| Full name: coiled-coil domain containing 65 | Alias Symbol: NYD-SP28|FLJ35732|FAP250|CFAP250|CILD27|DRC2 | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 85478 | HGNC ID: HGNC:29937 | Ensembl Gene: ENSG00000139537 | OMIM ID: 611088 |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC65:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC65 | 85478 | 1561523_at | -0.1253 | 0.4856 | |
| GSE26886 | CCDC65 | 85478 | 1561523_at | -0.0931 | 0.5133 | |
| GSE45670 | CCDC65 | 85478 | 1552321_a_at | -0.0816 | 0.3250 | |
| GSE53622 | CCDC65 | 85478 | 15038 | -0.0874 | 0.3233 | |
| GSE53624 | CCDC65 | 85478 | 15038 | -0.2461 | 0.0345 | |
| GSE63941 | CCDC65 | 85478 | 1561523_at | 0.2192 | 0.1019 | |
| GSE77861 | CCDC65 | 85478 | 1552321_a_at | 0.0092 | 0.9243 | |
| GSE97050 | CCDC65 | 85478 | A_23_P47904 | -0.0281 | 0.9180 | |
| SRP133303 | CCDC65 | 85478 | RNAseq | 0.8386 | 0.0061 | |
| TCGA | CCDC65 | 85478 | RNAseq | -0.8107 | 0.0080 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CCDC65 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC65:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC65 | 85478 | 6 | 1 | 23 | |
| GSE20123 | CCDC65 | 85478 | 6 | 1 | 23 | |
| GSE43470 | CCDC65 | 85478 | 4 | 1 | 38 | |
| GSE46452 | CCDC65 | 85478 | 8 | 1 | 50 | |
| GSE47630 | CCDC65 | 85478 | 11 | 2 | 27 | |
| GSE54993 | CCDC65 | 85478 | 0 | 5 | 65 | |
| GSE54994 | CCDC65 | 85478 | 4 | 1 | 48 | |
| GSE60625 | CCDC65 | 85478 | 0 | 0 | 11 | |
| GSE74703 | CCDC65 | 85478 | 4 | 1 | 31 | |
| GSE74704 | CCDC65 | 85478 | 4 | 1 | 15 | |
| TCGA | CCDC65 | 85478 | 16 | 12 | 68 |
Total number of gains: 63; Total number of losses: 26; Total Number of normals: 399.
Somatic mutations of CCDC65:
Generating mutation plots.
Highly correlated genes for CCDC65:
Showing top 20/77 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC65 | GOT1 | 0.761644 | 3 | 0 | 3 |
| CCDC65 | MPV17L | 0.741794 | 3 | 0 | 3 |
| CCDC65 | CD2BP2 | 0.729713 | 3 | 0 | 3 |
| CCDC65 | AKT1S1 | 0.726704 | 3 | 0 | 3 |
| CCDC65 | MPP7 | 0.724655 | 3 | 0 | 3 |
| CCDC65 | TRIM61 | 0.718556 | 3 | 0 | 3 |
| CCDC65 | TRIM65 | 0.718001 | 3 | 0 | 3 |
| CCDC65 | TNFSF14 | 0.705909 | 3 | 0 | 3 |
| CCDC65 | ZNF214 | 0.705141 | 3 | 0 | 3 |
| CCDC65 | GPKOW | 0.701138 | 3 | 0 | 3 |
| CCDC65 | E2F4 | 0.699647 | 4 | 0 | 4 |
| CCDC65 | ZNF90 | 0.698264 | 3 | 0 | 3 |
| CCDC65 | DNAH1 | 0.693883 | 4 | 0 | 3 |
| CCDC65 | KRT37 | 0.691195 | 3 | 0 | 3 |
| CCDC65 | C2orf16 | 0.686653 | 4 | 0 | 3 |
| CCDC65 | EEFSEC | 0.682893 | 3 | 0 | 3 |
| CCDC65 | PRAMEF10 | 0.677911 | 3 | 0 | 3 |
| CCDC65 | BIN2 | 0.673157 | 3 | 0 | 3 |
| CCDC65 | STOML2 | 0.67298 | 3 | 0 | 3 |
| CCDC65 | MAPK12 | 0.668934 | 4 | 0 | 3 |
For details and further investigation, click here
