0.3543 | |
| SRP008496 | TAF5L | 27097 | RNAseq | 0.5095 | 0.0691 | |
| SRP064894 | TAF5L | 27097 | RNAseq | 0.1714 | 0.2596 | |
| SRP133303 | TAF5L | 27097 | RNAseq | 0.4728 | 0.0012 | |
| SRP159526 | TAF5L | 27097 | RNAseq | 0.4374 | 0.2359 | |
| SRP193095 | TAF5L | 27097 | RNAseq | 0.3164 | 0.0000 | |
| SRP219564 | TAF5L | 27097 | RNAseq | 0.1832 | 0.5137 | |
| TCGA | TAF5L | 27097 | RNAseq | 0.0637 | 0.2295 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TAF5L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAF5L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAF5L | 27097 | 11 | 0 | 19 | |
| GSE20123 | TAF5L | 27097 | 11 | 0 | 19 | |
| GSE43470 | TAF5L | 27097 | 8 | 1 | 34 | |
| GSE46452 | TAF5L | 27097 | 4 | 2 | 53 | |
| GSE47630 | TAF5L | 27097 | 15 | 0 | 25 | |
| GSE54993 | TAF5L | 27097 | 0 | 6 | 64 | |
| GSE54994 | TAF5L | 27097 | 17 | 0 | 36 | |
| GSE60625 | TAF5L | 27097 | 0 | 0 | 11 | |
| GSE74703 | TAF5L | 27097 | 8 | 1 | 27 | |
| GSE74704 | TAF5L | 27097 | 5 | 0 | 15 | |
| TCGA | TAF5L | 27097 | 45 | 3 | 48 |
Total number of gains: 124; Total number of losses: 13; Total Number of normals: 351.
Somatic mutations of TAF5L:
Generating mutation plots.
Highly correlated genes for TAF5L:
Showing top 20/433 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAF5L | TMEM120B | 0.819568 | 3 | 0 | 3 |
| TAF5L | ZDHHC8 | 0.819421 | 3 | 0 | 3 |
| TAF5L | PXYLP1 | 0.789423 | 3 | 0 | 3 |
| TAF5L | PYGO2 | 0.770052 | 4 | 0 | 4 |
| TAF5L | DOHH | 0.761407 | 3 | 0 | 3 |
| TAF5L | ZNF678 | 0.754554 | 5 | 0 | 5 |
| TAF5L | PLEKHG4 | 0.740175 | 3 | 0 | 3 |
| TAF5L | CDCA5 | 0.73639 | 5 | 0 | 5 |
| TAF5L | HAUS8 | 0.728693 | 5 | 0 | 5 |
| TAF5L | STK32C | 0.727151 | 3 | 0 | 3 |
| TAF5L | RAB3IL1 | 0.72098 | 3 | 0 | 3 |
| TAF5L | SOGA1 | 0.718339 | 4 | 0 | 3 |
| TAF5L | CCSAP | 0.713575 | 4 | 0 | 4 |
| TAF5L | PHF12 | 0.711366 | 4 | 0 | 3 |
| TAF5L | TOR3A | 0.702335 | 7 | 0 | 6 |
| TAF5L | HOXC13 | 0.701711 | 4 | 0 | 3 |
| TAF5L | ODF2 | 0.697982 | 5 | 0 | 4 |
| TAF5L | ADAP1 | 0.697055 | 3 | 0 | 3 |
| TAF5L | ZNF687 | 0.696425 | 4 | 0 | 3 |
| TAF5L | BEND3 | 0.695974 | 6 | 0 | 6 |
For details and further investigation, click here
