STOML2

 

Full name: stomatin like 2 Alias Symbol: SLP-2|HSPC108
Type: protein-coding gene Cytoband: 9p13.3
Entrez ID: 30968 HGNC ID: HGNC:14559 Ensembl Gene: ENSG00000165283 OMIM ID: 608292
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of STOML2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 STOML2 30968 215416_s_at -0.1498 0.8266
GSE20347 STOML2 30968 215416_s_at -0.0724 0.7532
GSE23400 STOML2 30968 215416_s_at 0.2665 0.0035
GSE26886 STOML2 30968 215416_s_at -0.7577 0.0009
GSE29001 STOML2 30968 215416_s_at 0.1803 0.6847
GSE38129 STOML2 30968 215416_s_at 0.1370 0.3967
GSE45670 STOML2 30968 215416_s_at 0.1083 0.5833
GSE53622 STOML2 30968 1316 0.1606 0.0283
GSE53624 STOML2 30968 1316 0.4287 0.0000
GSE63941 STOML2 30968 215416_s_at 1.3783 0.0007
GSE77861 STOML2 30968 215416_s_at -0.1110 0.7987
GSE97050 STOML2 30968 A_24_P338145 0.2559 0.3983
SRP007169 STOML2 30968 RNAseq -0.1298 0.7152
SRP008496 STOML2 30968 RNAseq 0.1814 0.5070
SRP064894 STOML2 30968 RNAseq 0.5340 0.0518
SRP133303 STOML2 30968 RNAseq 0.0148 0.9155
SRP159526 STOML2 30968 RNAseq -0.0396 0.8585
SRP193095 STOML2 30968 RNAseq -0.2457 0.0926
SRP219564 STOML2 30968 RNAseq 0.2394 0.5857
TCGA STOML2 30968 RNAseq 0.0735 0.2407

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by STOML2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of STOML2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 STOML2 30968 3 12 15
GSE20123 STOML2 30968 3 12 15
GSE43470 STOML2 30968 3 10 30
GSE46452 STOML2 30968 6 15 38
GSE47630 STOML2 30968 1 20 19
GSE54993 STOML2 30968 6 0 64
GSE54994 STOML2 30968 6 12 35
GSE60625 STOML2 30968 0 0 11
GSE74703 STOML2 30968 2 7 27
GSE74704 STOML2 30968 0 10 10
TCGA STOML2 30968 16 44 36

Total number of gains: 46; Total number of losses: 142; Total Number of normals: 300.  

 

Somatic mutations of STOML2:

 

Generating mutation plots.

 

Highly correlated genes for STOML2:

 

Showing top 20/581 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
STOML2AP3M10.815211303
STOML2CSTF20.801684303
STOML2DNAH10.771717303
STOML2PRKAB10.770913303
STOML2VPS250.761223303
STOML2SNX120.755475303
STOML2TNFAIP80.750825303
STOML2SPTLC20.748135303
STOML2OXNAD10.745502303
STOML2ATF10.740473404
STOML2DYRK20.735002303
STOML2BTBD70.730865303
STOML2MUL10.730206303
STOML2RAB180.727431303
STOML2CHMP4B0.72141303
STOML2TCEANC20.718429404
STOML2PIAS20.717378303
STOML2WDR200.717239303
STOML2RPP25L0.714761606
STOML2PITHD10.714648303

For details and further investigation, click here