| Full name: surfeit 4 | Alias Symbol: ERV29|FLJ22993|MGC102753 | ||
| Type: protein-coding gene | Cytoband: 9q34.2 | ||
| Entrez ID: 6836 | HGNC ID: HGNC:11476 | Ensembl Gene: ENSG00000148248 | OMIM ID: 185660 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SURF4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SURF4 | 6836 | 222978_at | 0.1110 | 0.8117 | |
| GSE26886 | SURF4 | 6836 | 222978_at | -0.5861 | 0.0119 | |
| GSE45670 | SURF4 | 6836 | 222978_at | 0.3089 | 0.0096 | |
| GSE53622 | SURF4 | 6836 | 15582 | 0.5034 | 0.0000 | |
| GSE53624 | SURF4 | 6836 | 19848 | 0.3280 | 0.0000 | |
| GSE63941 | SURF4 | 6836 | 222978_at | -0.3887 | 0.4146 | |
| GSE77861 | SURF4 | 6836 | 222978_at | 0.1101 | 0.5664 | |
| GSE97050 | SURF4 | 6836 | A_33_P3222783 | 0.5215 | 0.2483 | |
| SRP007169 | SURF4 | 6836 | RNAseq | -0.2062 | 0.4700 | |
| SRP008496 | SURF4 | 6836 | RNAseq | -0.0692 | 0.6237 | |
| SRP064894 | SURF4 | 6836 | RNAseq | 0.5879 | 0.0001 | |
| SRP133303 | SURF4 | 6836 | RNAseq | 0.6688 | 0.0030 | |
| SRP159526 | SURF4 | 6836 | RNAseq | 0.3872 | 0.0283 | |
| SRP193095 | SURF4 | 6836 | RNAseq | -0.0528 | 0.7510 | |
| SRP219564 | SURF4 | 6836 | RNAseq | 0.3710 | 0.2069 | |
| TCGA | SURF4 | 6836 | RNAseq | -0.0289 | 0.4722 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SURF4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SURF4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SURF4 | 6836 | 5 | 7 | 18 | |
| GSE20123 | SURF4 | 6836 | 5 | 7 | 18 | |
| GSE43470 | SURF4 | 6836 | 4 | 7 | 32 | |
| GSE46452 | SURF4 | 6836 | 6 | 13 | 40 | |
| GSE47630 | SURF4 | 6836 | 4 | 15 | 21 | |
| GSE54993 | SURF4 | 6836 | 3 | 3 | 64 | |
| GSE54994 | SURF4 | 6836 | 12 | 9 | 32 | |
| GSE60625 | SURF4 | 6836 | 0 | 0 | 11 | |
| GSE74703 | SURF4 | 6836 | 4 | 5 | 27 | |
| GSE74704 | SURF4 | 6836 | 3 | 5 | 12 | |
| TCGA | SURF4 | 6836 | 28 | 26 | 42 |
Total number of gains: 74; Total number of losses: 97; Total Number of normals: 317.
Somatic mutations of SURF4:
Generating mutation plots.
Highly correlated genes for SURF4:
Showing top 20/371 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SURF4 | DCTD | 0.747395 | 3 | 0 | 3 |
| SURF4 | DNAH1 | 0.737699 | 3 | 0 | 3 |
| SURF4 | RAB1A | 0.733287 | 3 | 0 | 3 |
| SURF4 | TNFRSF1B | 0.725645 | 3 | 0 | 3 |
| SURF4 | SMAP2 | 0.710424 | 3 | 0 | 3 |
| SURF4 | CD79B | 0.709539 | 3 | 0 | 3 |
| SURF4 | ALPK2 | 0.701035 | 3 | 0 | 3 |
| SURF4 | ZW10 | 0.700964 | 3 | 0 | 3 |
| SURF4 | ATP6V0D1 | 0.697417 | 4 | 0 | 4 |
| SURF4 | MRPL17 | 0.693429 | 4 | 0 | 4 |
| SURF4 | YIF1A | 0.685218 | 5 | 0 | 5 |
| SURF4 | MILR1 | 0.685127 | 3 | 0 | 3 |
| SURF4 | SEC11C | 0.685031 | 4 | 0 | 3 |
| SURF4 | CCT6A | 0.684543 | 3 | 0 | 3 |
| SURF4 | MAN1B1 | 0.684188 | 5 | 0 | 5 |
| SURF4 | PRRC1 | 0.681378 | 4 | 0 | 3 |
| SURF4 | PSMB7 | 0.676873 | 6 | 0 | 5 |
| SURF4 | XBP1 | 0.674171 | 4 | 0 | 3 |
| SURF4 | MMP14 | 0.672789 | 4 | 0 | 4 |
| SURF4 | CHST3 | 0.671842 | 3 | 0 | 3 |
For details and further investigation, click here
