| Full name: kinesin family member 21B | Alias Symbol: DKFZP434J212|KIAA0449 | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 23046 | HGNC ID: HGNC:29442 | Ensembl Gene: ENSG00000116852 | OMIM ID: 608322 |
| Drug and gene relationship at DGIdb | |||
Expression of KIF21B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIF21B | 23046 | 204411_at | 0.5684 | 0.0686 | |
| GSE20347 | KIF21B | 23046 | 204411_at | 0.0024 | 0.9845 | |
| GSE23400 | KIF21B | 23046 | 204411_at | -0.0427 | 0.3454 | |
| GSE26886 | KIF21B | 23046 | 204411_at | 0.2912 | 0.1364 | |
| GSE29001 | KIF21B | 23046 | 204411_at | 0.0630 | 0.7979 | |
| GSE38129 | KIF21B | 23046 | 204411_at | -0.1401 | 0.1773 | |
| GSE45670 | KIF21B | 23046 | 204411_at | 0.2732 | 0.1320 | |
| GSE53622 | KIF21B | 23046 | 63369 | 0.2792 | 0.0000 | |
| GSE53624 | KIF21B | 23046 | 63369 | 0.3466 | 0.0022 | |
| GSE63941 | KIF21B | 23046 | 204411_at | 0.7914 | 0.1084 | |
| GSE77861 | KIF21B | 23046 | 204411_at | -0.0703 | 0.6336 | |
| GSE97050 | KIF21B | 23046 | A_33_P3221665 | 0.6126 | 0.1399 | |
| SRP007169 | KIF21B | 23046 | RNAseq | 1.3134 | 0.1352 | |
| SRP064894 | KIF21B | 23046 | RNAseq | 0.7610 | 0.0109 | |
| SRP133303 | KIF21B | 23046 | RNAseq | 0.0989 | 0.6715 | |
| SRP159526 | KIF21B | 23046 | RNAseq | -0.1828 | 0.7360 | |
| SRP193095 | KIF21B | 23046 | RNAseq | 0.7982 | 0.0099 | |
| SRP219564 | KIF21B | 23046 | RNAseq | 1.1041 | 0.0201 | |
| TCGA | KIF21B | 23046 | RNAseq | -0.0580 | 0.6686 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by KIF21B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIF21B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIF21B | 23046 | 11 | 0 | 19 | |
| GSE20123 | KIF21B | 23046 | 11 | 0 | 19 | |
| GSE43470 | KIF21B | 23046 | 6 | 0 | 37 | |
| GSE46452 | KIF21B | 23046 | 3 | 1 | 55 | |
| GSE47630 | KIF21B | 23046 | 14 | 0 | 26 | |
| GSE54993 | KIF21B | 23046 | 0 | 6 | 64 | |
| GSE54994 | KIF21B | 23046 | 15 | 0 | 38 | |
| GSE60625 | KIF21B | 23046 | 0 | 0 | 11 | |
| GSE74703 | KIF21B | 23046 | 6 | 0 | 30 | |
| GSE74704 | KIF21B | 23046 | 5 | 0 | 15 | |
| TCGA | KIF21B | 23046 | 43 | 4 | 49 |
Total number of gains: 114; Total number of losses: 11; Total Number of normals: 363.
Somatic mutations of KIF21B:
Generating mutation plots.
Highly correlated genes for KIF21B:
Showing top 20/442 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIF21B | PTK2B | 0.804683 | 4 | 0 | 4 |
| KIF21B | IL1F10 | 0.761136 | 3 | 0 | 3 |
| KIF21B | LHX9 | 0.75656 | 3 | 0 | 3 |
| KIF21B | FTHL17 | 0.718812 | 3 | 0 | 3 |
| KIF21B | KRTAP13-1 | 0.717209 | 3 | 0 | 3 |
| KIF21B | SLC39A5 | 0.714578 | 3 | 0 | 3 |
| KIF21B | RECQL4 | 0.708151 | 3 | 0 | 3 |
| KIF21B | DHX34 | 0.697653 | 3 | 0 | 3 |
| KIF21B | ARL9 | 0.691657 | 3 | 0 | 3 |
| KIF21B | ATG2A | 0.691464 | 3 | 0 | 3 |
| KIF21B | ZNF497 | 0.689605 | 3 | 0 | 3 |
| KIF21B | ZDHHC8 | 0.677894 | 3 | 0 | 3 |
| KIF21B | KIR3DL3 | 0.67709 | 7 | 0 | 6 |
| KIF21B | KCTD19 | 0.677038 | 3 | 0 | 3 |
| KIF21B | KLHDC4 | 0.671939 | 4 | 0 | 4 |
| KIF21B | MATN1 | 0.667839 | 4 | 0 | 3 |
| KIF21B | USP49 | 0.666929 | 4 | 0 | 3 |
| KIF21B | ZNF205 | 0.666367 | 4 | 0 | 3 |
| KIF21B | TUSC1 | 0.6658 | 3 | 0 | 3 |
| KIF21B | FBXL18 | 0.662618 | 3 | 0 | 3 |
For details and further investigation, click here
