| Full name: histone deacetylase 8 | Alias Symbol: RPD3|KDAC8 | ||
| Type: protein-coding gene | Cytoband: Xq13.1 | ||
| Entrez ID: 55869 | HGNC ID: HGNC:13315 | Ensembl Gene: ENSG00000147099 | OMIM ID: 300269 |
| Drug and gene relationship at DGIdb | |||
Expression of HDAC8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HDAC8 | 55869 | 223345_at | 0.4579 | 0.1754 | |
| GSE26886 | HDAC8 | 55869 | 223909_s_at | 0.1649 | 0.1153 | |
| GSE45670 | HDAC8 | 55869 | 223345_at | 0.2606 | 0.1900 | |
| GSE53622 | HDAC8 | 55869 | 87485 | 0.1725 | 0.0071 | |
| GSE53624 | HDAC8 | 55869 | 26844 | 0.1585 | 0.0018 | |
| GSE63941 | HDAC8 | 55869 | 223345_at | 0.0177 | 0.9777 | |
| GSE77861 | HDAC8 | 55869 | 223345_at | -0.1639 | 0.1971 | |
| GSE97050 | HDAC8 | 55869 | A_24_P254965 | 0.2191 | 0.2830 | |
| SRP007169 | HDAC8 | 55869 | RNAseq | 0.0965 | 0.8618 | |
| SRP008496 | HDAC8 | 55869 | RNAseq | 0.1136 | 0.7495 | |
| SRP064894 | HDAC8 | 55869 | RNAseq | 0.4368 | 0.0033 | |
| SRP133303 | HDAC8 | 55869 | RNAseq | 0.4332 | 0.0362 | |
| SRP159526 | HDAC8 | 55869 | RNAseq | 0.6117 | 0.0608 | |
| SRP193095 | HDAC8 | 55869 | RNAseq | 0.1035 | 0.2970 | |
| SRP219564 | HDAC8 | 55869 | RNAseq | 0.0906 | 0.6989 | |
| TCGA | HDAC8 | 55869 | RNAseq | 0.0922 | 0.1372 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HDAC8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HDAC8:
No record found for this gene.
Somatic mutations of HDAC8:
Generating mutation plots.
Highly correlated genes for HDAC8:
Showing top 20/54 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HDAC8 | ADAMTS13 | 0.796123 | 3 | 0 | 3 |
| HDAC8 | ZNF341 | 0.746333 | 3 | 0 | 3 |
| HDAC8 | ABCA7 | 0.73656 | 3 | 0 | 3 |
| HDAC8 | HOTAIR | 0.720049 | 3 | 0 | 3 |
| HDAC8 | EFNA4 | 0.715257 | 3 | 0 | 3 |
| HDAC8 | GPRIN1 | 0.712686 | 3 | 0 | 3 |
| HDAC8 | PLEC | 0.710963 | 3 | 0 | 3 |
| HDAC8 | GNL1 | 0.700463 | 4 | 0 | 3 |
| HDAC8 | SCARF2 | 0.69746 | 3 | 0 | 3 |
| HDAC8 | DHX9 | 0.69524 | 3 | 0 | 3 |
| HDAC8 | MBD6 | 0.694501 | 3 | 0 | 3 |
| HDAC8 | BTBD8 | 0.692097 | 3 | 0 | 3 |
| HDAC8 | BCL6B | 0.686338 | 3 | 0 | 3 |
| HDAC8 | KIF26B | 0.684782 | 3 | 0 | 3 |
| HDAC8 | PKLR | 0.677738 | 4 | 0 | 3 |
| HDAC8 | FBXO15 | 0.677281 | 4 | 0 | 4 |
| HDAC8 | ZNF283 | 0.67633 | 3 | 0 | 3 |
| HDAC8 | DMP1 | 0.675115 | 3 | 0 | 3 |
| HDAC8 | HES7 | 0.672545 | 3 | 0 | 3 |
| HDAC8 | STEAP3 | 0.657994 | 3 | 0 | 3 |
For details and further investigation, click here
