| Full name: dynein axonemal heavy chain 1 | Alias Symbol: XLHSRF-1|DNAHC1|HDHC7|HL-11|HL11 | ||
| Type: protein-coding gene | Cytoband: 3p21.1 | ||
| Entrez ID: 25981 | HGNC ID: HGNC:2940 | Ensembl Gene: ENSG00000114841 | OMIM ID: 603332 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAH1 | 25981 | 1566775_at | -0.1240 | 0.6070 | |
| GSE26886 | DNAH1 | 25981 | 1566775_at | -0.1448 | 0.2685 | |
| GSE45670 | DNAH1 | 25981 | 1566775_at | 0.0676 | 0.5944 | |
| GSE53622 | DNAH1 | 25981 | 6699 | -0.6460 | 0.0000 | |
| GSE53624 | DNAH1 | 25981 | 6699 | -0.3276 | 0.0000 | |
| GSE63941 | DNAH1 | 25981 | 1566775_at | 0.2280 | 0.0968 | |
| GSE77861 | DNAH1 | 25981 | 228112_at | -0.0506 | 0.7497 | |
| GSE97050 | DNAH1 | 25981 | A_23_P18213 | 0.1117 | 0.5442 | |
| SRP007169 | DNAH1 | 25981 | RNAseq | -0.6009 | 0.3111 | |
| SRP064894 | DNAH1 | 25981 | RNAseq | -0.7116 | 0.0133 | |
| SRP133303 | DNAH1 | 25981 | RNAseq | -0.9549 | 0.0000 | |
| SRP159526 | DNAH1 | 25981 | RNAseq | -0.9729 | 0.0054 | |
| SRP193095 | DNAH1 | 25981 | RNAseq | -0.5398 | 0.0012 | |
| SRP219564 | DNAH1 | 25981 | RNAseq | -0.6140 | 0.0890 | |
| TCGA | DNAH1 | 25981 | RNAseq | -0.6425 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DNAH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAH1 | 25981 | 0 | 18 | 12 | |
| GSE20123 | DNAH1 | 25981 | 0 | 19 | 11 | |
| GSE43470 | DNAH1 | 25981 | 0 | 18 | 25 | |
| GSE46452 | DNAH1 | 25981 | 2 | 17 | 40 | |
| GSE47630 | DNAH1 | 25981 | 1 | 24 | 15 | |
| GSE54993 | DNAH1 | 25981 | 6 | 2 | 62 | |
| GSE54994 | DNAH1 | 25981 | 0 | 33 | 20 | |
| GSE60625 | DNAH1 | 25981 | 5 | 0 | 6 | |
| GSE74703 | DNAH1 | 25981 | 0 | 14 | 22 | |
| GSE74704 | DNAH1 | 25981 | 0 | 12 | 8 | |
| TCGA | DNAH1 | 25981 | 0 | 78 | 18 |
Total number of gains: 14; Total number of losses: 235; Total Number of normals: 239.
Somatic mutations of DNAH1:
Generating mutation plots.
Highly correlated genes for DNAH1:
Showing top 20/213 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAH1 | ARL2BP | 0.791255 | 3 | 0 | 3 |
| DNAH1 | OCM2 | 0.789001 | 3 | 0 | 3 |
| DNAH1 | TMEM167B | 0.782233 | 3 | 0 | 3 |
| DNAH1 | E2F4 | 0.774696 | 5 | 0 | 5 |
| DNAH1 | STOML2 | 0.771717 | 3 | 0 | 3 |
| DNAH1 | MPV17L | 0.750378 | 4 | 0 | 4 |
| DNAH1 | RNLS | 0.749135 | 3 | 0 | 3 |
| DNAH1 | TMEM107 | 0.741339 | 3 | 0 | 3 |
| DNAH1 | SURF4 | 0.737699 | 3 | 0 | 3 |
| DNAH1 | IRAK2 | 0.732735 | 3 | 0 | 3 |
| DNAH1 | ADAM11 | 0.725304 | 4 | 0 | 4 |
| DNAH1 | KCND1 | 0.714043 | 4 | 0 | 3 |
| DNAH1 | CNR1 | 0.708071 | 4 | 0 | 4 |
| DNAH1 | MRRF | 0.704922 | 3 | 0 | 3 |
| DNAH1 | STPG2 | 0.704513 | 3 | 0 | 3 |
| DNAH1 | JMJD1C | 0.699424 | 3 | 0 | 3 |
| DNAH1 | CCDC7 | 0.69906 | 3 | 0 | 3 |
| DNAH1 | DCXR | 0.694502 | 3 | 0 | 3 |
| DNAH1 | CCDC65 | 0.693883 | 4 | 0 | 3 |
| DNAH1 | SDHB | 0.691081 | 3 | 0 | 3 |
For details and further investigation, click here
