| Full name: zinc finger protein 221 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.31 | ||
| Entrez ID: 7638 | HGNC ID: HGNC:13014 | Ensembl Gene: ENSG00000159905 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZNF221:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF221 | 7638 | 233848_x_at | 0.0312 | 0.9089 | |
| GSE20347 | ZNF221 | 7638 | 220847_x_at | 0.0222 | 0.7931 | |
| GSE23400 | ZNF221 | 7638 | 220847_x_at | -0.0523 | 0.0885 | |
| GSE26886 | ZNF221 | 7638 | 233848_x_at | -0.0364 | 0.7304 | |
| GSE29001 | ZNF221 | 7638 | 220847_x_at | -0.0163 | 0.9252 | |
| GSE38129 | ZNF221 | 7638 | 220847_x_at | -0.1556 | 0.0085 | |
| GSE45670 | ZNF221 | 7638 | 220847_x_at | -0.0262 | 0.7651 | |
| GSE63941 | ZNF221 | 7638 | 233848_x_at | -0.1317 | 0.4244 | |
| GSE77861 | ZNF221 | 7638 | 233848_x_at | -0.0239 | 0.8393 | |
| GSE97050 | ZNF221 | 7638 | A_23_P90320 | -0.1336 | 0.6123 | |
| SRP133303 | ZNF221 | 7638 | RNAseq | -0.0531 | 0.7848 | |
| SRP193095 | ZNF221 | 7638 | RNAseq | 0.0404 | 0.8192 | |
| SRP219564 | ZNF221 | 7638 | RNAseq | -0.5807 | 0.1726 | |
| TCGA | ZNF221 | 7638 | RNAseq | -0.6102 | 0.0113 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF221 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ZNF221:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF221 | 7638 | 6 | 5 | 19 | |
| GSE20123 | ZNF221 | 7638 | 5 | 4 | 21 | |
| GSE43470 | ZNF221 | 7638 | 4 | 11 | 28 | |
| GSE46452 | ZNF221 | 7638 | 45 | 1 | 13 | |
| GSE47630 | ZNF221 | 7638 | 8 | 6 | 26 | |
| GSE54993 | ZNF221 | 7638 | 17 | 4 | 49 | |
| GSE54994 | ZNF221 | 7638 | 6 | 12 | 35 | |
| GSE60625 | ZNF221 | 7638 | 9 | 0 | 2 | |
| GSE74703 | ZNF221 | 7638 | 4 | 7 | 25 | |
| GSE74704 | ZNF221 | 7638 | 4 | 2 | 14 | |
| TCGA | ZNF221 | 7638 | 14 | 16 | 66 |
Total number of gains: 122; Total number of losses: 68; Total Number of normals: 298.
Somatic mutations of ZNF221:
Generating mutation plots.
Highly correlated genes for ZNF221:
Showing top 20/470 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF221 | DMP1 | 0.752542 | 3 | 0 | 3 |
| ZNF221 | NPPA | 0.747412 | 4 | 0 | 4 |
| ZNF221 | C8G | 0.735746 | 3 | 0 | 3 |
| ZNF221 | LY6H | 0.729126 | 3 | 0 | 3 |
| ZNF221 | WAS | 0.720978 | 3 | 0 | 3 |
| ZNF221 | WDR83 | 0.708402 | 3 | 0 | 3 |
| ZNF221 | CEMP1 | 0.702501 | 5 | 0 | 4 |
| ZNF221 | RRP1 | 0.701169 | 3 | 0 | 3 |
| ZNF221 | YBX2 | 0.697778 | 3 | 0 | 3 |
| ZNF221 | TRPM3 | 0.694835 | 5 | 0 | 4 |
| ZNF221 | USP27X | 0.693699 | 4 | 0 | 3 |
| ZNF221 | DMC1 | 0.689591 | 3 | 0 | 3 |
| ZNF221 | RUNDC3A | 0.689192 | 4 | 0 | 4 |
| ZNF221 | ZNF81 | 0.688999 | 3 | 0 | 3 |
| ZNF221 | FSCN2 | 0.686267 | 3 | 0 | 3 |
| ZNF221 | ZMAT4 | 0.684259 | 3 | 0 | 3 |
| ZNF221 | PHF7 | 0.683162 | 6 | 0 | 6 |
| ZNF221 | GDPD5 | 0.683119 | 5 | 0 | 5 |
| ZNF221 | ADAM20 | 0.68126 | 3 | 0 | 3 |
| ZNF221 | RTEL1 | 0.680491 | 4 | 0 | 4 |
For details and further investigation, click here
