| Full name: delta like non-canonical Notch ligand 1 | Alias Symbol: FA1|pG2|Pref-1|ZOG|Delta1 | ||
| Type: protein-coding gene | Cytoband: 14q32.2 | ||
| Entrez ID: 8788 | HGNC ID: HGNC:2907 | Ensembl Gene: ENSG00000185559 | OMIM ID: 176290 |
| Drug and gene relationship at DGIdb | |||
Expression of DLK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DLK1 | 8788 | 235600_at | 0.0153 | 0.9673 | |
| GSE20347 | DLK1 | 8788 | 209560_s_at | 0.2868 | 0.4918 | |
| GSE23400 | DLK1 | 8788 | 209560_s_at | -0.2152 | 0.0000 | |
| GSE26886 | DLK1 | 8788 | 235600_at | 0.2687 | 0.0408 | |
| GSE29001 | DLK1 | 8788 | 209560_s_at | 0.3980 | 0.5307 | |
| GSE38129 | DLK1 | 8788 | 209560_s_at | 0.2557 | 0.6903 | |
| GSE45670 | DLK1 | 8788 | 235600_at | 0.1427 | 0.1925 | |
| GSE53622 | DLK1 | 8788 | 71773 | 0.0330 | 0.7795 | |
| GSE53624 | DLK1 | 8788 | 71773 | -0.2546 | 0.0060 | |
| GSE63941 | DLK1 | 8788 | 235600_at | 0.1299 | 0.3901 | |
| GSE77861 | DLK1 | 8788 | 235600_at | -0.0336 | 0.7852 | |
| GSE97050 | DLK1 | 8788 | A_33_P3217559 | -0.0008 | 0.9977 | |
| TCGA | DLK1 | 8788 | RNAseq | -1.6069 | 0.2406 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DLK1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DLK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DLK1 | 8788 | 9 | 5 | 16 | |
| GSE20123 | DLK1 | 8788 | 9 | 4 | 17 | |
| GSE43470 | DLK1 | 8788 | 7 | 4 | 32 | |
| GSE46452 | DLK1 | 8788 | 18 | 3 | 38 | |
| GSE47630 | DLK1 | 8788 | 11 | 8 | 21 | |
| GSE54993 | DLK1 | 8788 | 3 | 8 | 59 | |
| GSE54994 | DLK1 | 8788 | 21 | 4 | 28 | |
| GSE60625 | DLK1 | 8788 | 0 | 2 | 9 | |
| GSE74703 | DLK1 | 8788 | 6 | 3 | 27 | |
| GSE74704 | DLK1 | 8788 | 5 | 3 | 12 | |
| TCGA | DLK1 | 8788 | 32 | 17 | 47 |
Total number of gains: 121; Total number of losses: 61; Total Number of normals: 306.
Somatic mutations of DLK1:
Generating mutation plots.
Highly correlated genes for DLK1:
Showing top 20/396 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DLK1 | TMEM221 | 0.816346 | 3 | 0 | 3 |
| DLK1 | PCSK1N | 0.773863 | 3 | 0 | 3 |
| DLK1 | SLC22A1 | 0.772839 | 3 | 0 | 3 |
| DLK1 | FBLN7 | 0.744172 | 4 | 0 | 4 |
| DLK1 | ALDH8A1 | 0.724334 | 3 | 0 | 3 |
| DLK1 | EBF4 | 0.721851 | 4 | 0 | 4 |
| DLK1 | CCNJL | 0.719743 | 3 | 0 | 3 |
| DLK1 | SPACA3 | 0.717802 | 4 | 0 | 3 |
| DLK1 | PALM3 | 0.715684 | 3 | 0 | 3 |
| DLK1 | FAM181A | 0.710528 | 4 | 0 | 3 |
| DLK1 | MAGEC2 | 0.703928 | 3 | 0 | 3 |
| DLK1 | DPEP1 | 0.70097 | 3 | 0 | 3 |
| DLK1 | HIF3A | 0.6964 | 3 | 0 | 3 |
| DLK1 | FERD3L | 0.695834 | 3 | 0 | 3 |
| DLK1 | CDHR5 | 0.692989 | 4 | 0 | 4 |
| DLK1 | FAM178B | 0.691486 | 4 | 0 | 3 |
| DLK1 | ABCC8 | 0.690969 | 3 | 0 | 3 |
| DLK1 | THEG | 0.684539 | 3 | 0 | 3 |
| DLK1 | CLSTN3 | 0.680491 | 4 | 0 | 4 |
| DLK1 | RPP25 | 0.679558 | 3 | 0 | 3 |
For details and further investigation, click here
