| Full name: dentin matrix acidic phosphoprotein 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q22.1 | ||
| Entrez ID: 1758 | HGNC ID: HGNC:2932 | Ensembl Gene: ENSG00000152592 | OMIM ID: 600980 |
| Drug and gene relationship at DGIdb | |||
Expression of DMP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DMP1 | 1758 | 208175_s_at | 0.3622 | 0.1630 | |
| GSE20347 | DMP1 | 1758 | 208175_s_at | 0.1839 | 0.0058 | |
| GSE23400 | DMP1 | 1758 | 208175_s_at | 0.0537 | 0.0069 | |
| GSE26886 | DMP1 | 1758 | 217067_s_at | -0.0230 | 0.8643 | |
| GSE29001 | DMP1 | 1758 | 208175_s_at | 0.1141 | 0.3321 | |
| GSE38129 | DMP1 | 1758 | 208175_s_at | 0.0741 | 0.1301 | |
| GSE45670 | DMP1 | 1758 | 217067_s_at | 0.0978 | 0.1673 | |
| GSE53622 | DMP1 | 1758 | 117113 | 1.3679 | 0.0000 | |
| GSE53624 | DMP1 | 1758 | 117113 | 1.2239 | 0.0000 | |
| GSE63941 | DMP1 | 1758 | 208175_s_at | 0.3318 | 0.2883 | |
| GSE77861 | DMP1 | 1758 | 217067_s_at | -0.0961 | 0.4498 | |
| GSE97050 | DMP1 | 1758 | A_23_P133153 | 0.4663 | 0.2331 | |
| SRP133303 | DMP1 | 1758 | RNAseq | 3.4883 | 0.0006 | |
| TCGA | DMP1 | 1758 | RNAseq | 4.0274 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by DMP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DMP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DMP1 | 1758 | 3 | 12 | 15 | |
| GSE20123 | DMP1 | 1758 | 3 | 12 | 15 | |
| GSE43470 | DMP1 | 1758 | 0 | 13 | 30 | |
| GSE46452 | DMP1 | 1758 | 2 | 35 | 22 | |
| GSE47630 | DMP1 | 1758 | 0 | 20 | 20 | |
| GSE54993 | DMP1 | 1758 | 8 | 0 | 62 | |
| GSE54994 | DMP1 | 1758 | 1 | 9 | 43 | |
| GSE60625 | DMP1 | 1758 | 0 | 0 | 11 | |
| GSE74703 | DMP1 | 1758 | 0 | 11 | 25 | |
| GSE74704 | DMP1 | 1758 | 2 | 7 | 11 | |
| TCGA | DMP1 | 1758 | 12 | 36 | 48 |
Total number of gains: 31; Total number of losses: 155; Total Number of normals: 302.
Somatic mutations of DMP1:
Generating mutation plots.
Highly correlated genes for DMP1:
Showing top 20/231 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DMP1 | SLC35F3 | 0.761643 | 3 | 0 | 3 |
| DMP1 | ZNF221 | 0.752542 | 3 | 0 | 3 |
| DMP1 | NCAN | 0.745391 | 3 | 0 | 3 |
| DMP1 | LMAN1L | 0.735078 | 3 | 0 | 3 |
| DMP1 | GPRIN1 | 0.73143 | 4 | 0 | 4 |
| DMP1 | MIIP | 0.72875 | 3 | 0 | 3 |
| DMP1 | NPM2 | 0.701869 | 3 | 0 | 3 |
| DMP1 | CLCNKB | 0.700552 | 3 | 0 | 3 |
| DMP1 | LILRA3 | 0.700086 | 3 | 0 | 3 |
| DMP1 | YJEFN3 | 0.698911 | 3 | 0 | 3 |
| DMP1 | PRKRIP1 | 0.694996 | 3 | 0 | 3 |
| DMP1 | ACSF3 | 0.694816 | 3 | 0 | 3 |
| DMP1 | TMEM9 | 0.689929 | 3 | 0 | 3 |
| DMP1 | AGAP2 | 0.688221 | 4 | 0 | 4 |
| DMP1 | ACVR2B | 0.687726 | 3 | 0 | 3 |
| DMP1 | ZNF157 | 0.680945 | 4 | 0 | 3 |
| DMP1 | BOLL | 0.679673 | 4 | 0 | 3 |
| DMP1 | MFSD10 | 0.678881 | 4 | 0 | 4 |
| DMP1 | C1QTNF6 | 0.67666 | 4 | 0 | 4 |
| DMP1 | HDAC8 | 0.675115 | 3 | 0 | 3 |
For details and further investigation, click here
