| Full name: SRY-box transcription factor 30 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q33.3 | ||
| Entrez ID: 11063 | HGNC ID: HGNC:30635 | Ensembl Gene: ENSG00000039600 | OMIM ID: 606698 |
| Drug and gene relationship at DGIdb | |||
Expression of SOX30:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SOX30 | 11063 | 207678_s_at | 0.5141 | 0.2189 | |
| GSE20347 | SOX30 | 11063 | 207678_s_at | 0.0679 | 0.1594 | |
| GSE23400 | SOX30 | 11063 | 207678_s_at | 0.0446 | 0.0755 | |
| GSE29001 | SOX30 | 11063 | 207678_s_at | 0.4266 | 0.0075 | |
| GSE38129 | SOX30 | 11063 | 207678_s_at | 0.1978 | 0.0890 | |
| GSE53622 | SOX30 | 11063 | 10520 | 0.1831 | 0.1853 | |
| GSE53624 | SOX30 | 11063 | 10520 | 0.5945 | 0.0000 | |
| GSE63941 | SOX30 | 11063 | 207678_s_at | 0.3226 | 0.1868 | |
| GSE97050 | SOX30 | 11063 | A_33_P3260563 | 0.0158 | 0.9628 | |
| SRP133303 | SOX30 | 11063 | RNAseq | 1.6491 | 0.0041 | |
| TCGA | SOX30 | 11063 | RNAseq | 1.4311 | 0.0007 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SOX30 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SOX30:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SOX30 | 11063 | 0 | 11 | 19 | |
| GSE20123 | SOX30 | 11063 | 0 | 11 | 19 | |
| GSE43470 | SOX30 | 11063 | 2 | 11 | 30 | |
| GSE46452 | SOX30 | 11063 | 0 | 27 | 32 | |
| GSE47630 | SOX30 | 11063 | 0 | 20 | 20 | |
| GSE54993 | SOX30 | 11063 | 9 | 1 | 60 | |
| GSE54994 | SOX30 | 11063 | 1 | 16 | 36 | |
| GSE60625 | SOX30 | 11063 | 0 | 0 | 11 | |
| GSE74703 | SOX30 | 11063 | 2 | 8 | 26 | |
| GSE74704 | SOX30 | 11063 | 0 | 6 | 14 | |
| TCGA | SOX30 | 11063 | 5 | 36 | 55 |
Total number of gains: 19; Total number of losses: 147; Total Number of normals: 322.
Somatic mutations of SOX30:
Generating mutation plots.
Highly correlated genes for SOX30:
Showing top 20/77 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SOX30 | NRF1 | 0.779066 | 3 | 0 | 3 |
| SOX30 | OTUD4 | 0.776561 | 3 | 0 | 3 |
| SOX30 | RBM28 | 0.773948 | 3 | 0 | 3 |
| SOX30 | YEATS2 | 0.773839 | 3 | 0 | 3 |
| SOX30 | ARL8A | 0.739798 | 3 | 0 | 3 |
| SOX30 | TAF4 | 0.738128 | 3 | 0 | 3 |
| SOX30 | ZNF639 | 0.733508 | 3 | 0 | 3 |
| SOX30 | TAF5 | 0.727565 | 3 | 0 | 3 |
| SOX30 | CDK16 | 0.702237 | 3 | 0 | 3 |
| SOX30 | DHX34 | 0.68929 | 3 | 0 | 3 |
| SOX30 | APTX | 0.685508 | 3 | 0 | 3 |
| SOX30 | SPTA1 | 0.677109 | 3 | 0 | 3 |
| SOX30 | ZBTB24 | 0.670112 | 3 | 0 | 3 |
| SOX30 | APBA2 | 0.66782 | 4 | 0 | 4 |
| SOX30 | RHBDL1 | 0.664149 | 3 | 0 | 3 |
| SOX30 | NRG4 | 0.648079 | 3 | 0 | 3 |
| SOX30 | TMEM39A | 0.645233 | 3 | 0 | 3 |
| SOX30 | ZNF157 | 0.641356 | 4 | 0 | 4 |
| SOX30 | GYPE | 0.636679 | 4 | 0 | 4 |
| SOX30 | TPH1 | 0.634214 | 4 | 0 | 4 |
For details and further investigation, click here
