| Full name: proprotein convertase subtilisin/kexin type 1 inhibitor | Alias Symbol: SAAS|SgVIII|SCG8|proSAAS|PEN|BigLEN | ||
| Type: protein-coding gene | Cytoband: Xp11.23 | ||
| Entrez ID: 27344 | HGNC ID: HGNC:17301 | Ensembl Gene: ENSG00000102109 | OMIM ID: 300399 |
| Drug and gene relationship at DGIdb | |||
Expression of PCSK1N:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCSK1N | 27344 | 218952_at | 0.3001 | 0.7140 | |
| GSE20347 | PCSK1N | 27344 | 218952_at | 0.2223 | 0.0324 | |
| GSE23400 | PCSK1N | 27344 | 218952_at | 0.1181 | 0.0878 | |
| GSE26886 | PCSK1N | 27344 | 218952_at | 0.4619 | 0.0015 | |
| GSE29001 | PCSK1N | 27344 | 218952_at | 0.1359 | 0.5608 | |
| GSE38129 | PCSK1N | 27344 | 218952_at | 0.2225 | 0.1470 | |
| GSE45670 | PCSK1N | 27344 | 218952_at | 0.1511 | 0.3772 | |
| GSE53622 | PCSK1N | 27344 | 93600 | 0.1484 | 0.1006 | |
| GSE53624 | PCSK1N | 27344 | 93600 | 0.2846 | 0.0003 | |
| GSE63941 | PCSK1N | 27344 | 218952_at | 0.8837 | 0.0720 | |
| GSE77861 | PCSK1N | 27344 | 218952_at | 0.2178 | 0.3146 | |
| GSE97050 | PCSK1N | 27344 | A_24_P14731 | -0.0084 | 0.9806 | |
| SRP159526 | PCSK1N | 27344 | RNAseq | 3.1174 | 0.0054 | |
| SRP219564 | PCSK1N | 27344 | RNAseq | 2.7460 | 0.0173 | |
| TCGA | PCSK1N | 27344 | RNAseq | -0.3454 | 0.3773 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by PCSK1N expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PCSK1N:
No record found for this gene.
Somatic mutations of PCSK1N:
Generating mutation plots.
Highly correlated genes for PCSK1N:
Showing top 20/346 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCSK1N | ZNF329 | 0.777812 | 3 | 0 | 3 |
| PCSK1N | DLK1 | 0.773863 | 3 | 0 | 3 |
| PCSK1N | SYT3 | 0.753913 | 3 | 0 | 3 |
| PCSK1N | DCDC1 | 0.753604 | 3 | 0 | 3 |
| PCSK1N | GGTLC1 | 0.749357 | 3 | 0 | 3 |
| PCSK1N | MRGPRG | 0.743429 | 3 | 0 | 3 |
| PCSK1N | C19orf81 | 0.742214 | 3 | 0 | 3 |
| PCSK1N | C2CD4D | 0.738583 | 3 | 0 | 3 |
| PCSK1N | ANXA10 | 0.738254 | 3 | 0 | 3 |
| PCSK1N | ASMTL | 0.734675 | 4 | 0 | 4 |
| PCSK1N | REM2 | 0.726319 | 4 | 0 | 3 |
| PCSK1N | C1QL2 | 0.725773 | 3 | 0 | 3 |
| PCSK1N | BMF | 0.718149 | 3 | 0 | 3 |
| PCSK1N | AIFM3 | 0.715792 | 4 | 0 | 4 |
| PCSK1N | EYS | 0.713872 | 3 | 0 | 3 |
| PCSK1N | LIME1 | 0.71249 | 4 | 0 | 3 |
| PCSK1N | CFC1 | 0.711758 | 3 | 0 | 3 |
| PCSK1N | C19orf71 | 0.710766 | 3 | 0 | 3 |
| PCSK1N | KIRREL2 | 0.710131 | 4 | 0 | 3 |
| PCSK1N | LYG1 | 0.709305 | 4 | 0 | 3 |
For details and further investigation, click here
